Abstract
Background
Influenza health resource utilization studies are important to inform future public health policies and prevent outbreaks. This study aimed to describe influenza prevalence, vaccination, and treatment among outpatients in the United States and to evaluate population-level characteristics associated with influenza health resource utilization.
Methods
Data were extracted from the National Ambulatory and National Hospital Ambulatory Medical Care Surveys (2009 to 2016). Prevalence rates were described as influenza visits (defined by ICD-9-CM or ICD-10 code) per 1,000 total visits overall and by flu year, month, region, race, and age group. Influenza vaccination and antiviral treatments were identified by Multum code(s) and presented as vaccination visits per 1,000 total visits and the percentage of patients diagnosed with influenza receiving antiviral treatment.
Results
Over 19.2 million visits included an influenza diagnosis, with rates ranging from 1.2 per 1,000 during 2014-2015 to 3.7 per 1,000 during 2009-2010. Rates were highest in the South (3.6 per 1,000), in December (5.2), among Black patients (2.8), and those less than 18 years (6.8). Vaccination rates were highest during 2014-2015 (29.3 per 1,000) and lowest during 2011-2012 (15.5 per 1,000), in the West (23.4), in October (69.2), among “other race” patients (26.2), and age less than 18 years (51.4). Overall, 39.4% of patients with an influenza diagnosis received an antiviral.
Conclusions
Overall, there were no major changes in influenza diagnosis or vaccination rates. Patient populations with lower vaccination rates had higher influenza diagnosis rates. Future campaigns should promote influenza vaccinations particularly in underserved populations.
Real-World Evidence of Reductions in Health Resource Utilization (HRU) and Improved Efficacy Outcomes Associated with Reslizumab Treatment in Adults with Severe Eosinophilic Asthma (SEA) in the United States