Abstract
Background: Primary cardiac osteosarcoma is an uncommon condition, which is challenging to diagnose, and rarely reported.Case presentation: Here, we present a previously healthy 27-year-old patient referred to our hospital with a long-term fever. Echocardiography and thoracic computed tomography (CT) presented two masses in the left atrium (LA) and left ventricle (LV), and surgical excision of the masses revealed cardiac high-grade osteosarcoma. Unfortunately, the left ventricular tumor recurred three months later, and the patient was administered periodic chemotherapy. Then, chest CT showed that the left ventricle was almost occupied by the tumor and also involved the left ventricular outflow tract, the left atrial appendage mass increased significantly, and multiple metastatic small nodules appeared in both lungs.The patient is still in follow-up.Conclusions: The prevalence of primary cardiac osteosarcoma is very low and did not involve LA and LV simultaneously. This patient was hospitalized in our hospital complaining of a long-term fever of unknown origin, which has never been reported in the previous literatures. Our case report findings suggest that primary cardiac osteosarcoma should not be ignored in the differential diagnosis of fever of unknown origin.
Intravascular Large B Cell Lymphoma Presenting as Fever of Unknown Origin and Diagnosed by Random Skin Biopsies: A Case Report and Literature Review
