Cobalt-catalyzed regioselective cycloaddition of unsymmetric diynes and nitriles to form substituted pyridines

2021 ◽  
Vol 516 ◽  
pp. 111956
Author(s):  
Jian-Shu Wang ◽  
Jun Ying ◽  
Xiao-Feng Wu
Keyword(s):  
Substituted Pyridines

scholarly journals Zn(II) Heteroleptic Halide Complexes with 2-Halopyridines: Features of Halogen Bonding in Solid State

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3393
Author(s):  
Mikhail A. Vershinin ◽  
Marianna I. Rakhmanova ◽  
Alexander S. Novikov ◽  
Maxim N. Sokolov ◽  
Sergey A. Adonin
Keyword(s):  
Solid State ◽  
Quantum Yield ◽  
Crystal Packing ◽  
Halogen Bonding ◽  
Molecular Complexes ◽  
Substituted Pyridines ◽  
Halide Complexes

Reactions between Zn(II) dihalides and 2-halogen-substituted pyridines 2-XPy result in a series of heteroleptic molecular complexes [(2-XPy)2ZnY2] (Y = Cl, X = Cl (1), Br (2), I (3); Y = Br, X = Cl (4), Br (5), I (6), Y = I, X = Cl (7), Br (8), and I (9)). Moreover, 1–7 are isostructural (triclinic), while 8 and 9 are monoclinic. In all cases, halogen bonding plays an important role in formation of crystal packing. Moreover, 1–9 demonstrate luminescence in asolid state; for the best emitting complexes, quantum yield (QY) exceeds 21%.

An Interlaboratory Evaluation of Five Pairs of Teratogens and Non-teratogens in Post-implantation Rat Embryo Culture

1996 ◽  
Vol 24 (2) ◽  
pp. 201-209
Author(s):  
Aldert H. Piersma ◽  
Rudolf Bechter ◽  
Nathalie Krafft ◽  
Beat P. Schmid ◽  
Jeanne Stadler ◽  
...  
Keyword(s):  
Embryo Culture ◽  
Developmental Toxicity ◽  
Culture Method ◽  
Rat Embryo ◽  
Good Correspondence ◽  
Substituted Pyridines ◽  
Phthalic Ester ◽  
Rat Embryo Culture ◽  
Post Implantation

The usefulness of the post-implantation rat embryo culture method in screening xenobiotic compounds for developmental toxicity was validated in four laboratories with five pairs of compounds. This approach was chosen to provide information on the interlaboratory reproducibility of the results and to compare the effects of chemical analogues in embryo culture. By testing analogous compounds which are known to have different embryotoxic potencies in vivo, the discriminating power of the embryo culture method for the compound classes under study could be optimally assessed. The classes selected for testing were triazole antifungals, phthalic ester metabolites, substituted pyridines, sulphonamides and methylated xanthines. In summary, it was possible to distinguish between the compounds in three of the pairs, it was not possible to discriminate between the compounds of one pair, and it was possible to discriminate between the compounds of the other pair at two out of the four laboratories. The embryo culture results generally show a good correspondence with the embryotoxic properties of the compounds tested in vivo, although the embryo culture method appeared to be able to discriminate between only some of the pairs of chemical analogues. Some discrepancies may have arisen among the laboratories, because of methodological differences. These results suggest that the post-implantation rat embryo culture method may be a useful tool for screening xenobiotics within classes of compounds known to interfere with embryogenesis during the period of development represented in culture.

Nature and Strength of the π‐Hole Chalcogen Bonded Complexes between Substituted Pyridines and SO 3 Molecule

2021 ◽  
Vol 6 (29) ◽  
pp. 7514-7524
Author(s):  
Sumitra Bhattarai ◽  
Dipankar Sutradhar ◽  
Therese Zeegers‐ Huyskens ◽  
Asit K. Chandra
Keyword(s):  
Substituted Pyridines ◽  
Bonded Complexes

ChemInform Abstract: Free Radicals in the Electrochemical Reduction of Some Mono- and Dinitro-Substituted Pyridines

ChemInform ◽  
2010 ◽  
Vol 25 (20) ◽  
pp. no-no
Author(s):  
J. STRADIN ◽  
R. GAVARS ◽  
L. BAUMANE ◽  
B. VIGANTE ◽  
G. DUBURS
Keyword(s):  
Free Radicals ◽  
Electrochemical Reduction ◽  
Substituted Pyridines

Metal-Free Synthesis of Highly Substituted Pyridines by Formal [2+2+2] Cycloaddition under Mild Conditions

2016 ◽  
Vol 128 (41) ◽  
pp. 13056-13059 ◽  
Author(s):  
Lan-Gui Xie ◽  
Saad Shaaban ◽  
Xiangyu Chen ◽  
Nuno Maulide
Keyword(s):  
Metal Free ◽  
Mild Conditions ◽  
Substituted Pyridines
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