The search for a magic bullet to fight multiple organ failure secondary to ischemia/reperfusion injury and abdominal compartment syndrome

2013 ◽  
Vol 184 (2) ◽  
pp. 792-793 ◽  
Author(s):  
Weidun Alan Guo
Shock ◽  
2003 ◽  
Vol 20 (6) ◽  
pp. 483-492 ◽  
Author(s):  
Zsolt Balogh ◽  
Bruce A. McKinley ◽  
Charles S. Cox, ◽  
Steven J. Allen ◽  
Christine S. Cocanour ◽  
...  

2003 ◽  
Vol 54 (5) ◽  
pp. 848-861 ◽  
Author(s):  
Zsolt Balogh ◽  
Bruce A. McKinley ◽  
John B. Holcomb ◽  
Charles C. Miller ◽  
Christine S. Cocanour ◽  
...  

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
João Pedro Rocha ◽  
Bruno Miguel Sepodes ◽  
Maria Eduardo‐Figueira ◽  
Rosário Bronze ◽  
Beatriz Silva‐Lima ◽  
...  

2002 ◽  
Vol 53 (6) ◽  
pp. 1121-1128 ◽  
Author(s):  
Joao B. Rezende-Neto ◽  
Ernest E. Moore ◽  
Marcus Vinicius Melo de Andrade ◽  
Mauro Martins Teixeira ◽  
Felipe Assis Lisboa ◽  
...  

2020 ◽  
Vol 15 (2) ◽  
pp. 251-258
Author(s):  
Byeong hun Eom ◽  
Hyun Kyoung Lim ◽  
Nayoung Tae ◽  
Helen Ki Shinn

Background: Abdominal compartment syndrome (ACS) occurs due to increased abdominal cavity pressure, causes multiple organ damage, and leads to fatal consequences. Increased intraperitoneal pressure due to different reasons generally does not result in serious damage, due to the compliance of the abdominal wall. However, when the pressure exceeds the limit, ACS develops, thereby causing fatal damage to the organs. Case: A patient presented with rapid stomach swelling due to excessive food intake and was known to have bulimia nervosa, which had now resulted in ACS. Mental changes, abdominal distension, color change in the legs, acute kidney injury, and acidosis were seen. The patient expired due to ischemia-reperfusion injury and disseminated intravascular coagulation, which occurred after surgical decompression.Conclusions: Under suspected ACS conditions, we should be aware of various symptoms that can occur. Early attempts for decompression are helpful, and it is important to be prepared for reperfusion injury prior to surgical decompression attempts.


2021 ◽  
Author(s):  
Kuo-Ching Yuan ◽  
Chih-Yuan Fu ◽  
Hung-Chang Huang

Abdominal compartment syndrome (ACS) is a progressively increasing intraabdominal pressure of more than 20 mm Hg with new-onset thoracoabdominal organ dysfunction. Primary abdominal compartment syndrome means increased pressure due to injury or disease in the abdominopelvic region. Secondary abdominal compartment syndrome means disease originating from outside the abdomen, such as significant burns or sepsis. As the pressure inside the abdomen increases, organ failure occurs, and the kidneys and lungs are the most frequently affected. Managements of ACS are multidisciplinary. Conservative treatment with adequate volume supple and with aggressive hemodynamic support is the first step. Decompressive laparotomy with open abdomen is indicated when ACS is refractory to conservative treatment and complicated with multiple organ failure. ACS can result in a high mortality rate, and successful treatment requires cooperation between physicians, intensivists, and surgeons.


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