Kinesiophobia and maladaptive coping strategies prevent improvements in pain catastrophizing following pain neuroscience education in fibromyalgia/chronic fatigue syndrome: Pooled results from 2 randomized controlled trials

2016 ◽  
Vol 25 ◽  
pp. e135-e136 ◽  
Author(s):  
A. Malfliet ◽  
J. Van Oosterwijck ◽  
M. Meeus ◽  
B. Cagnie ◽  
L. Danneels ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Randomized Controlled Trials ◽  
Coping Strategies ◽  
Pain Catastrophizing ◽  
Chronic Fatigue ◽  
Controlled Trials ◽  
Maladaptive Coping ◽  
Randomized Controlled ◽  
Fatigue Syndrome ◽  
Neuroscience Education

scholarly journals Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Do-Young Kim ◽  
Jin-Seok Lee ◽  
Samuel-Young Park ◽  
Soo-Jin Kim ◽  
Chang-Gue Son
Keyword(s):  
Systematic Review ◽  
Chronic Fatigue Syndrome ◽  
Randomized Controlled Trials ◽  
Chronic Fatigue ◽  
Myalgic Encephalomyelitis ◽  
Controlled Trials ◽  
Pharmacological Interventions ◽  
Case Definitions ◽  
Randomized Controlled ◽  
Fatigue Syndrome

Abstract Background Although medical requirements are urgent, no effective intervention has been proven for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). To facilitate the development of new therapeutics, we systematically reviewed the randomized controlled trials (RCTs) for CFS/ME to date. Methods RCTs targeting CFS/ME were surveyed using two electronic databases, PubMed and the Cochrane library, through April 2019. We included only RCTs that targeted fatigue-related symptoms, and we analyzed the data in terms of the characteristics of the participants, case definitions, primary measurements, and interventions with overall outcomes. Results Among 513 potentially relevant articles, 56 RCTs met our inclusion criteria; these included 25 RCTs of 22 different pharmacological interventions, 29 RCTs of 19 non-pharmacological interventions and 2 RCTs of combined interventions. These studies accounted for a total of 6956 participants (1713 males and 5243 females, 6499 adults and 457 adolescents). CDC 1994 (Fukuda) criteria were mostly used for case definitions (42 RCTs, 75.0%), and the primary measurement tools included the Checklist Individual Strength (CIS, 35.7%) and the 36-item Short Form health survey (SF-36, 32.1%). Eight interventions showed statistical significance: 3 pharmacological (Staphypan Berna, Poly(I):poly(C12U) and CoQ10 + NADH) and 5 non-pharmacological therapies (cognitive-behavior-therapy-related treatments, graded-exercise-related therapies, rehabilitation, acupuncture and abdominal tuina). However, there was no definitely effective intervention with coherence and reproducibility. Conclusions This systematic review integrates the comprehensive features of previous RCTs for CFS/ME and reflects on their limitations and perspectives in the process of developing new interventions.

scholarly journals Correction to: Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Do-Young Kim ◽  
Jin-Seok Lee ◽  
Samuel-Young Park ◽  
Soo-Jin Kim ◽  
Chang-Gue Son
Keyword(s):  
Systematic Review ◽  
Chronic Fatigue Syndrome ◽  
Randomized Controlled Trials ◽  
Chronic Fatigue ◽  
Myalgic Encephalomyelitis ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Fatigue Syndrome

An amendment to this paper has been published and can be accessed via the original article.

scholarly journals Systematic Review of Primary Outcome Measurements for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in Randomized Controlled Trials

2020 ◽  
Vol 9 (11) ◽  
pp. 3463
Author(s):  
Do-Young Kim ◽  
Jin-Seok Lee ◽  
Chang-Gue Son
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Randomized Controlled Trials ◽  
Primary Outcome ◽  
Chronic Fatigue ◽  
Myalgic Encephalomyelitis ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Fatigue Syndrome ◽  
Sf 36

Background: Due to its unknown etiology, the objective diagnosis and therapeutics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are still challenging. Generally, the patient-reported outcome (PRO) is the major strategy driving treatment response because the patient is the most important judge of whether changes are meaningful. Methods: In order to determine the overall characteristics of the main outcome measurement applied in clinical trials for CFS/ME, we systematically surveyed the literature using two electronic databases, PubMed and the Cochrane Library, throughout June 2020. We analyzed randomized controlled trials (RCTs) for CFS/ME focusing especially on main measurements. Results: Fifty-two RCTs out of a total 540 searched were selected according to eligibility criteria. Thirty-one RCTs (59.6%) used single primary outcome and others adapted ≥2 kinds of measurements. In total, 15 PRO-derived tools were adapted (50 RCTs; 96.2%) along with two behavioral measurements for adolescents (4 RCTs; 7.7%). The 36-item Short Form Health Survey (SF-36; 16 RCTs), Checklist Individual Strength (CIS; 14 RCTs), and Chalder Fatigue Questionnaire (CFQ; 11 RCTs) were most frequently used as the main outcomes. Since the first RCT in 1996, Clinical Global Impression (CGI) and SF-36 have been dominantly used each in the first and following decade (26.1% and 28.6%, respectively), while both CIS and Multidimensional Fatigue Inventory (MFI) have been the preferred instruments (21.4% each) in recent years (2016 to 2020). Conclusions: This review comprehensively provides the choice pattern of the assessment tools for interventions in RCTs for CFS/ME. Our data would be helpful practically in the design of clinical studies for CFS/ME-related therapeutic development.

Does Qigong Exercise Shape the Body, Mind and Spiritual Health for the Patients with Chronic Fatigue Syndrome (CFS): Waitlist Randomized Controlled Trial?

2013 ◽  
Author(s):  
Jessie S. M. Chan ◽  
S. M. Ng ◽  
Rainbow T. H. Ho ◽  
Bacon F. L. Ng ◽  
Eric T. C. Ziea ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Chronic Fatigue Syndrome ◽  
Controlled Trial ◽  
Chronic Fatigue ◽  
Spiritual Health ◽  
The Body ◽  
Randomized Controlled ◽  
Fatigue Syndrome
Sign in / Sign up

Export Citation Format

Share Document