scholarly journals Rosmarinic acid reduces multiple organ failure in thermal injury and liver ischemia‐reperfusion injury

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
João Pedro Rocha ◽  
Bruno Miguel Sepodes ◽  
Maria Eduardo‐Figueira ◽  
Rosário Bronze ◽  
Beatriz Silva‐Lima ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Constantinos Nastos ◽  
Konstantinos Kalimeris ◽  
Nikolaos Papoutsidakis ◽  
Marios-Konstantinos Tasoulis ◽  
Panagis M. Lykoudis ◽  
...  

Liver ischemia/reperfusion injury has been extensively studied during the last decades and has been implicated in the pathophysiology of many clinical entities following hepatic surgery and transplantation. Apart from its pivotal role in the pathogenesis of the organ’s post reperfusion injury, it has also been proposed as an underlying mechanism responsible for the dysfunction and injury of other organs as well. It seems that liver ischemia and reperfusion represent an event with “global” consequences that influence the function of many remote organs including the lung, kidney, intestine, pancreas, adrenals, and myocardium among others. The molecular and clinical manifestation of these remote organs injury may lead to the multiple organ dysfunction syndrome, frequently encountered in these patients. Remote organ injury seems to be in part the result of the oxidative burst and the inflammatory response following reperfusion. The present paper aims to review the existing literature regarding the proposed mechanisms of remote organ injury after liver ischemia and reperfusion.


2015 ◽  
Vol 36 (12) ◽  
pp. 1300
Author(s):  
Lin-lin CAI ◽  
Hai-long FU ◽  
Qing-qing ZHANG ◽  
Yong-hua LI ◽  
Qiu-feng ZHU ◽  
...  

2019 ◽  
Author(s):  
Xiaoliang Xu ◽  
Zechuan Zhang ◽  
Yijun Lu ◽  
Qikai Sun ◽  
Yang Liu ◽  
...  

2021 ◽  
Author(s):  
Camila Dossi ◽  
Romina Vargas ◽  
Rodrigo Valenzuela ◽  
Luis Videla

Liver ischemia-reperfusion injury (IRI) is a phenomenon inherent to hepatic surgery that severely compromises the organ functionality, whose underlying mechanisms involve cellular and molecular interrelated processes leading to the development...


Hepatology ◽  
2020 ◽  
Vol 72 (4) ◽  
pp. 1394-1411 ◽  
Author(s):  
Zhongjie Yi ◽  
Meihong Deng ◽  
Melanie J. Scott ◽  
Guang Fu ◽  
Patricia A. Loughran ◽  
...  

2018 ◽  
Vol 102 ◽  
pp. S708
Author(s):  
Ivan Linares ◽  
Agata Bartczak ◽  
Kaveh Farrokhi ◽  
Dagmar Kollmann ◽  
Moritz Kaths ◽  
...  

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