Dengue virus infection-enhancing and neutralizing antibody balance in children of the Philippines and Indonesia

2012 ◽  
Vol 14 (13) ◽  
pp. 1152-1159 ◽  
Author(s):  
Atsushi Yamanaka ◽  
Yuko Tabuchi ◽  
Kris C. Mulyatno ◽  
Helen Susilowati ◽  
Eryk Hendrianto ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Neutralizing Antibody ◽  
The Philippines ◽  
Dengue Virus Infection

scholarly journals Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection

2021 ◽  
Vol 2 (5) ◽  
pp. 100278
Author(s):  
Angeline Rouers ◽  
Melissa Hui Yen Chng ◽  
Bernett Lee ◽  
Menaka P. Rajapakse ◽  
Kaval Kaur ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Disease Severity ◽  
Immune Cell ◽  
Neutralizing Antibody ◽  
Dengue Virus Infection ◽  
Antibody Titers ◽  
Cell Phenotypes

scholarly journals Human Serum With High Neutralizing Antibody Titers Against Both Zika and Dengue Virus Shows Delayed In Vitro Antibody-Dependent Enhancement of Dengue Virus Infection

2018 ◽  
Vol 5 (7) ◽  
Author(s):  
William G Valiant ◽  
Tahaniyat Lalani ◽  
Heather C Yun ◽  
Anjali Kunz ◽  
Timothy H Burgess ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Zika Virus ◽  
Neutralizing Antibodies ◽  
Dengue Infection ◽  
Neutralizing Antibody ◽  
Naive Subject ◽  
Dengue Virus Infection ◽  
Antibody Titers

Abstract Zika virus infection in a dengue virus–naïve subject was associated with the induction of high levels of cross-reactive binding antibodies. These responses were, however, largely non-neutralizing and displayed a capacity to enhance dengue infection in vitro at significantly low dilution (1:10). In contrast, a subject who had high levels of neutralizing antibodies against both dengue and Zika viruses enhanced infection at a dilution of 1:10 000. These results suggest that high levels of dengue cross-neutralizing antibodies could potentially prevent the enhancement of dengue infection in Zika virus–convalescent individuals.

scholarly journals Incidence of Dengue Virus Infection in Adults and Children in a Prospective Longitudinal Cohort in the Philippines

2016 ◽  
Vol 10 (2) ◽  
pp. e0004337 ◽  
Author(s):  
Maria Theresa Alera ◽  
Anon Srikiatkhachorn ◽  
John Mark Velasco ◽  
Ilya A. Tac-An ◽  
Catherine B. Lago ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
The Philippines ◽  
Dengue Virus Infection ◽  
Longitudinal Cohort ◽  
Adults And Children ◽  
Prospective Longitudinal ◽  
Prospective Longitudinal Cohort
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