scholarly journals Mapping the intracellular metabolome of yeast biocapsules - Spherical structures of yeast attached to fungal pellets

2020 ◽  
Vol 58 ◽  
pp. 55-60
Author(s):  
Minami Ogawa ◽  
Teresa García-Martínez ◽  
Linda Bisson ◽  
Juan C. Mauricio ◽  
Juan Moreno ◽  
...  
Keyword(s):  
Fungal Pellets ◽  
Spherical Structures

Video real-time imaging of artificial membranes during freeze-drying by cryo-electron microscopy

1988 ◽  
Vol 46 ◽  
pp. 16-17
Author(s):  
Alan S. Rudolph ◽  
Ronald R. Price
Keyword(s):  
Real Time ◽  
Self Assembly ◽  
Freeze Drying ◽  
Video Capture ◽  
Drying Process ◽  
Artificial Membranes ◽  
The Past ◽  
Cryo Electron Microscopy ◽  
Spherical Structures ◽  
Capture Techniques

We have employed cryoelectron microscopy to visualize events that occur during the freeze-drying of artificial membranes by employing real time video capture techniques. Artificial membranes or liposomes which are spherical structures within internal aqueous space are stabilized by water which provides the driving force for spontaneous self-assembly of these structures. Previous assays of damage to these structures which are induced by freeze drying reveal that the two principal deleterious events that occur are 1) fusion of liposomes and 2) leakage of contents trapped within the liposome [1]. In the past the only way to access these events was to examine the liposomes following the dehydration event. This technique allows the event to be monitored in real time as the liposomes destabilize and as water is sublimed at cryo temperatures in the vacuum of the microscope. The method by which liposomes are compromised by freeze-drying are largely unknown. This technique has shown that cryo-protectants such as glycerol and carbohydrates are able to maintain liposomal structure throughout the drying process.

Nanoemulsions Loaded with Amphotericin B: Development, Characterization and Leishmanicidal Activity

2019 ◽  
Vol 25 (14) ◽  
pp. 1616-1622 ◽  
Author(s):  
Gabriela Muniz Félix Araújo ◽  
Gabriela Muniz Félix Araújo ◽  
Alana Rafaela Albuquerque Barros ◽  
Alana Rafaela Albuquerque Barros ◽  
João Augusto Oshiro-Junior ◽  
...  
Keyword(s):  
Amphotericin B ◽  
Average Diameter ◽  
Isopropyl Myristate ◽  
Neglected Diseases ◽  
Clinical Form ◽  
Hydrophobic Compounds ◽  
Internal Phase ◽  
Oil In Water ◽  
Spherical Structures ◽  
Lipid Formulations

Leishmaniasis is one of the most neglected diseases in the world. Its most severe clinical form, called visceral, if left untreated, can be fatal. Conventional therapy is based on the use of pentavalent antimonials and includes amphotericin B (AmB) as a second-choice drug. The micellar formulation of AmB, although effective, is associated with acute and chronic toxicity. Commercially-available lipid formulations emerged to overcome such drawbacks, but their high cost limits their widespread use. Drug delivery systems such as nanoemulsions (NE) have proven ability to solubilize hydrophobic compounds, improve absorption and bioavailability, increase efficacy and reduce toxicity of encapsulated drugs. NE become even more attractive because they are inexpensive and easy to prepare. The aim of this work was to incorporate AmB in NE prepared by sonicating a mixture of surfactants, Kolliphor® HS15 (KHS15) and Brij® 52, and an oil, isopropyl myristate. NE exhibited neutral pH, conductivity values consistent with oil in water systems, spherical structures with negative Zeta potential value, monomodal size distribution and average diameter of drug-containing droplets ranging from 33 to 132 nm. AmB did not modify the thermal behavior of the system, likely due to its dispersion in the internal phase. Statistically similar antileishmanial activity of AmB-loaded NE to that of AmB micellar formulation suggests further exploring them in terms of toxicity and effectiveness against amastigotes, with the aim of offering an alternative to treat visceral leishmaniasis.

Fungal pellets immobilized bacterial bioreactor for efficient nitrate removal at low C/N wastewater

2021 ◽  
pp. 125113
Author(s):  
Zhijie Zheng ◽  
Amjad Ali ◽  
Junfeng Su ◽  
Tinglin Huang ◽  
Yue Wang ◽  
...  
Keyword(s):  
Nitrate Removal ◽  
Fungal Pellets

Solid and Hollow Micro and Nano Spherical Structures: in Polysilicon and Phosphosilicate Glass

1994 ◽  
Vol 372 ◽  
Author(s):  
M. M. Farooqui ◽  
A. G. R. Evans
Keyword(s):  
Ion Beam ◽  
Three Dimensional ◽  
Optical Components ◽  
Circular Symmetry ◽  
Spherical Structures ◽  
Phosphosilicate Glass ◽  
Micro Systems ◽  
Micro Structures ◽  
Microfabrication Techniques

Fabrication of three dimensional micro structures in silicon and silicon related materials is becoming increasingly important for the realisation of micro systems comprising of sensors, actuators, transducers and analytical assemblies. Fabrication of such devices so far has been mostly in form of structures defined by the crystal planes of silicon, or has involved sophisticated technologies such as ion beam machining, replication using LIGA, or micromachining techniques involving a sequence of alignment and etch stages using binary masks. Structures with circular symmetry are of great interest as micro optical components amongst others, and these are not easily amenable to microfabrication techniques commonly employed.

A note on spherical structures in chars from vitrinites of coking rank

1977 ◽  
Vol 109 (1) ◽  
pp. 159-163 ◽  
Author(s):  
F. Goodarzi ◽  
D. G. Murchison
Keyword(s):  
Spherical Structures

Imaging of small spherical structures in CT: simulation study using measured point spread function

2007 ◽  
Vol 46 (3) ◽  
pp. 273-282 ◽  
Author(s):  
Masaki Ohkubo ◽  
Shinichi Wada ◽  
Masayuki Kunii ◽  
Toru Matsumoto ◽  
Kanae Nishizawa
Keyword(s):  
Simulation Study ◽  
Point Spread Function ◽  
Point Spread ◽  
Spread Function ◽  
Ct Simulation ◽  
Spherical Structures

Field Transforms for Multilayered Cylindrical and Spherical Structures of Finite Conductivity

1975 ◽  
Vol 53 (11) ◽  
pp. 1078-1087 ◽  
Author(s):  
E. Bahar
Keyword(s):  
Radius Of Curvature ◽  
Finite Conductivity ◽  
Electromagnetic Propagation ◽  
Wave Guides ◽  
Spherical Structures ◽  
Fourier Type ◽  
The Relationship ◽  
Conducting Cylinders ◽  
Dielectric Structures ◽  
Watson Transform

Problems of propagation around multilayered cylindrical or spherical structures possessing highly conducting cores have been analyzed in terms of discrete sets of modes. However, when propagation through the core of the structure is significant and of particular interest, the discrete set of modes is not suitable for the complete expansion of the electromagnetic fields.To provide a suitable basis for the expansion of the electromagnetic field in nonuniform multilayered, cylindrical or spheroidal, dielectric structures we derive expressions for the electric and magnetic field transforms consisting of both a discrete and a continuous spectrum of waves. The relationship between these transforms, the Kontorowich–Lebedev transform, and the discrete Watson transform is discussed. When the radius of curvature of the structure is infinite these transforms merge with generalized Fourier type transforms.The transforms can be used to investigate electromagnetic propagation through irregularly shaped dielectric wave guides, and through irregularly shaped spheroids. It can also be used to solve the problem of propagation in the interior (concave side) of irregularly shaped conducting cylinders or spheroids.

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