Sustainable valorization of papaya peels for thrombolytic cysteine protease isolation by ultrasound assisted disruptive liquid phase microextraction with task specific switchable natural deep eutectic solvents

2021 ◽  
pp. 107118
Author(s):  
Harish Babu Balaraman ◽  
Gayatri Viswanathan ◽  
Ramya Muniasamy ◽  
T. Gayatri ◽  
Senthil Kumar Rathnasamy
Keyword(s):  
Liquid Phase ◽  
Cysteine Protease ◽  
Deep Eutectic Solvents ◽  
Liquid Phase Microextraction ◽  
Natural Deep Eutectic Solvents ◽  
Ultrasound Assisted

Ultrasound-assisted liquid-phase microextraction based on a nanostructured supramolecular solvent

2013 ◽  
Vol 405 (12) ◽  
pp. 4235-4243 ◽  
Author(s):  
Morteza Moradi ◽  
Yadollah Yamini ◽  
Moslem Tayyebi ◽  
Hamid Asiabi
Keyword(s):  
Liquid Phase ◽  
Liquid Phase Microextraction ◽  
Supramolecular Solvent ◽  
Ultrasound Assisted

scholarly journals Application of Hollow Fibre-Liquid Phase Microextraction Technique for Isolation and Pre-Concentration of Pharmaceuticals in Water

Membranes ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 311
Author(s):  
Lawrence Mzukisi Madikizela ◽  
Vusumzi Emmanuel Pakade ◽  
Somandla Ncube ◽  
Hlanganani Tutu ◽  
Luke Chimuka
Keyword(s):  
Liquid Phase ◽  
Solid Phase ◽  
Deep Eutectic Solvents ◽  
Enrichment Factors ◽  
Hollow Fibre ◽  
Phase System ◽  
Phase Extraction ◽  
Liquid Phase Microextraction ◽  
Three Phase ◽  
Set Up

In this article, a comprehensive review of applications of the hollow fibre-liquid phase microextraction (HF-LPME) for the isolation and pre-concentration of pharmaceuticals in water samples is presented. HF-LPME is simple, affordable, selective, and sensitive with high enrichment factors of up to 27,000-fold reported for pharmaceutical analysis. Both configurations (two- and three-phase extraction systems) of HF-LPME have been applied in the extraction of pharmaceuticals from water, with the three-phase system being more prominent. When compared to most common sample preparation techniques such as solid phase extraction, HF-LPME is a greener analytical chemistry process due to reduced solvent consumption, miniaturization, and the ability to automate. However, the automation comes at an added cost related to instrumental set-up, but a reduced cost is associated with lower reagent consumption as well as shortened overall workload and time. Currently, many researchers are investigating ionic liquids and deep eutectic solvents as environmentally friendly chemicals that could lead to full classification of HF-LPME as a green analytical procedure.

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