Reduced kinematic multiscale model for tissue engineering electrospun scaffolds

2022 ◽  
pp. 104214
Author(s):  
Daniel Enrique Caballero ◽  
Florencia Montini-Ballarin ◽  
Juan Manuel Gimenez ◽  
Nicolás Biocca ◽  
Nahuel Rull ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Multiscale Model ◽  
Electrospun Scaffolds

scholarly journals Harnessing the Topography of 3D Spongy-Like Electrospun Bundled Fibrous Scaffold via a Sharply Inclined Array Collector

Polymers ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1444 ◽  
Author(s):  
Sun Hee Cho ◽  
Jeong In Kim ◽  
Cheol Sang Kim ◽  
Chan Hee Park ◽  
In Gi Kim
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Three Dimensional ◽  
Living System ◽  
Pivotal Role ◽  
Skin Tissue ◽  
Target Tissue ◽  
Fibrous Scaffold ◽  
Electrospun Scaffolds ◽  
Directional Change

To date, many researchers have studied a considerable number of three-dimensional (3D) cotton-like electrospun scaffolds for tissue engineering, including the generation of bone, cartilage, and skin tissue. Although numerous 3D electrospun fibrous matrixes have been successfully developed, additional research is needed to produce 3D patterned and sophisticated structures. The development of 3D fibrous matrixes with patterned and sophisticated structures (FM-PSS) capable of mimicking the extracellular matrix (ECM) is important for advancing tissue engineering. Because modulating nano to microscale features of the 3D fibrous scaffold to control the ambient microenvironment of target tissue cells can play a pivotal role in inducing tissue morphogenesis after transplantation in a living system. To achieve this objective, the 3D FM-PSSs were successfully generated by the electrospinning using a directional change of the sharply inclined array collector. The 3D FM-PSSs overcome the current limitations of conventional electrospun cotton-type 3D matrixes of random fibers.

Evaluation of the effects of starch on polyhydroxybutyrate electrospun scaffolds for bone tissue engineering applications

2021 ◽  
Vol 191 ◽  
pp. 500-513
Author(s):  
Maryam Abdollahi Asl ◽  
Saeed Karbasi ◽  
Saeed Beigi-Boroujeni ◽  
Soheila Zamanlui Benisi ◽  
Mahdi Saeed
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Engineering Applications ◽  
Electrospun Scaffolds

Development of Bioresorbable Hydrophilic–Hydrophobic Electrospun Scaffolds for Neural Tissue Engineering

2016 ◽  
Vol 17 (10) ◽  
pp. 3172-3187 ◽  
Author(s):  
Luanda Chaves Lins ◽  
Florence Wianny ◽  
Sébastien Livi ◽  
Idalba Andreina Hidalgo ◽  
Colette Dehay ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Neural Tissue ◽  
Neural Tissue Engineering ◽  
Electrospun Scaffolds

scholarly journals Mesenchymal stem cell cultivation in electrospun scaffolds: mechanistic modeling for tissue engineering

2018 ◽  
Vol 44 (3) ◽  
pp. 245-271 ◽  
Author(s):  
Ágata Paim ◽  
Isabel C. Tessaro ◽  
Nilo S. M. Cardozo ◽  
Patricia Pranke
Keyword(s):  
Tissue Engineering ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Mechanistic Modeling ◽  
Cell Cultivation ◽  
Electrospun Scaffolds

Electrospun scaffolds for bone tissue engineering

2011 ◽  
Vol 95 (2) ◽  
pp. 69-80 ◽  
Author(s):  
Alberto Di Martino ◽  
Liliana Liverani ◽  
Alberto Rainer ◽  
Giuseppe Salvatore ◽  
Marcella Trombetta ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Electrospun Scaffolds

Platelet Activity of Coaxial Electrospun Scaffolds for Applications in Cardiovascular Tissue Engineering

2013 ◽  
Author(s):  
Valerie M. Merkle ◽  
Marcus Hutchinson ◽  
Phat L. Tran ◽  
Jawaad Sheriff ◽  
Danny Bluestein ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Endothelial Cell ◽  
Electrospun Nanofibers ◽  
Human Platelets ◽  
Vascular Endothelial ◽  
Platelet Activity ◽  
Cardiovascular Tissue ◽  
Electrospun Scaffolds ◽  
And Migration ◽  
Proliferation And Migration

A biocompatible scaffold is vital to implant device design, tissue engineering, and drug delivery. Previous work has shown smooth muscle cell and human umbilical vascular endothelial cell viability, adhesion, proliferation, and migration on coaxially electrospun scaffolds. For vascular applications, these electrospun scaffolds need to be non-thrombogenic, while simultaneously not completely inhibiting the platelets role in hemostasis and augmenting angiogenesis.[1] Therefore, platelet activity on electrospun scaffolds needs to be assessed. In this study, we fabricated coaxial electrospun nanofibers in both 1:1 and 3:1 (gelatin:polyvinyl alcohol, volumetric flow ratios), as well as scaffolds composed of either gelatin or polyvinyl alcohol (PVA). Platelet deposition on the electrospun scaffolds was measured. Furthermore, the activity of human platelets on the electrospun scaffolds was assessed using a modified prothrombinase assay.[2]

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