scholarly journals In vitro studies of the anticancer action of Tectaria cicutaria in human cancer cell lines: G0/G1 p53-associated cell cycle arrest-Part I

2018 ◽  
Vol 8 (4) ◽  
pp. 459-464 ◽  
Author(s):  
Preeti Gajendra Karade ◽  
Namdeo Ramhari Jadhav
2003 ◽  
Vol 106 (1) ◽  
pp. 125-137 ◽  
Author(s):  
Wen-Sen Lee ◽  
Rong-Jane Chen ◽  
Ying-Jan Wang ◽  
How Tseng ◽  
Jiiang-Huei Jeng ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (94) ◽  
pp. 91386-91393 ◽  
Author(s):  
Jianfa Zong ◽  
Dongxu Wang ◽  
Weiting Jiao ◽  
Liang Zhang ◽  
Guanhu Bao ◽  
...  

Oleiferasaponin C6 was isolated from Camellia oleifera Abel. and inhibits proliferation through inducing cell-cycle arrest and apoptosis on cancer cell lines in vitro.


2011 ◽  
Vol 226 (8) ◽  
pp. 1989-1997 ◽  
Author(s):  
Christopher Bartlett ◽  
Tess J. Orvis ◽  
Gary S. Rosson ◽  
Bernard E. Weissman

Author(s):  
Lamiae Belayachi ◽  
Clara Aceves-Luquero ◽  
nawel Merghoub ◽  
Silvia Fernandez de Mattos ◽  
Saaid Amzazi ◽  
...  

2010 ◽  
Vol 54 (11) ◽  
pp. 1574-1584 ◽  
Author(s):  
Qi-Qi Mao ◽  
Yu Bai ◽  
Yi-Wei Lin ◽  
Xiang-Yi Zheng ◽  
Jie Qin ◽  
...  

2022 ◽  
Vol 20 (2) ◽  
pp. 345-350
Author(s):  
Wesam M. Salama ◽  
Sabry A. El-Naggar

Purpose: In this study, the cytotoxicity of scorpion Leurius quinquestratus crude venom (LQCV) was evaluated in vitro in selected human cancer cell lines. Methods: Breast (MCF-7), hepatocellular (HepG-2), colon (CaCo-2), cervix (HeLa) and alveolar (A-549) adenocarcinoma cell lines were tested. MTT assay and median inhibition concentration (IC50), apoptotic assay, caspase 3, P53, Bcl-2 proteins and cell cycle were determined. Results: 24 hrs post-treatment, CaCo-2 represented the most sensitive cell line (IC50 of 4.12 μg/mL). Due to the exposure to 1/10 IC50 of LQCV, the percentage of the apoptotic cells, caspase 3, and P53 proteins were increased significantly (P<0.05) while Bcl-2 was decreased in comparison to untreated cells. Treatment with LQCV induced cell cycle arrest at G1 and G2/M phases. Conclusion: LQCV displays potent cytotoxicity against selected human cell lines in vitro. Thus, the material could become a potent agent for the management of some cancers.


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