Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation

Metabolism ◽  
2020 ◽  
Vol 106 ◽  
pp. 154194 ◽  
Author(s):  
Joseph Skurski ◽  
Christie M. Penniman ◽  
Ramasatyaveni Geesala ◽  
Garima Dixit ◽  
Priyanjali Pulipati ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Adipose Tissue ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Diet Induced Obesity

scholarly journals Type II NKT Cells Stimulate Diet-Induced Obesity by Mediating Adipose Tissue Inflammation, Steatohepatitis and Insulin Resistance

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e30568 ◽  
Author(s):  
Masashi Satoh ◽  
Yasuhiro Andoh ◽  
Christopher Stuart Clingan ◽  
Hisako Ogura ◽  
Satoshi Fujii ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Adipose Tissue ◽  
Nkt Cells ◽  
Type Ii ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Diet Induced Obesity

scholarly journals IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance

Cytokine ◽  
2015 ◽  
Vol 75 (2) ◽  
pp. 280-290 ◽  
Author(s):  
Dov B. Ballak ◽  
Rinke Stienstra ◽  
Cees J. Tack ◽  
Charles A. Dinarello ◽  
Janna A. van Diepen
Keyword(s):  
Metabolic Disease ◽  
Insulin Resistance ◽  
Adipose Tissue ◽  
Family Members ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Disease Focus

scholarly journals Adipose tissue inflammation and metabolic dysfunction: a clinical perspective

2013 ◽  
Vol 15 (1) ◽  
Author(s):  
Charmaine S. Tam ◽  
Leanne M. Redman
Keyword(s):  
Insulin Resistance ◽  
Adipose Tissue ◽  
Low Grade ◽  
Metabolic Dysfunction ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Proinflammatory Mediators ◽  
Low Grade Inflammation

AbstractObesity is characterized by a state of chronic low-grade inflammation due to increased immune cells, specifically infiltrated macrophages into adipose tissue, which in turn secrete a range of proinflammatory mediators. This nonselective low-grade inflammation of adipose tissue is systemic in nature and can impair insulin signaling pathways, thus, increasing the risk of developing insulin resistance and type 2 diabetes. The aim of this review is to provide an update on clinical studies examining the role of adipose tissue in the development of obesity-associated complications in humans. We will discuss adipose tissue inflammation during different scenarios of energy imbalance and metabolic dysfunction including obesity and overfeeding, weight loss by calorie restriction or bariatric surgery, and conditions of insulin resistance (diabetes, polycystic ovarian syndrome).

scholarly journals Erythropoietin Signaling: A Novel Regulator of White Adipose Tissue Inflammation During Diet-Induced Obesity

Diabetes ◽  
2014 ◽  
Vol 63 (7) ◽  
pp. 2415-2431 ◽  
Author(s):  
M. Alnaeeli ◽  
B. M. Raaka ◽  
O. Gavrilova ◽  
R. Teng ◽  
T. Chanturiya ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
White Adipose Tissue ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Diet Induced Obesity

scholarly journals Glucose-6-Phosphate Dehydrogenase Deficiency Improves Insulin Resistance With Reduced Adipose Tissue Inflammation in Obesity

Diabetes ◽  
2016 ◽  
Vol 65 (9) ◽  
pp. 2624-2638 ◽  
Author(s):  
Mira Ham ◽  
Sung Sik Choe ◽  
Kyung Cheul Shin ◽  
Goun Choi ◽  
Ji-Won Kim ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Adipose Tissue ◽  
Dehydrogenase Deficiency ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Glucose 6 Phosphate Dehydrogenase
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