Development of a PCL-silica nanoparticles composite membrane for Guided Bone Regeneration

2018 ◽  
Vol 85 ◽  
pp. 154-161 ◽  
Author(s):  
Antonio G.B. Castro ◽  
Mani Diba ◽  
Monique Kersten ◽  
John A. Jansen ◽  
Jeroen J.J.P. van den Beucken ◽  
...  
2014 ◽  
Vol 606 ◽  
pp. 47-50
Author(s):  
Nur Najiha Saarani ◽  
K. Jamuna-Thevi ◽  
Ida Idayu Muhammad ◽  
Hendra Hermawan

Guided Bone Regeneration (GBR) membrane is used as a barrier to prevent soft tissue ingrowth and to encourage bone regeneration through cellular exclusion. This study aims to assess antibacterial properties of recently developed three-layered poly(lactic-co-glycolic acid) (PLGA) /lauric acid (LA) composite membrane towards Staphylococcus aureus. One of the outmost layers of three-layered membrane was incorporated with 1-3 wt% of LA. The composite membrane was developed using thermally induced phase separation/solvent leaching technique. SEM results shows formation of PLGA matrix with smaller pores by the addition of 1 wt% LA compared with pure PLGA membrane. Samples of 1.7 cm diameter disk containing 1, 2 and 3 wt% of lauric acid were tested and pure membrane without lauric acid was used as a control. Results showed that the zones of inhibition were 2.3 cm and 2.5 cm for the 2 wt% and 3 wt% LA-containing membranes, respectively. However, 1 wt% LA-containing membrane observed to have no inhibition at all, indicating that increasing concentration of LA has significant inhibition against Staphylococcus aureus. The 3 wt% LA composition will be used in the mechanically optimized membranes for degradation studies in future works.


2011 ◽  
Vol 22 (1-3) ◽  
pp. 263-275 ◽  
Author(s):  
Jidong Li ◽  
Yi Man ◽  
Yi Zuo ◽  
Li Zhang ◽  
Cui Huang ◽  
...  

2019 ◽  
Vol 7 (20) ◽  
pp. 3279-3290 ◽  
Author(s):  
Shuang Yu ◽  
Jun Shi ◽  
Yutong Liu ◽  
Jiawen Si ◽  
Yuan Yuan ◽  
...  

A PEGS/β-TCP composite membrane was fabricated by a simple prepolymer mixing-in situ crosslinking method for guided bone regeneration.


2013 ◽  
Vol 102 (9) ◽  
pp. 2911-2917 ◽  
Author(s):  
Jun Cui ◽  
Jie Liang ◽  
Yong Wen ◽  
Xiaoning Sun ◽  
Tiejun Li ◽  
...  

2008 ◽  
Vol 12 (2) ◽  
pp. 98-101
Author(s):  
J. D. Li ◽  
Y. Zuo ◽  
X. M. Cheng ◽  
C. Huang ◽  
Y. B. Li

2014 ◽  
Vol 43 ◽  
pp. 253-263 ◽  
Author(s):  
Kalitheertha Jamuna-Thevi ◽  
Nur Najiha Saarani ◽  
Mohamed Rafiq Abdul Kadir ◽  
Hendra Hermawan

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