Fe3O4@silica sulfuric acid nanoparticles: An efficient reusable nanomagnetic catalyst as potent solid acid for one-pot solvent-free synthesis of indazolo[2,1-b]phthalazine-triones and pyrazolo[1,2-b]phthalazine-diones

2013 ◽  
Vol 373 ◽  
pp. 46-54 ◽  
Author(s):  
Ali Reza Kiasat ◽  
Jamal Davarpanah
Keyword(s):  
Sulfuric Acid ◽  
Solid Acid ◽  
Solvent Free ◽  
Silica Sulfuric Acid ◽  
One Pot ◽  
Solvent Free Synthesis

scholarly journals Silica sulfuric acid: a reusable solid catalyst for one pot synthesis of densely substituted pyrrole-fused isocoumarins under solvent-free conditions

2013 ◽  
Vol 9 ◽  
pp. 2344-2353 ◽  
Author(s):  
Sudipta Pathak ◽  
Kamalesh Debnath ◽  
Animesh Pramanik
Keyword(s):  
Sulfuric Acid ◽  
Low Cost ◽  
Solvent Free ◽  
Primary Amines ◽  
Solid Catalyst ◽  
Silica Sulfuric Acid ◽  
Reaction Conditions ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Solvent Free Reaction

A convenient and efficient methodology for the synthesis of densely substituted pyrrole-fused isocoumarins, which employs solid-supported silica sulfuric acid (SSA) as catalyst, has been developed. When the mixture of ninhydrin adducts of acetylacetone/ethyl acetoacetate and primary amines was heated on the solid surface of SSA under solvent-free conditions, the pyrrole-fused isocoumarins were formed in good yields. This synthetic method has several advantages such as the employment of solvent-free reaction conditions without the use of any toxic reagents and metal catalysts, the ease of product isolation, the use of a recyclable catalyst, the low cost, the easy availability of the starting materials, and the excellent yields of products.

scholarly journals Silica Sulfuric Acid as an Efficient Heterogeneous Catalyst for the Solvent-Free Synthesis of 1-Substituted 1H-1,2,3,4-Tetrazoles

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Davood Habibi ◽  
Hiva Nabavi ◽  
Mahmoud Nasrollahzadeh
Keyword(s):  
Sulfuric Acid ◽  
Heterogeneous Catalyst ◽  
Sodium Azide ◽  
Solvent Free ◽  
Triethyl Orthoformate ◽  
Primary Amines ◽  
Silica Sulfuric Acid ◽  
Solvent Free Conditions ◽  
Solvent Free Synthesis ◽  
Efficient Heterogeneous Catalyst

Silica sulfuric acid (SSA) was found to be an efficient heterogeneous catalyst for the synthesis of 1-substituted 1H-1,2,3,4-tetrazoles from the reaction of primary amines with triethyl orthoformate and sodium azide under thermal and solvent-free conditions.

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