Hypotensive Resuscitation Combined with Polydatin Improve Microcirculation and Survival in a Rabbit Model of Uncontrolled Hemorrhagic Shock in Pregnancy

2011 ◽  
Vol 168 (1) ◽  
pp. 103-110 ◽  
Author(s):  
Chao Sheng ◽  
Yan-hong Yu ◽  
Ke-seng Zhao ◽  
Wei Qin ◽  
Chen-hong Wang
Keyword(s):  
Hemorrhagic Shock ◽  
Rabbit Model ◽  
Hypotensive Resuscitation ◽  
In Pregnancy

Increased survival with hypotensive resuscitation in a rabbit model of uncontrolled hemorrhagic shock in pregnancy

Resuscitation ◽  
2009 ◽  
Vol 80 (12) ◽  
pp. 1424-1430 ◽  
Author(s):  
Yan-hong Yu ◽  
Shi-peng Gong ◽  
Chao Sheng ◽  
Ke-seng Zhao ◽  
Robert F. Lodato ◽  
...  
Keyword(s):  
Hemorrhagic Shock ◽  
Rabbit Model ◽  
Hypotensive Resuscitation ◽  
In Pregnancy

scholarly journals Rabbit model of uncontrolled hemorrhagic shock and hypotensive resuscitation

2010 ◽  
Vol 43 (12) ◽  
pp. 1153-1159 ◽  
Author(s):  
J.B. Rezende-Neto ◽  
S.B. Rizoli ◽  
M.V. Andrade ◽  
T.A. Lisboa ◽  
J.R. Cunha-Melo
Keyword(s):  
Hemorrhagic Shock ◽  
Rabbit Model ◽  
Hypotensive Resuscitation

scholarly journals Effect of Hypotensive Resuscitation with a Novel Combination of Fluids in a Rabbit Model of Uncontrolled Hemorrhagic Shock

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e66916 ◽  
Author(s):  
Yu-ming Zhang ◽  
Bo Gao ◽  
Juan-juan Wang ◽  
Xu-de Sun ◽  
Xi-wen Liu
Keyword(s):  
Hemorrhagic Shock ◽  
Rabbit Model ◽  
Hypotensive Resuscitation

The influence of hemorrhagic shock on ocular microcirculation by obtained by laser speckle flowgraphy in a white rabbit model

2021 ◽  
Author(s):  
Kento Watanabe ◽  
Tomoaki Shiba ◽  
Tetsuya Komatsu ◽  
Kiyoshi Sakuma ◽  
Megumi Aimoto ◽  
...  
Keyword(s):  
Hemorrhagic Shock ◽  
Rabbit Model ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy

Effects of poloxamer 188 in a rabbit model of hemorrhagic shock

Resuscitation ◽  
1995 ◽  
Vol 29 (3) ◽  
pp. 265-266
Author(s):  
DC Mayer ◽  
SJ Strada ◽  
C Hoff ◽  
RL Hunter ◽  
M Artman
Keyword(s):  
Hemorrhagic Shock ◽  
Rabbit Model ◽  
Poloxamer 188

scholarly journals A Randomized Controlled Trial of Interleukin-1 Receptor Antagonist in a Rabbit Model of Ascending Infection in Pregnancy

2001 ◽  
Vol 9 (4) ◽  
pp. 233-237 ◽  
Author(s):  
Robert S. McDuffie ◽  
Jill K. Davies ◽  
Kimberly K. Leslie ◽  
Scott Lee ◽  
Michael P. Sherman ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Receptor Antagonist ◽  
Intravenous Infusion ◽  
Interleukin 1 ◽  
Rabbit Model ◽  
Prostaglandin E ◽  
Interleukin 1 Receptor Antagonist ◽  
Ascending Infection ◽  
Tnf Α ◽  
In Pregnancy

Objective:To determinewhether treatment with interleukin-1 receptor antagonist (IL1-ra) would affect amniotic fluid concentrations of tumor necrosis factor alpha (TNF-α) and prostaglandins or clinical or microbiological outcomes in a model of ascending bacterial infection in pregnancy.Methods:Timed pregnant New Zealand white rabbits at 70% of gestation underwent endoscopic inoculation of the cervices with106–107cfu Escherichia coli. Animals were randomly assigned in a blinded manner to a 5-h intravenous infusion of human IL1-ra (10 mg/kg) or placebo beginning 1 – 2 h after inoculation. Blood was drawn fromthe does for assay of serum IL1-ra concentration before inoculation, at mid-infusion, after the infusion ended and at necropsy. At necropsy, temperature and cultures were taken, and aspirated amniotic fluid was pooled for assays of TNF-α, prostaglandin E2( PGE2) and IL1-ra.Results:Serum IL1-ra concentrations rose to a mean of 2 mg/ml at mid-infusion and fell markedly after the infusion to concentrations barely detectable at necropsy. Between the two groups, there were no significant differences in the rates of fever or positive cultures or in amniotic fluid concentrations of PGE2or TNF-α.One unique finding was the demonstration that administration of human IL1-ra to the does resulted inmeasurable concentrationsof human IL1-ra in the amniotic fluid.Conclusions:Treatment with an intravenous infusion of human IL1-ra after cervical inoculation withE. colidid not affect clinical or microbiological outcomes or amniotic fluid concentrations of TNF-α or PGE2. This experiment provides the first demonstration of passageof human IL1-ra from the maternal bloodstreamto the amniotic fluid.

Hypotensive Resuscitation with Hypertonic Saline Dextran Improves Survival in a Rat Model of Hemorrhagic Shock at High Altitude

Shock ◽  
2017 ◽  
Vol 48 (2) ◽  
pp. 196-200 ◽  
Author(s):  
Jingxiang Zhao ◽  
Guoxing You ◽  
Bo Wang ◽  
Zhenwei Sun ◽  
Zhen Wang ◽  
...  
Keyword(s):  
Hemorrhagic Shock ◽  
High Altitude ◽  
Hypertonic Saline ◽  
Rat Model ◽  
Hypotensive Resuscitation
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