Noninvasive determination of fiber orientation and tracking 2-dimensional deformation of human skin utilizing spatially resolved reflectance of infrared light measurement in vivo

Conformal modulus sensors (CMS) incorporate PZT nanoribbons as mechanical actuators and sensors to achieve reversible conformal contact with the human skin for non-invasive, in vivo measurements of skin modulus. An analytic model presented in this paper yields expressions that connect the sensor output voltage to the Young moduli of the epidermis and dermis, the thickness of the epidermis, as well as the material and geometrical parameters of the CMS device itself and its encapsulation layer. Results from the model agree well with in vitro experiments on bilayer structures of poly(dimethylsiloxane). These results provide a means to determine the skin moduli (epidermis and dermis) and the thickness of the epidermis from in vivo measurements of human skin.

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Spatially resolved spectroscopy for guiding margin delineation during human skin carcinomas resection: first clinical results on diffuse reflectance and autofluorescence spectra and in vivo skin optical properties

Biophotonics: Photonic Solutions for Better Health Care VI ◽

10.1117/12.2309516 ◽

2018 ◽

Cited By ~ 1

Author(s):

Prisca Rakotomanga ◽

Marine Amouroux ◽

Charles Soussen ◽

Frédéric Marchal ◽

Alain Delconte ◽

...

Keyword(s):

Optical Properties ◽

Human Skin ◽

Diffuse Reflectance ◽

Clinical Results ◽

Spatially Resolved ◽

Spatially Resolved Spectroscopy

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In vivo determination of the absorbance spectra of human skin

10.1117/12.483010 ◽

2002 ◽

Cited By ~ 1

Author(s):

Queyu Li ◽

Yang Wang ◽

Yong-Lin Zhang

Keyword(s):

Human Skin ◽

Absorbance Spectra

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Simultaneous Determination of Absorption Coefficients for Skin and Muscle Tissues Using Spatially Resolved Measurements

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.222.309 ◽

2011 ◽

Vol 222 ◽

pp. 309-312 ◽

Cited By ~ 1

Author(s):

Hiroshi Suzuki ◽

Masatsugu Niwayama ◽

Toshitaka Yamakawa ◽

Masaki Ohkubo ◽

Ryotaro Kime ◽

...

Keyword(s):

Near Infrared ◽

Absorption Coefficients ◽

Calculation Algorithm ◽

Spatially Resolved ◽

Muscle Tissues ◽

In Vivo Tests ◽

Deep Layers

We present a method for simultaneous measurement of optical absorption coefficients for skin (μas) and muscle (μam) tissues using spatially resolved near-infrared spectroscopy (SRS). A novel calculation algorithm was developed to determine the absorption coefficients of superficial and deep layers within a three-layered structure using Monte Carlo simulation. A method for measuring the skin and muscle absorption coefficients was proposed based on this algorithm. In vitro experiments with tissue-like phantom and in vivo tests were performed using the SRS system with four separate detectors. The results show that the absorption coefficients for both skin and muscle tissues were obtained accurately.

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