Inferring human microbe-drug associations via multiple kernel fusion on graph neural network

2021 ◽  
pp. 107888
Author(s):  
Hongpeng Yang ◽  
Yijie Ding ◽  
Jijun Tang ◽  
Fei Guo
Author(s):  
Huan Song ◽  
Jayaraman J. Thiagarajan ◽  
Prasanna Sattigeri ◽  
Karthikeyan Natesan Ramamurthy ◽  
Andreas Spanias

2014 ◽  
Vol 30 (17) ◽  
pp. i364-i370 ◽  
Author(s):  
J. Brayet ◽  
F. Zehraoui ◽  
L. Jeanson-Leh ◽  
D. Israeli ◽  
F. Tahi

2018 ◽  
Vol 2018 ◽  
pp. 1-15 ◽  
Author(s):  
Hong Zheng ◽  
Haibin Li ◽  
Xingjian Lu ◽  
Tong Ruan

Air quality prediction is an important research issue due to the increasing impact of air pollution on the urban environment. However, existing methods often fail to forecast high-polluting air conditions, which is precisely what should be highlighted. In this paper, a novel multiple kernel learning (MKL) model that embodies the characteristics of ensemble learning, kernel learning, and representative learning is proposed to forecast the near future air quality (AQ). The centered alignment approach is used for learning kernels, and a boosting approach is used to determine the proper number of kernels. To demonstrate the performance of the proposed MKL model, its performance is compared to that of classical autoregressive integrated moving average (ARIMA) model; widely used parametric models like random forest (RF) and support vector machine (SVM); popular neural network models like multiple layer perceptron (MLP); and long short-term memory neural network. Datasets acquired from a coastal city Hong Kong and an inland city Beijing are used to train and validate all the models. Experiments show that the MKL model outperforms the other models. Moreover, the MKL model has better forecast ability for high health risk category AQ.


Author(s):  
Rong Wang ◽  
Jitao Lu ◽  
Yihang Lu ◽  
Feiping Nie ◽  
Xuelong Li

The multiple kernel k-means (MKKM) and its variants utilize complementary information from different kernels, achieving better performance than kernel k-means (KKM). However, the optimization procedures of previous works all comprise two stages, learning the continuous relaxed label matrix and obtaining the discrete one by extra discretization procedures. Such a two-stage strategy gives rise to a mismatched problem and severe information loss. To address this problem, we elaborate a novel Discrete Multiple Kernel k-means (DMKKM) model solved by an optimization algorithm that directly obtains the cluster indicator matrix without subsequent discretization procedures. Moreover, DMKKM can strictly measure the correlations among kernels, which is capable of enhancing kernel fusion by reducing redundancy and improving diversity. What’s more, DMKKM is parameter-free avoiding intractable hyperparameter tuning, which makes it feasible in practical applications. Extensive experiments illustrated the effectiveness and superiority of the proposed model.


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