Common cutaneous infections

Medicine ◽  
2021 ◽  
Author(s):  
Roberto Corso ◽  
Rachael Morris Jones
Keyword(s):  
2021 ◽  
Vol 10 (5) ◽  
pp. 1040
Author(s):  
Jo L. W. Lambert ◽  
Sofie De Schepper ◽  
Reinhart Speeckaert

The biologic era has greatly improved the treatment of Crohn’s disease and ulcerative colitis. Biologics can however induce a wide variety of skin eruptions, especially those targeting the TNF-α and Th17 pathway. These include infusion reactions, eczema, psoriasis, lupus, alopecia areata, vitiligo, lichenoid reactions, granulomatous disorders, vasculitis, skin cancer, and cutaneous infections. It is important to recognize these conditions as treatment-induced adverse reactions and adapt the treatment strategy accordingly. Some conditions can be treated topically while others require cessation or switch of the biological therapy. TNF-α antagonists have the highest rate adverse skin eruptions followed by ustekinumab and anti-integrin receptor blockers. In this review, we provide an overview of the most common skin eruptions which can be encountered in clinical practice when treating IBD (Inflammatory bowel disease) patients and propose a therapeutic approach for each condition.


2008 ◽  
Vol 21 (3) ◽  
pp. 153-153
Author(s):  
Jana Hercogova
Keyword(s):  

2011 ◽  
Vol 55 (4) ◽  
pp. 1734-1739 ◽  
Author(s):  
Jérôme Robert ◽  
Anne Tristan ◽  
Laurent Cavalié ◽  
Jean-Winoc Decousser ◽  
Michèle Bes ◽  
...  

ABSTRACTThe epidemiology of community-acquired methicillin-resistantStaphylococcus aureus(CA-MRSA) differs from country to country. We assess the features of the ST80 European clone, which is the most prevalent PVL-positive CA-MRSA clone in Europe, and the TSST-1 ST5 clone that was recently described in France. In 2008, all MRSA strains susceptible to fluoroquinolones and gentamicin and resistant to fusidic acid that were isolated in 104 French laboratories were characterized usingagralleles,spatyping, and the staphylococcal cassette chromosomemecelement and PCR profiling of 21 toxin genes. Three phenotypes were defined: (i) kanamycin resistant, associated with the ST80 clone; (ii) kanamycin and tobramycin resistant, associated with the ST5 clone; and (iii) aminoglycoside susceptible, which was less frequently associated with the ST5 clone. Among the 7,253 MRSA strains isolated, 91 (1.3%) were ST80 CA-MRSA (89 phenotype 1) and 190 (2.6%) were ST5 CA-MRSA (146 phenotype 2, 42 phenotype 3). Compared to the latter, ST80 CA-MRSAs were more likely to be community acquired (80% versus 46%) and found in young patients (median age, 26.0 years versus 49.5 years) with deep cutaneous infections (48% versus 6%). They were less likely to be tetracycline susceptible (22% versus 85%) and to be isolated from respiratory infections (6% versus 27%). The TSST-1 ST5 clone has rapidly emerged in France and has become even more prevalent than the ST80 European clone, whose prevalence has remained stable. The epidemiological and clinical patterns of the two clones differ drastically. Given the low prevalence of both among all staphylococcal infections, no modification of antibiotic recommendations is required yet.


2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Daria Marley Kemp ◽  
Anusha G. Govind ◽  
Jun Kang ◽  
Caroline C. Brugger ◽  
Young C. Kauh

Mycobacterium chelonae is a rapidly growing mycobacterium found in water and soil that can cause local cutaneous infections in immunocompetent hosts but more frequently affects immunocompromised patients. Typically, patients will present with painful subcutaneous nodules of the joints or soft tissues from traumatic inoculation. However, exhibiting a sporotrichoid-like pattern of these nodules is uncommon. Herein, we report a case of sporotrichoid-like distribution of cutaneous Mycobacterium chelonae in a patient with systemic lupus erythematosus on significant immunosuppressive medications. Clinicians treating immunocompromised patients should be cognizant of their propensity to develop unusual infections and atypical presentations.


Author(s):  
Fouzia Rhazi Filali ◽  
Fatima-zahra Ennacirie ◽  
Abdelilah Rahou

ABSTRACTAn ethnobotanical study of medicinal plants was carried in the province of Sidi Kacem (Morocco), whose objective is to make an inventory of medicinalplants used in traditional therapy against respiratory, digestive, and cutaneous infections; also to describe their mode of use practiced by the localpopulation. The tool of the study was a questionnaire completed by 200 citizens of four investigated areas, determined by the stratified samplingtechniques, 40% practiced phytotherapy. The survey consists of a section on the informant, and another is interested in plants used by the population.The analysis of information has established a catalog of 73 species identified with their use of frequencies, partly used and the method of preparation.They belong to 39 families; the most dominant are Lamiaceae, Apiaceae, and Asteraceae. The leaves are the most used part in decoction to treat thethree types of infection mentioned above. These results allow us to create a database about this region’s plants characteristic. They will be useful toestablish further studies on their chemical properties and biological activities.Keywords: Province of Sidi Kacem (Morocco), Phytotherapy, Ethnobotanical survey, Infections, Catalogue of plants.


2018 ◽  
Vol 36 (2) ◽  
pp. 188-196 ◽  
Author(s):  
Maria Cristina Ribeiro de Castro ◽  
Marcia Ramos-e-Silva

2018 ◽  
Vol 129 (4) ◽  
pp. 721-732 ◽  
Author(s):  

Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Complications in pediatric regional anesthesia are rare, so a large sample size is necessary to quantify risk. The Pediatric Regional Anesthesia Network contains data on more than 100,000 blocks administered at more than 20 children’s hospitals. This study analyzed the risk of major complications associated with regional anesthesia in children. Methods This is a prospective, observational study of routine clinical practice. Data were collected on every regional block placed by an anesthesiologist at participating institutions and were uploaded to a secure database. The data were audited at multiple points for accuracy. Results There were no permanent neurologic deficits reported (95% CI, 0 to 0.4:10,000). The risk of transient neurologic deficit was 2.4:10,000 (95% CI, 1.6 to 3.6:10,000) and was not different between peripheral and neuraxial blocks. The risk of severe local anesthetic systemic toxicity was 0.76:10,000 (95% CI, 0.3 to 1.6:10,000); the majority of cases occurred in infants. There was one epidural abscess reported (0.76:10,000, 95% CI, 0 to 4.8:10,000). The incidence of cutaneous infections was 0.5% (53:10,000, 95% CI, 43 to 64:10,000). There were no hematomas associated with neuraxial catheters (95% CI, 0 to 3.5:10,000), but one epidural hematoma occurred with a paravertebral catheter. No additional risk was observed with placing blocks under general anesthesia. The most common adverse events were benign catheter-related failures (4%). Conclusions The data from this study demonstrate a level of safety in pediatric regional anesthesia that is comparable to adult practice and confirms the safety of placing blocks under general anesthesia in children.


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