The reported increase in the prevalence of diabetes mellitus is expected to be accompanied by a corresponding increase in associated complications. Foot problems are important public health complications of diabetes mellitus. A major obstacle in the management of foot ulcers in diabetes is the colonisation of wounds by virulent pathogens, increasing morbidity and mortality. This was a review of the profile, bacteriology and antibiotic susceptibility pattern of foot ulcers in type 2 diabetes mellitus to aid planning of services and provides a sensible approach to empirical antibiotic therapy while awaiting culture and sensitivity report. It was a hospital based retrospective study in individuals with type 2 diabetes mellitus admitted for foot ulcer(s) over a 3 year period (2012 - 2014) at the Federal Medical Centre. Approval for the study was obtained from the Ethics Committee of the institution. Relevant data (gender, age, residence, occupation, diabetes mellitus duration, ulcer duration, glycoslated haemoglobin status) were extracted from the files. One hundred and nine type 2 diabetes mellitus case files made up of 44 females and 65 males (1:1.5) with a mean age of 53.5±11.4 years were extracted. They were mostly farmers in their fifties with poor glycaemic control who had type 2 diabetes mellitus for more than a decade and foot ulcers for more than 6 months. Late presentation, poor glycaemic control, high rate of wound infection with Staphylococcus aureus, resistance to Penicillins and sensitivity to Quinolones were noted.