scholarly journals PHD fingers in human diseases: Disorders arising from misinterpreting epigenetic marks

2008 ◽  
Vol 647 (1-2) ◽  
pp. 3-12 ◽  
Author(s):  
Lindsey A. Baker ◽  
C. David Allis ◽  
Gang G. Wang
Keyword(s):  
Human Diseases ◽  
Epigenetic Marks

scholarly journals The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium

2019 ◽  
Vol 5 (7) ◽  
pp. eaaw6507 ◽  
Author(s):  
John S. Satterlee ◽  
Lisa H. Chadwick ◽  
Frederick L. Tyson ◽  
Kim McAllister ◽  
Jill Beaver ◽  
...  
Keyword(s):  
Lessons Learned ◽  
Human Diseases ◽  
Human Tissues ◽  
Epigenetic Marks ◽  
Common Fund ◽  
Nih Roadmap ◽  
Tools And Methods

The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort.

Experimental Amyloidosis Induced by Immune Complex

1971 ◽  
Vol 29 ◽  
pp. 582-583
Author(s):  
A. Kawaoi
Keyword(s):  
Immune Complex ◽  
Systemic Amyloidosis ◽  
Human Diseases ◽  
Experimental Amyloidosis ◽  
Freund’S Complete Adjuvant ◽  
Freund's Complete Adjuvant ◽  
Immunological Approach ◽  
Experimentally Induced

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.

Bizarre models for human diseases

Nature ◽  
2010 ◽  
Author(s):  
Janelle Weaver
Keyword(s):  
Human Diseases

321-LB: The Link between Obesity and Changes in Epigenetic Marks in Adipose Tissue—In Vivo Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 321-LB
Author(s):  
ANETA ALAMA ◽  
DOROTA PAWE?KA ◽  
ANETA MYSZCZYSZYN ◽  
MALGORZATA MALODOBRA-MAZUR
Keyword(s):  
Adipose Tissue ◽  
In Vivo Study ◽  
Epigenetic Marks

Key Topics in Human Diseases for Dental Students

2005 ◽  
Author(s):  
Prasanna Sooriakumaran ◽  
Channa Jayasena ◽  
Professor Crispian Scully
Keyword(s):  
Dental Students ◽  
Human Diseases ◽  
Key Topics

Advance in genome analysis for human diseases

2009 ◽  
Vol 22 (2) ◽  
pp. 126-130
Author(s):  
Naomichi Matsumoto
Keyword(s):  
Genome Analysis ◽  
Human Diseases
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