Resting-state functional connectivity networks associated with fatigue in multiple sclerosis with early age onset

2019 ◽  
Vol 31 ◽  
pp. 101-105 ◽  
Author(s):  
Patricia Stefancin ◽  
Sindhuja T Govindarajan ◽  
Lauren Krupp ◽  
Leigh Charvet ◽  
Timothy Q Duong
Keyword(s):  
Multiple Sclerosis ◽  
Functional Connectivity ◽  
Resting State ◽  
Early Age ◽  
Resting State Functional Connectivity

scholarly journals Sex Differences in Resting-State Functional Connectivity in Multiple Sclerosis

2013 ◽  
Vol 34 (12) ◽  
pp. 2304-2311 ◽  
Author(s):  
K.A. Koenig ◽  
M.J. Lowe ◽  
J. Lin ◽  
K.E. Sakaie ◽  
L. Stone ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Sex Differences ◽  
Functional Connectivity ◽  
Resting State ◽  
Resting State Functional Connectivity

Resting-state functional connectivity in multiple sclerosis: An examination of group differences and individual differences

2013 ◽  
Vol 51 (13) ◽  
pp. 2918-2929 ◽  
Author(s):  
Alisha L. Janssen ◽  
Aaron Boster ◽  
Beth A. Patterson ◽  
Amir Abduljalil ◽  
Ruchika Shaurya Prakash
Keyword(s):  
Multiple Sclerosis ◽  
Individual Differences ◽  
Functional Connectivity ◽  
Resting State ◽  
Group Differences ◽  
Resting State Functional Connectivity

scholarly journals Anterior Insular Resting‐State Functional Connectivity is Related to Cognitive Reserve in Multiple Sclerosis

2020 ◽  
Author(s):  
Bernardo Canedo Bizzo ◽  
Tiago Arruda‐Sanchez ◽  
Sean M Tobyne ◽  
John Daniel Bireley ◽  
Michael Howard Lev ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Functional Connectivity ◽  
Resting State ◽  
Cognitive Reserve ◽  
Resting State Functional Connectivity

Fatigue in multiple sclerosis: The contribution of resting-state functional connectivity reorganization

2017 ◽  
Vol 24 (13) ◽  
pp. 1696-1705 ◽  
Author(s):  
Alvino Bisecco ◽  
Federica Di Nardo ◽  
Renato Docimo ◽  
Giuseppina Caiazzo ◽  
Alessandro d’Ambrosio ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Regression Analysis ◽  
Functional Connectivity ◽  
Motor Cortex ◽  
Resting State ◽  
Primary Motor Cortex ◽  
Linear Regression Analysis ◽  
Posterior Cingulate Cortex ◽  
Resting State Functional Connectivity ◽  
Sensorimotor Network

Objectives: To investigate resting-state functional connectivity (RS-FC) of the default-mode network (DMN) and of sensorimotor network (SMN) network in relapsing remitting (RR) multiple sclerosis (MS) patients with fatigue (F) and without fatigue(NF). Methods: In all, 59 RRMS patients and 29 healthy controls (HC) underwent magnetic resonance imaging (MRI) protocol including resting-state fMRI (RS-fMRI). Functional connectivity of the DMN and SMN was evaluated by independent component analysis (ICA). A linear regression analysis was performed to explore whether fatigue was mainly driven by changes observed in the DMN or in the SMN. Regional gray matter atrophy was assessed by voxel-based morphometry (VBM). Results: Compared to HC, F-MS patients showed a stronger RS-FC in the posterior cingulate cortex (PCC) and a reduced RS-FC in the anterior cingulated cortex (ACC) of the DMN. F-MS patients, compared to NF-MS patients, revealed (1) an increased RS-FC in the PCC and a reduced RS-FC in the ACC of the DMN and (2) an increased RS-FC in the primary motor cortex and in the supplementary motor cortex of the SMN. The regression analysis suggested that fatigue is mainly driven by RS-FC changes of the DMN. Conclusions: Fatigue in RRMS is mainly associated to a functional rearrangement of non-motor RS networks.

scholarly journals Cognitive Dysfunction in Early Multiple Sclerosis: Altered Centrality Derived from Resting-State Functional Connectivity Using Magneto-Encephalography

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
pp. e42087 ◽  
Author(s):  
Martin Hardmeier ◽  
Menno M. Schoonheim ◽  
Jeroen J. G. Geurts ◽  
Arjan Hillebrand ◽  
Chris H. Polman ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Functional Connectivity ◽  
Cognitive Dysfunction ◽  
Resting State ◽  
Resting State Functional Connectivity

scholarly journals Multiple Sclerosis: Changes in Thalamic Resting-State Functional Connectivity Induced by a Home-based Cognitive Rehabilitation Program

Radiology ◽  
2016 ◽  
Vol 280 (1) ◽  
pp. 202-211 ◽  
Author(s):  
Laura De Giglio ◽  
Francesca Tona ◽  
Francesca De Luca ◽  
Nikolaos Petsas ◽  
Luca Prosperini ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Functional Connectivity ◽  
Resting State ◽  
Cognitive Rehabilitation ◽  
Rehabilitation Program ◽  
Resting State Functional Connectivity ◽  
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