Calcium phosphate coated Keratin–PCL scaffolds for potential bone tissue regeneration

2015 ◽  
Vol 49 ◽  
pp. 746-753 ◽  
Author(s):  
Xinxin Zhao ◽  
Yuan Siang Lui ◽  
Caleb Kai Chuen Choo ◽  
Wan Ting Sow ◽  
Charlotte Liwen Huang ◽  
...  
Biomaterials ◽  
2010 ◽  
Vol 31 (6) ◽  
pp. 1260-1269 ◽  
Author(s):  
Jie Wei ◽  
Junfeng Jia ◽  
Fan Wu ◽  
Shicheng Wei ◽  
Huanjun Zhou ◽  
...  

2015 ◽  
Vol 3 (43) ◽  
pp. 8558-8566 ◽  
Author(s):  
Nan Li ◽  
Chuan Jiang ◽  
Xingdi Zhang ◽  
Xinfeng Gu ◽  
Jingwei Zhang ◽  
...  

An rhBMP-2/MBG/CPC scaffold is beneficial for rapid bone tissue regeneration in the early stage.


2019 ◽  
Vol 5 (11) ◽  
pp. 6054-6062 ◽  
Author(s):  
Farzad Foroutan ◽  
Jamie McGuire ◽  
Priyanka Gupta ◽  
Athanasios Nikolaou ◽  
Benjamin A. Kyffin ◽  
...  

Author(s):  
Torbjörn Mellgren ◽  
Amela Trbakovic ◽  
Andreas Thor ◽  
Stina Ekman ◽  
Cecilia Ley ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (19) ◽  
pp. 5860
Author(s):  
Syama Santhakumar ◽  
Ayako Oyane ◽  
Maki Nakamura ◽  
Yuto Yoshino ◽  
Mohammed Katib Alruwaili ◽  
...  

Surface-mineralized collagen sponges have attracted much attention as scaffolds for bone tissue engineering. Recently, we developed amorphous calcium phosphate (ACP) and low-crystalline apatite coating processes on collagen sponges. In the present study, we applied these coating processes to granular collagen sponges (referred to as Col) to compare the bone tissue regeneration capabilities of ACP-coated and apatite-coated Col (referred to as Col-ACP and Col-Ap, respectively) using a rat cranial bone defect model. According to micro-CT and histological analyses, Col-Ap enhanced bone tissue regeneration compared to Col, whereas Col-ACP did not. These results not only demonstrated the superior bone tissue regeneration capability of Col-Ap, but also indicated limitations of the in vitro simulated body fluid (SBF) test used in our previous study. Despite the apatite-forming ability of Col-ACP in SBF, it was ineffective in improving bone tissue regeneration in vivo, unlike Col-Ap, most likely due to the quick resorption of the ACP coating in the defect site. The present results clarified the importance of the coating stability in vivo and revealed that the low-crystalline apatite coating was more beneficial than the ACP coating in the fabrication of surface-mineralized collagen sponges for use as bone tissue engineering scaffolds.


2016 ◽  
Vol 42 (2) ◽  
pp. 3177-3189 ◽  
Author(s):  
Rui Liu ◽  
XiXi Wu ◽  
Jiyan Li ◽  
Xujie Liu ◽  
Zhi Huang ◽  
...  

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