scholarly journals Are Generic Health State Utility Instruments Sufficiently Sensitive To Capture Changes In Health-Related Quality of Life In Patients With Visual Disorders?

2017 ◽  
Vol 20 (9) ◽  
pp. A805
Author(s):  
AM Buchanan-Hughes ◽  
JS Evans ◽  
RC Beale ◽  
C Tournier ◽  
L Pope
Keyword(s):  
Quality Of Life ◽  
Health State Utility ◽  
Health State ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Visual Disorders

scholarly journals Economic Burden And Health-Related Quality Of Life Of Patients With Cystic Fibrosis In Bulgaria

Folia Medica ◽  
2015 ◽  
Vol 57 (1) ◽  
pp. 56-64 ◽  
Author(s):  
Georgi G. Iskrov ◽  
Rumen S. Stefanov ◽  
Julio López-Bastida ◽  
Renata Linertová ◽  
Juan Oliva-Moreno ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Economic Burden ◽  
Resource Utilisation ◽  
Informal Carer ◽  
Health State ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

AbstractObjective:The aim of this study was to determine the economic burden from a societal perspective and health-related quality of life (HRQOL) of patients with cystic fibrosis (CF) in Bulgaria.Materials and methods:We conducted a cross-sectional study of 33 patients with CF and 17 caregivers from Bulgaria. Data on socio-demographic characteristics, health resource utilisation, informal care, labor productivity losses and HRQOL were collected from questionnaires completed by patients or their caregivers. HRQOL was evaluated with the EuroQol 5-domain (EQ-5D-3L) questionnaire.Results:Median annual costs of CF in Bulgaria were € 24 152 per patient in 2012 as a reference year. Median annual costs for children were found to be significantly higher than those for adults – € 31 945 vs. € 15 714 (p = 0.012). This outcome came from statistically significant differences in costs for main informal carer (p < 0.001) and costs for other informal carers (p = 0.022). As a single cost item, drugs had the biggest monetary impact. Median annual drug costs were € 13 059. Bulgarian CF patients showed low HRQOL results – 50 median VAS score and 0.592 median health utilities. A quarter of patients even rated their health state as worse than death.Conclusion:CF patients from Eastern Europe remain a vulnerable population with risk factors for worse health outcomes. Our study provided a state-of-the art analysis that facilitates the elaboration, adoption and application of targeted public health policies to tackle CF-related problems at national and European level.

Does it really matter where you live? A panel data multilevel analysis of Swedish municipality-level social capital on individual health-related quality of life

2006 ◽  
Vol 1 (3) ◽  
pp. 209-235 ◽  
Author(s):  
M. Kamrul Islam ◽  
Juan Merlo ◽  
Ichiro Kawachi ◽  
Martin Lindström ◽  
Kristina Burström ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Capital ◽  
Health Status ◽  
Panel Data ◽  
Health State ◽  
Health Related Quality ◽  
Individual Health ◽  
Related Quality ◽  
Health Related

We test whether individual health status is related to area-level social capital measured by rates of voting participation in municipal political elections, controlling for personal characteristics, where health status is measured by mapping responses to interview survey questions into the generic health-related quality of life measure (HRQoL) the EQ-5D in order to derive the health state scores. The analysis is based on unbalanced panel data from Statistic Sweden's Survey of Living Conditions (the ULF survey) and a 3-level multilevel regression analysis, where level 1 consists of a total of 31,585 observations for 24,419 individuals at level 2 nested within 275 Swedish municipalities at level 3. We find that the health state scores increase significantly with municipality election rates. This result is robust to a number of measurement and specification issues explored in a sensitivity analysis. However, almost all variation in health status exists across individuals (more than 98%), which demonstrates that even if social capital (and other contextual variables) may be significant it is of less importance, at least at the municipality level in Sweden.

Development and Validation of a New Instrument to Measure Health-related Quality of Life in Patients with Psoriatic Arthritis: The VITACORA-19

2014 ◽  
Vol 41 (10) ◽  
pp. 2008-2017 ◽  
Author(s):  
Juan Carlos Torre-Alonso ◽  
Jordi Gratacós ◽  
José Santos Rey-Rey ◽  
Juan Pablo Valdazo de Diego ◽  
Ana Urriticoechea-Arana ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis ◽  
Health State ◽  
Sensitivity To Change ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Group A ◽  
Group B

Objective.To develop/validate an instrument to measure health-related quality of life (HRQoL) in patients with psoriatic arthritis (PsA), for use in clinical studies.Methods.An item pool of 35 items was generated following standardized procedures. Item reduction was performed using clinimetric and psychometric approaches after administration to 66 patients with PsA. The resulting instrument, the VITACORA-19, consists of 19 items. Its validity content, internal consistency, test-retest reliability, known groups/convergent validity, and sensitivity to change were tested in a longitudinal and multicenter study conducted in 10 hospitals in Spain, with 323 patients who also completed the EuroQol 5-dimensional questionnaire (EQ-5D) and a health status transition item. There were 3 study groups: group A (n = 209, patients with PsA), group B (n = 71, patients with arthritis without psoriatic aspect, patients with arthrosis, and patients with dermatitis), and group C (n = 43, healthy controls).Results.The questionnaire was considered easy/very easy to answer by 94.7% of the patients with PsA. The factorial analysis clearly identified only 1 factor. Cronbach’s alpha coefficient and interclass correlation coefficients exceeded 0.90. Statistically significant differences (p < 0.001) were observed between groups: subjects from group C had better HRQoL, followed by group B, and finally group A had the worst HRQoL. The VITACORA-19 scores showed significant correlations (p < 0.001) to PsA disease activity, EQ-5D, and perceived health state, scoring the patients with better health state higher. The minimum important difference was established as an 8-point change in the global score.Conclusion.The Spanish-developed VITACORA-19, designed to measure HRQoL in patients with PsA, has good validity, reliability, and sensitivity to change.

scholarly journals Population norms of health-related quality of life in Moscow, Russia: the EQ-5D-5L-based survey

2020 ◽  
Author(s):  
Malwina Hołownia-Voloskova ◽  
Aleksei Tarbastaev ◽  
Dominik Golicki
Keyword(s):  
Quality Of Life ◽  
Positive Impact ◽  
Health State ◽  
Health Related Quality ◽  
Population Norms ◽  
Russian Paper ◽  
Related Quality ◽  
Health Related ◽  
Eq Vas

Abstract Purpose To develop population norms for the EQ-5D-5L questionnaire based on a representative sample of Moscow citizens. Methods We used quota sampling accounting for sex, age group and administrative district of residence. Respondents in randomly selected outdoor and indoor locations were surveyed with the official Russian paper-and-pencil version of the EQ-5D-5L questionnaire and a set of socio-demographic questions. We estimated four types of EQ-5D results: the distribution of limitations according to EQ-5D-5L dimensions, the perception of the health-related quality of life (HRQoL) with a visual analogue scale (EQ VAS), the unweighted score for a respondent’s health state (Level Sum Score, LSS) and the Russian health preferences-based weighted score (EQ index). In order to estimate the EQ-5D-5L index, we used a newly developed Russian EQ-5D-3L value set, together with EuroQol Group cross-over methodology. Results A total of 1020 respondents (18–93 years old) from the general Moscow adult population completed the EQ-5D-5L questionnaire. HRQoL domains with the largest number of identified health limitations were pain/discomfort (48.6%) and anxiety/depression (44.1%). Two hundred seventy-nine respondents (27.0%) did not report any health restrictions. The mean EQ VAS and EQ-5D-5L index were 74.1 (SD 17.3) and 0.907 (0.106) respectively. Multivariate analysis showed that female sex, advanced age and lack of access to the Internet had a negative influence on HRQoL, whereas residence in certain districts had a positive impact. Conclusions The study provides population norms of health-related quality of life in Moscow, measured according to the EQ-5D-5L questionnaire. These reference values can be used to optimise the effectiveness of resource allocation in healthcare.

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