Effects of manual therapy on fear avoidance, kinesiophobia and pain catastrophizing in individuals with chronic musculoskeletal pain: Systematic review and meta-analysis

2021 ◽  
Vol 51 ◽  
pp. 102311
Author(s):  
Danilo Harudy Kamonseki ◽  
Peter Christenson ◽  
S. Cyrus Rezvanifar ◽  
Letícia Bojikian Calixtre
Pain Medicine ◽  
2020 ◽  
Vol 21 (10) ◽  
pp. 2502-2517 ◽  
Author(s):  
Alberto Arribas-Romano ◽  
Josué Fernández-Carnero ◽  
Francisco Molina-Rueda ◽  
Santiago Angulo-Diaz-Parreño ◽  
Marcos José Navarro-Santana

Abstract Introduction Chronic musculoskeletal pain is a major health, social, and economic problem. Most of the subjects who suffer from chronic musculoskeletal pain present processes of central sensitization. Temporal summation and conditioned pain modulation are the two most commonly used clinical measures of this. The objective of this review is to evaluate the effects of physical therapy on temporal summation (TS) and conditioned pain modulation (CPM) in patients with chronic musculoskeletal pain. Methods This is a systematic review and meta-analysis. We searched the MEDLINE, EMBASE, CINAHL, EBSCO, PubMed, PEDro, Cochrane Collaboration Trials Register, Cochrane Database of Systematic Reviews, and SCOPUS databases. Different mesh terms and key words were combined for the search strategy, with the aim of encompassing all studies that have used any type of physical therapy treatment in patients with chronic musculoskeletal pain and have measured both TS and CPM. Results Eighteen studies remained for qualitative analysis and 16 for quantitative analysis. Statistically significant differences with a 95% confidence interval (CI) were obtained for TS (–0.21, 95% CI = –0.39 to –0.03, Z = 2.50, P = 0.02, N = 721) and CPM (0.34, 95% CI = 0.12 to 0.56, Z = 2.99, P = 0.003, N = 680) in favor of physical therapy as compared with control. Manual therapy produces a slight improvement in TS, and physical therapy modalities in general improve CPM. No significant differences between the subgroups of the meta-analysis were found. The methodological quality of the studies was high. Conclusions Physical therapy produces a slight improvement in central sensitization (CS)–related variables, with TS decreased and CPM increased when compared with a control group in patients with CMP. Only significant differences in TS were identified in the manual therapy subgroup.


2019 ◽  
Vol 20 (12) ◽  
pp. 1394-1415 ◽  
Author(s):  
Javier Martinez-Calderon ◽  
Mar Flores-Cortes ◽  
Jose Miguel Morales-Asencio ◽  
Alejandro Luque-Suarez

2004 ◽  
Vol 5 (1) ◽  
Author(s):  
Lorna Mason ◽  
R Andrew Moore ◽  
Jayne E Edwards ◽  
Sheena Derry ◽  
Henry J McQuay

Pain Medicine ◽  
2013 ◽  
Vol 14 (9) ◽  
pp. 1316-1331 ◽  
Author(s):  
Brendon Stubbs ◽  
Tarik T. Binnekade ◽  
Andy Soundy ◽  
Pat Schofield ◽  
Ivan P. J. Huijnen ◽  
...  

Toxins ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 640
Author(s):  
Simone Battista ◽  
Luca Buzzatti ◽  
Marialuisa Gandolfi ◽  
Cinzia Finocchi ◽  
Luca Falsiroli Maistrello ◽  
...  

Several studies have investigated the effect of botulinum toxin A (BoNT-A) for managing chronic musculoskeletal pain, bringing contrasting results to the forefront. Thus far, however, there has been no synthesis of evidence on the effect of BoNT-A as an adjunctive treatment within a multimodal approach. Hence, Medline via PubMed, EMBASE, and the Cochrane Library-CENTRAL were searched until November 2020 for randomised controlled trials (RCTs) that investigated the use of BoNT-A as an adjunctive therapy for chronic musculoskeletal pain. The risk of bias (RoB) and the overall quality of the studies were assessed through RoB 2.0 and the GRADE approach, respectively. Meta-analysis was conducted to analyse the pooled results of the six included RCTs. Four were at a low RoB, while two were at a high RoB. The meta-analysis showed that BoNT-A as an adjunctive therapy did not significantly decrease pain compared to the sole use of traditional treatment (SDM −0.89; 95% CI −1.91; 0.12; p = 0.08). Caution should be used when interpreting such results, since the studies displayed very high heterogeneity (I = 94%, p < 0.001). The overall certainty of the evidence was very low. The data retrieved from this systematic review do not support the use of BoNT-A as an adjunctive therapy in treating chronic musculoskeletal pain.


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