MP15-08 AN EX-VIVO ANALYSIS OF VARIOUS SUTURE MATERIALS AND TECHNIQUES, AND TYPES OF URINARY CATHETERS IN VESICOURETHRAL ANASTOMOTIC TENSILE STRENGTH AND CATHETER DISLODGMENT: A PORCINE MODEL

Background: Barbed suture use has become more popular as technology and materials have advanced. Minimal data exist regarding performance of the 2 commercially available products, V-LocTM and StratafixTM in tendon repairs. The purpose of this study was to compare gap resistance and ultimate tensile strength of both suture materials and nonbarbed suture in a porcine ex vivo model. Methods: Porcine flexor tendons were harvested and divided into 3 groups of 10 of varying suture material (3-0 PDS™, 3-0 V- V-Loc 180™, or 3-0 Stratafix™). A modified 4-strand cruciate technique was used to repair each tendon. Knotless repair was performed using barbed suture, whereas a buried 6-throw square knot was done using conventional suture. A servohydrolic tester was used for biomechanical testing of linear 2-mm gap resistance and maximum tensile strength. Results: No difference was found in 2-mm gap resistance among the 3 groups. No difference was found in ultimate tensile strength between V-Loc™ (76.0 ± 9.4 N) and Stratafix™ (68.1 ± 8.4 N) repairs, but the ultimate strength of the PDS™ control group (83.4 ± 10.0 N) was significantly higher than that of Stratafix™. Conclusions: Barbed (knotless) and nonbarbed suture repairs demonstrate equivalent 2-mm gap resistance. Stratafix™ repairs show slightly inferior performance to nonbarbed repairs in ultimate tensile strength, although this occurred at gap distances far beyond the 2-mm threshold for normal tendon gliding. Both barbed and nonbarbed 4-strand cruciate flexor tendon repairs may require peripheral repair to withstand physiologic loads.

Download Full-text

Biomechanical Properties and Biocompatibility of a Non-Absorbable Elastic Thread

Journal of Functional Biomaterials ◽

10.3390/jfb10040051 ◽

2019 ◽

Vol 10 (4) ◽

pp. 51 ◽

Cited By ~ 2

Author(s):

Yeji Choi ◽

Moonseok Kang ◽

Moon Seop Choi ◽

Jennifer Kim Song ◽

Eugene Lih ◽

...

Keyword(s):

Tensile Strength ◽

Potential Role ◽

Ex Vivo ◽

Biomechanical Properties ◽

In Vitro Cytotoxicity ◽

Current Experiment ◽

Suture Materials ◽

Frictional Properties ◽

Elastic Thread

To date, extensive studies have been conducted to assess diverse types of sutures. But there is a paucity of data regarding biomechanical properties of commonly used suture materials. In the current experiment, we compared biomechanical properties and biocompatibility, such as tensile strength and elongation, the degree of bovine serum albumin (BSA) release, in vitro cytotoxicity and ex vivo frictional properties, between a non-absorbable elastic thread (NAT; HansBiomed Co. Ltd., Seoul, Korea) (NAT-R: NAT with a rough surface, NAT-S: NAT with a smooth surface) and the Elasticum® (Korpo SRL, Genova, Italy). The degree of tensile strength and elongation of Si threads was significantly higher in both the NAT-R and -S as compared with the Elasticum® (p < 0.05). Moreover, the degree of tensile strength and elongation of PET threads was significantly lower in both NAT-R and -S as compared with the Elasticum® (p < 0.05). Furthermore, the degree of tensile strength and elongation of braided Si/PET threads was significantly lower in NAT-S as compared with NAT-R and Elasticum® (p < 0.05). The degree of BSA release was significantly higher in the NAT-R as compared with Elasticum® and NAT-S throughout a 2-h period in the descending order (p < 0.05). The degree of cell viability was significantly higher in both NAT-R and -S as compared with Elasticum® (p < 0.05). The degree of coefficient of friction as well as the frictional force and strength was significantly higher in NAT-R as compared with NAT-S and Elasticum® (p < 0.05). NAT had a higher degree of biomechanical properties and biocompatibility as compared with Elasticum®. But further experimental and clinical studies are warranted to compare the efficacy, safety, and potential role as a carrier for drug delivery between NAT and Elasticum®.

Download Full-text

Differential Outcomes for Long Term ex vivo Lung Perfusion in a Porcine Model - With or without Red Cells?

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0035-1544536 ◽

2015 ◽

Vol 63 (S 01) ◽

Author(s):

W. Sommer ◽

M. Avsar ◽

J. Salman ◽

C. Kühn ◽

I. Tudorache ◽

...

Keyword(s):

Porcine Model ◽

Ex Vivo ◽

Lung Perfusion ◽

Red Cells ◽

Ex Vivo Lung Perfusion ◽

Differential Outcomes

Download Full-text

Robotic-assisted cholecystectomy is superior to laparoscopic cholecystectomy in the initial training for surgical novices in an ex vivo porcine model: a randomized crossover study

Surgical Endoscopy ◽

10.1007/s00464-021-08373-6 ◽

2021 ◽

Author(s):

E. Willuth ◽

S. F. Hardon ◽

F. Lang ◽

C. M. Haney ◽

E. A. Felinska ◽

...

Keyword(s):

Laparoscopic Cholecystectomy ◽

Crossover Study ◽

Porcine Model ◽

Haptic Feedback ◽

Ex Vivo ◽

Operating Time ◽

Surgical Performance ◽

Robotic Assisted ◽

Subjective Workload ◽

Randomized Crossover Study

Abstract Background Robotic-assisted surgery (RAS) potentially reduces workload and shortens the surgical learning curve compared to conventional laparoscopy (CL). The present study aimed to compare robotic-assisted cholecystectomy (RAC) to laparoscopic cholecystectomy (LC) in the initial learning phase for novices. Methods In a randomized crossover study, medical students (n = 40) in their clinical years performed both LC and RAC on a cadaveric porcine model. After standardized instructions and basic skill training, group 1 started with RAC and then performed LC, while group 2 started with LC and then performed RAC. The primary endpoint was surgical performance measured with Objective Structured Assessment of Technical Skills (OSATS) score, secondary endpoints included operating time, complications (liver damage, gallbladder perforations, vessel damage), force applied to tissue, and subjective workload assessment. Results Surgical performance was better for RAC than for LC for total OSATS (RAC = 77.4 ± 7.9 vs. LC = 73.8 ± 9.4; p = 0.025, global OSATS (RAC = 27.2 ± 1.0 vs. LC = 26.5 ± 1.6; p = 0.012, and task specific OSATS score (RAC = 50.5 ± 7.5 vs. LC = 47.1 ± 8.5; p = 0.037). There were less complications with RAC than with LC (10 (25.6%) vs. 26 (65.0%), p = 0.006) but no difference in operating times (RAC = 77.0 ± 15.3 vs. LC = 75.5 ± 15.3 min; p = 0.517). Force applied to tissue was similar. Students found RAC less physical demanding and less frustrating than LC. Conclusions Novices performed their first cholecystectomies with better performance and less complications with RAS than with CL, while operating time showed no differences. Students perceived less subjective workload for RAS than for CL. Unlike our expectations, the lack of haptic feedback on the robotic system did not lead to higher force application during RAC than LC and did not increase tissue damage. These results show potential advantages for RAS over CL for surgical novices while performing their first RAC and LC using an ex vivo cadaveric porcine model. Registration number researchregistry6029 Graphic abstract

Download Full-text

Development of a gel dedicated to gel immersion endoscopy

Endoscopy International Open ◽

10.1055/a-1396-4236 ◽

2021 ◽

Vol 09 (06) ◽

pp. E918-E924

Author(s):

Tomonori Yano ◽

Atsushi Ohata ◽

Yuji Hiraki ◽

Makoto Tanaka ◽

Satoshi Shinozaki ◽

...

Keyword(s):

Electrical Conductivity ◽

Porcine Model ◽

Ex Vivo ◽

In Vitro Experiments ◽

Efficacy And Safety ◽

Coagulative Necrosis ◽

Novel Technique ◽

In Vivo Experiments

Abstract Backgrounds and study aims Gel immersion endoscopy is a novel technique to secure the visual field during endoscopy. The aim of this study was to develop a dedicated gel for this technique. Methods To identify appropriate viscoelasticity and electrical conductivity, various gels were examined. Based on these results, the dedicated gel “OPF-203” was developed. Efficacy and safety of OPF-203 were evaluated in a porcine model. Results In vitro experiments showed that a viscosity of 230 to 1900 mPa·s, loss tangent (tanδ) ≤ 0.6, and hardness of 240 to 540 N/cm2 were suitable. Ex vivo experiments showed electrical conductivity ≤ 220 μS/cm is appropriate. In vivo experiments using gastrointestinal bleeding showed that OPF-203 provided clear visualization compared to water. After electrocoagulation of gastric mucosa in OPF-203, severe coagulative necrosis was not observed in the muscularis but limited to the mucosa. Conclusions OPF-203 is useful for gel immersion endoscopy.

Download Full-text

Lowering Perfusate Temperature From 37°C to 32°C Diminishes Function in a Porcine Model of Ex Vivo Kidney Perfusion

Transplantation Direct ◽

10.1097/txd.0000000000000655 ◽

2017 ◽

Vol 3 (3) ◽

pp. e140 ◽

Cited By ~ 13

Author(s):

Thomas D. Adams ◽

Meeta Patel ◽

Sarah A. Hosgood ◽

Michael L. Nicholson

Keyword(s):

Porcine Model ◽

Ex Vivo ◽

Kidney Perfusion

Download Full-text

Description of a new, endoscopic technique to remove the over-the-scope-clip in an ex vivo porcine model (with video)

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2012.07.036 ◽

2012 ◽

Vol 76 (5) ◽

pp. 1009-1013 ◽

Cited By ~ 19

Author(s):

Helmut Neumann ◽

Hiwot Diebel ◽

Klaus Mönkemüller ◽

Andreas Nägel ◽

Dane Wildner ◽

...

Keyword(s):

Porcine Model ◽

Ex Vivo ◽

Endoscopic Technique ◽

Over The Scope Clip

Download Full-text

The Effect of Suture Materials on the Biomechanical Performance of Different Flexor Tendon Repairs and the Concept of Construct Efficiency

The Journal of Hand Surgery (Asian-Pacific Volume) ◽

10.1142/s2424835518500285 ◽

2018 ◽

Vol 23 (02) ◽

pp. 243-247

Author(s):

Yoke Rung Wong ◽

Austin Mun Kitt Loke ◽

Shian Chao Tay

Keyword(s):

Tensile Strength ◽

Ultimate Tensile Strength ◽

Tensile Testing ◽

Flexor Tendon ◽

Experimental Results ◽

Suture Materials ◽

Nylon Suture ◽

Biomechanical Strength ◽

Repair Techniques

Background: To propose a new term (‘construct efficiency’) for the evaluation of multi strands flexor tendon repairs using different suture materials. Methods: A total of twenty specimens from 4-0 braided polyblend sutures (FiberLoop/FiberWire; Arthrex, Naples, FL) and 4-0 nylon sutures (Supramid Extra II; S. Jackson, Inc., Alexandria, VA) were subjected to tensile testing using Pneumatic Cord-and-Yarn Grips (Instron Corp., Canton MA, USA). The ultimate tensile strengths of the suture materials were measured. The expected repair strengths and construct efficiencies were computed based on the experimental results and from available literature on actual repair strengths of the 4-strand Becker, Cruciate repairs and 6-strand Tang, modified Lim-Tsai repairs. Results: The ultimate tensile strength of nylon suture was 15.4 ± 0.6N, lower than that of braided polyblend suture (45.3 ± 2.3N) with a difference of 194%. The construct efficiency of multi strand repairs varied with respect to different repair techniques and suture materials. It was found that the Becker repairs using FiberWire had the highest construct efficiency (55.7%) followed by the modified Lim-Tsai using Supramid (50.9%), Tang repair using Supramid (49.8%), Cruciate repair using Fiberwire (49.1%), and modified Lim-Tsai repair using FiberLoop (33.5%). Conclusions: The construct efficiency is more accurate in showing that, in terms of biomechanical strength, the use of FiberWire for the 4-strand Becker and Cruciate repair is more efficient than that of using FiberLoop for 6-strand modified Lim-Tsai repair.

Download Full-text