Synthesis and characterization of a molecularly imprinted polymer (MIP) for solid-phase extraction of the antidiabetic gliclazide from human plasma

2020 ◽  
Vol 116 ◽  
pp. 111191 ◽  
Author(s):  
Ingrid Vasconcelos ◽  
Pedro Henrique Reis da Silva ◽  
Derick Rodrigues Davila Dias ◽  
Maria Betânia de Freitas Marques ◽  
Wagner da Nova Mussel ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Molecularly Imprinted Polymer ◽  
Solid Phase ◽  
Synthesis And Characterization ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

Development of a molecularly imprinted polymer based solid-phase extraction of local anaesthetics from human plasma

2004 ◽  
Vol 526 (2) ◽  
pp. 147-154 ◽  
Author(s):  
Lars I. Andersson ◽  
Emilia Hardenborg ◽  
Maria Sandberg-Ställ ◽  
Kristina Möller ◽  
Johan Henriksson ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Molecularly Imprinted Polymer ◽  
Solid Phase ◽  
Local Anaesthetics ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

scholarly journals Preparation and utilization of a molecularly imprinted polymer for solid phase extraction of tramadol

2010 ◽  
Vol 8 (4) ◽  
pp. 861-869 ◽  
Author(s):  
Saman Azodi-Deilami ◽  
Majid Abdouss ◽  
Seyed Hasani
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Molecularly Imprinted Polymer ◽  
Solid Phase ◽  
Extraction Procedure ◽  
Molecular Structures ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Human Plasma And Urine

AbstractIn this paper, a highly selective molecularly imprinted polymer (MIP) for tramadol hydrochloride, a drug used to treat moderate to severe pain, was prepared and its use as solid-phase extraction (SPE) sorbent was demonstrated. The molecularly imprinted solid-phase extraction procedure followed by high performance liquid chromatography with ultraviolet detector (MISPE-HPLC) was developed for selective extraction and determination of tramadol in human plasma and urine. The optimal conditions for molecularly imprinted solid-phase extraction (MISPE) consisted of conditioning with 1 mL methanol and 1 mL of deionized water at neutral pH, loading of tramadol sample (50 µg L−1) at pH 7.5, washing using 1 mL acetone and elution with 3 × 1 mL of 10% (v/v) acetic acid in methanol. The MIP selectivity was evaluated by checking several substances with similar molecular structures to that of tramadol. Results from the HPLC analyses showed that the calibration curve of tramadol (using MIP from human plasma and urine) is linear in the ranges of 6–100 and 3–120 µg L−1 with good precisions (1.9% and 2.9% for 5.0 µg L−1), respectively. The recoveries for plasma and urine samples were higher than 81%.

Molecularly imprinted polymer for solid-phase extraction of ephedrine and analogs from human plasma

2009 ◽  
Vol 32 (7) ◽  
pp. 1036-1042 ◽  
Author(s):  
Martina Lasáková ◽  
Didier Thiébaut ◽  
Pavel Jandera ◽  
Valérie Pichon
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Molecularly Imprinted Polymer ◽  
Solid Phase ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

Application of the response surface methodology in the optimization of modified molecularly imprinted polymer based pipette-tip micro-solid phase extraction for spectrophotometric determination of nicotine in seawater and human plasma

2019 ◽  
Vol 11 (42) ◽  
pp. 5405-5412 ◽  
Author(s):  
Sayyed Hossein Hashemi ◽  
Fateme Keykha
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Molecularly Imprinted Polymer ◽  
Solid Phase ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Spectrophotometric Detection ◽  
Molecularly Imprinted ◽  
Pipette Tip

In this paper, a novel molecularly imprinted polymer/zinc oxide (MIP/ZnO) was synthesized and applied as an adsorbent for pipette-tip micro-solid phase extraction (MIP/ZnO PT-μSPE) of nicotine from seawater and human plasma followed by its spectrophotometric detection.

Molecularly imprinted polymer for determination of lumefantrine in human plasma through chemometric-assisted solid-phase extraction and liquid chromatography

Talanta ◽  
2018 ◽  
Vol 184 ◽  
pp. 173-183 ◽  
Author(s):  
Pedro Henrique Reis da Silva ◽  
Melina Luiza Vieira Diniz ◽  
Gerson Antônio Pianetti ◽  
Isabela da Costa César ◽  
Maria Elisa Scarpelli Ribeiro e Silva ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Human Plasma ◽  
Molecularly Imprinted Polymer ◽  
Solid Phase ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted
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