Possible presence of O-linked carbohydrate in the human male reproductive tract CD52

2004 ◽  
Vol 62 (1-2) ◽  
pp. 91-100 ◽  
Author(s):  
A Hasegawa ◽  
H Sawai ◽  
H Tsubamoto ◽  
M Hori ◽  
S Isojima ◽  
...  
Keyword(s):  
Reproductive Tract ◽  
Male Reproductive Tract ◽  
Human Male

scholarly journals Location of a membrane-bound carbonic anhydrase isoenzyme (CA IV) in the human male reproductive tract.

1993 ◽  
Vol 41 (5) ◽  
pp. 751-757 ◽  
Author(s):  
S Parkkila ◽  
A K Parkkila ◽  
K Kaunisto ◽  
A Waheed ◽  
W S Sly ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Carbonic Anhydrase ◽  
Reproductive Tract ◽  
Muscle Layer ◽  
Apical Plasma Membrane ◽  
Specific Staining ◽  
Ductus Deferens ◽  
Male Reproductive Tract ◽  
Human Male ◽  
Membrane Bound

We studied the location of a membrane-bound carbonic anhydrase (CA IV) in the human male reproductive tract using a specific antiserum to human CA IV in conjunction with immunoblotting, immunoperoxidase, and immunofluorescence techniques. The microvilli and apical plasma membrane of the epithelial cells and the subepithelial smooth muscle layer of the epididymis, ductus deferens, and ampulla of the ductus deferens showed specific staining for CA IV. The epithelial cells of the prostate and seminal vesicle failed to stain for CA IV, however, whereas the subepithelial smooth muscle layer showed positive staining. No specific staining for CA II was seen in the epithelium of the epididymal duct or the proximal ductus deferens. The presence of CA IV in the epididymis was confirmed by immunoblotting, which revealed 35 KD and 33 KD polypeptides. The results show that the microvilli and the apical plasma membrane of the lining epithelium of the epididymal duct, ductus deferens, and ampulla of the ductus deferens contain the membrane-bound carbonic anhydrase isoenzyme IV. The presence of the enzyme in the epithelium of the epididymis and ductus deferens is probably linked to the acidification of the epididymal fluid that prevents premature sperm activation. Its physiological role in the smooth muscle cells remains to be elucidated.

scholarly journals Zika Virus Trafficking and Interactions in the Human Male Reproductive Tract

Pathogens ◽  
2018 ◽  
Vol 7 (2) ◽  
pp. 51 ◽  
Author(s):  
Lucia Da Silva
Keyword(s):  
Zika Virus ◽  
Reproductive Tract ◽  
Sexual Transmission ◽  
Host Cells ◽  
Future Research ◽  
Mosquito Vector ◽  
Male Reproductive Tract ◽  
Unprotected Sexual Intercourse ◽  
Human Male ◽  
Viral Interactions

Sexual transmission of Zika virus (ZIKV) is a matter of great concern. Infectious viral particles can be shed in semen for as long as six months after infection and can be transferred to male and female sexual partners during unprotected sexual intercourse. The virus can be found inside spermatozoa and could be directly transferred to the oocyte during fertilization. Sexual transmission of ZIKV can contribute to the rise in number of infected individuals in endemic areas as well as in countries where the mosquito vector does not thrive. There is also the possibility, as has been demonstrated in mouse models, that the vaginal deposition of ZIKV particles present in semen could lead to congenital syndrome. In this paper, we review the current literature to understand ZIKV trafficking from the bloodstream to the human male reproductive tract and viral interactions with host cells in interstitial spaces, tubule walls, annexed glands and semen. We hope to highlight gaps to be filled by future research and potential routes for vaccine and antiviral development.

scholarly journals Expression of epithelial cadherin in the human male reproductive tract and gametes and evidence of its participation in fertilization

2008 ◽  
Vol 14 (10) ◽  
pp. 561-571 ◽  
Author(s):  
C.I. Marin-Briggiler ◽  
M.F. Veiga ◽  
M.L. Matos ◽  
M.F. Gonzalez Echeverria ◽  
L.I. Furlong ◽  
...  
Keyword(s):  
Reproductive Tract ◽  
Male Reproductive Tract ◽  
Epithelial Cadherin ◽  
Human Male

Expression of dysadherin in the human male reproductive tract and in spermatozoa

2011 ◽  
Vol 96 (3) ◽  
pp. 554-561.e2 ◽  
Author(s):  
Nieves María Gabrielli ◽  
María Florencia Veiga ◽  
María Laura Matos ◽  
Silvina Quintana ◽  
Héctor Chemes ◽  
...  
Keyword(s):  
Reproductive Tract ◽  
Male Reproductive Tract ◽  
Human Male

X-Ray Diffraction Study on Human Male Reproductive Tract and Semen

2009 ◽  
Vol 76 (3) ◽  
pp. 198-202 ◽  
Author(s):  
K.P. Skandhan ◽  
S. Amith ◽  
K.P.S. Avni
Keyword(s):  
Seminal Vesicle ◽  
Calcium Silicate ◽  
Reproductive Tract ◽  
Prostate Gland ◽  
X Ray Diffraction ◽  
Male Reproductive Tract ◽  
X Ray ◽  
Human Male ◽  
Barium Silicate ◽  
Copper Gold

In the present study authors had separated testis, epididymis-caput, corpus, cauda, vas deferens, seminal vesicle, prostate gland and bulbourethral gland from human male reproductive tract, made it to ash form. Semen also underwent same procedure. All samples had undergone X-ray diffraction analysis. Results Results showed there where two distinct rings for each sample. We named it is “A” &” B”. Under “A” Barium silicate, Barium silicate hydrate and three metal complexes of copper, gold and zinc were seen. Under “B” Calcium silicate and calcium silicate hydrate were observed. Both “A” and “B” were seen throughout the length (expect for “A” is seminal vesicle) and in semen. Conclusions A tri metal complex of copper, gold and zinc is reported in this study, is first of its kind in Biology.

Zinc and magnesium in human male reproductive tract*

Andrologia ◽  
2009 ◽  
Vol 4 (3) ◽  
pp. 231-237 ◽  
Author(s):  
Chr. Lindholmer ◽  
H. Glauman
Keyword(s):  
Reproductive Tract ◽  
Male Reproductive Tract ◽  
Human Male

scholarly journals Phthalate Toxicity in Rats and Its Relation to Testicular Dysgenesis Syndrome in Humans

2021 ◽  
pp. 019262332110453
Author(s):  
Cynthia J. Willson
Keyword(s):  
Reproductive Tract ◽  
Normal Development ◽  
Environmental Chemicals ◽  
Testicular Development ◽  
Reproductive Disorders ◽  
Male Reproductive Tract ◽  
Testicular Dysgenesis Syndrome ◽  
Human Male ◽  
Testicular Dysgenesis ◽  
Common Etiology

This work describes the relevance of toxicology studies of environmental chemicals, with a focus on phthalates, for a hypothesis that certain human male reproductive disorders and diseases have a common etiology of disturbance of normal development in utero. The “Testicular Dysgenesis Syndrome” hypothesis in humans has parallels in male reproductive tract abnormalities and microscopic lesions reported for phthalate toxicity in rats. Additionally, this work describes the histological findings of abnormal testicular development (testicular dysgenesis) in rats as compared to those in humans, as well as potential findings in rats at different ages, from the embryo to the adult.

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