Low temperature additive manufacturing of three dimensional scaffolds for bone-tissue engineering applications: Processing related challenges and property assessment

2016 ◽  
Vol 103 ◽  
pp. 1-39 ◽  
Author(s):  
Alok Kumar ◽  
Sourav Mandal ◽  
Srimanta Barui ◽  
Ramakrishna Vasireddi ◽  
Uwe Gbureck ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
Low Temperature ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
Engineering Applications ◽  
Property Assessment

Fabrication of a chitosan/bioglass three-dimensional porous scaffold for bone tissue engineering applications

2014 ◽  
Vol 2 (38) ◽  
pp. 6611-6618 ◽  
Author(s):  
Jun Yang ◽  
Teng Long ◽  
Nan-Fei He ◽  
Ya-Ping Guo ◽  
Zhen-An Zhu ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Porous Scaffold ◽  
Three Dimensional ◽  
Bone Defects ◽  
Engineering Applications

A chitosan/bioglass three-dimensional porous scaffold with excellent biocompatibility and mechanical properties has been developed for the treatment of bone defects.

Preparation and characterization of a three-dimensional printed scaffold based on a functionalized polyester for bone tissue engineering applications

2011 ◽  
Vol 7 (5) ◽  
pp. 1999-2006 ◽  
Author(s):  
Hajar Seyednejad ◽  
Debby Gawlitta ◽  
Wouter J.A. Dhert ◽  
Cornelus F. van Nostrum ◽  
Tina Vermonden ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
Engineering Applications

Hybrid porous zirconia scaffolds fabricated using additive manufacturing for bone tissue engineering applications

2021 ◽  
Vol 123 ◽  
pp. 111950
Author(s):  
Kumaresan Sakthiabirami ◽  
Jin-Ho Kang ◽  
Jae-Gon Jang ◽  
Vaiyapuri Soundharrajan ◽  
Hyun-Pil Lim ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Engineering Applications ◽  
Porous Zirconia

scholarly journals Calcium Orthophosphate (CaPO4) Scaffolds for Bone Tissue Engineering Applications

2018 ◽  
Vol 1 (3) ◽  
pp. 25-93 ◽  
Author(s):  
Sergey V. Dorozhkin
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
Bone Grafts ◽  
Biologically Active ◽  
Growth Factor Delivery ◽  
Engineering Applications ◽  
Scaffold Materials

The chemical and structural similarities of calcium orthophosphates (abbreviated as CaPO4)to the mineral composition of natural bones and teeth have made them a good candidate for bone tissue engineering applications. Nowadays, a variety of natural or synthetic CaPO4-based biomaterials is produced and has been extensively used for dental and orthopedic applications. Despite their inherent brittleness, CaPO4 materials possess several appealing characteristics as scaffold materials. Namely, their biocompatibility and variable stoichiometry, thus surface charge density, functionality and dissolution properties, make them suitable for both drug and growth factor delivery. Therefore, CaPO4, especially hydroxyapatite (HA) and tricalcium phosphates (TCPs), have attracted a significant interest in simultaneous use as bone grafts and drug delivery vehicles. Namely, CaPO4-based three-dimensional (3D) scaffolds and/or carriers have been designed to induce bone formation and vascularization. These scaffolds are usually porous and harbor various types of drugs, biologically active molecules and/or cells. Over the past few decades, their application as bone grafts in combination with stem cells has gained much importance. This review discusses the source, manufacturing methods and advantages of using CaPO4 scaffolds for bone tissue engineering applications. Perspective future applications comprise drug delivery and tissue engineering purposes.

Towards Engineering Whole Bones via Endochondral Ossification

2013 ◽  
Author(s):  
Eamon J. Sheehy ◽  
Tatiana Vinardell ◽  
Conor T. Buckley ◽  
Daniel J. Kelly
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
Low Oxygen ◽  
Engineering Applications ◽  
Endochondral Bone ◽  
Oxygen Conditions

Tissue engineering applications aim to replace or regenerate damaged tissues through a combination of cells, three-dimensional scaffolds, and signaling molecules [1]. The endochondral approach to bone tissue engineering [2], which involves remodeling of an intermittent hypertrophic cartilaginous template, may be superior to the traditional intramembranous approach. Naturally derived hydrogels have been used extensively in tissue engineering applications [3]. Mesenchymal stem cell (MSC) seeded hydrogels may be a particularly powerful tool in scaling-up engineered endochondral bone grafts as the low oxygen conditions that develop within large constructs enhance in vitro chondrogenic differentiation and functional development [4]. A key requirement however, is that the hydrogel must allow for remodeling of the engineered hypertrophic cartilage into bone and also facilitate vascularization of the graft. The first objective of this study was to compare the capacity of different naturally derived hydrogels (alginate, chitosan, and fibrin) to generate in vivo endochondral bone. The secondary objective was to investigate the possibility of engineering a ‘scaled-up’ anatomically accurate distal phalange as a paradigm for whole bone tissue engineering.

scholarly journals Additive manufacturing of star poly(ε-caprolactone) wet-spun scaffolds for bone tissue engineering applications

2013 ◽  
Vol 28 (4) ◽  
pp. 320-340 ◽  
Author(s):  
Carlos Mota ◽  
Dario Puppi ◽  
Dinuccio Dinucci ◽  
Matteo Gazzarri ◽  
Federica Chiellini
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Engineering Applications

scholarly journals Porous zinc scaffolds for bone tissue engineering applications: A novel additive manufacturing and casting approach

2020 ◽  
Vol 110 ◽  
pp. 110738 ◽  
Author(s):  
Irsalan Cockerill ◽  
Yingchao Su ◽  
Subhasis Sinha ◽  
Yi-Xian Qin ◽  
Yufeng Zheng ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Engineering Applications
Sign in / Sign up

Export Citation Format

Share Document