Stress-induced enhancement of fear learning: An animal model of posttraumatic stress disorder

2005 ◽  
Vol 29 (8) ◽  
pp. 1207-1223 ◽  
Author(s):  
Vinuta Rau ◽  
Joseph P. DeCola ◽  
Michael S. Fanselow
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Animal Model ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Fear Learning

A behavioral animal model of posttraumatic stress disorder featuring repeated exposure to situational reminders

1996 ◽  
Vol 39 (2) ◽  
pp. 129-134 ◽  
Author(s):  
Robert S. Pynoos ◽  
Ronald F. Ritzmann ◽  
Alan M. Steinberg ◽  
Armen Goenjian ◽  
Ioana Prisecaru
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Animal Model ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Repeated Exposure

scholarly journals Alterations in the hippocampal glycinergic system in an animal model of posttraumatic stress disorder

2010 ◽  
Vol 44 (15) ◽  
pp. 1069-1074 ◽  
Author(s):  
Shigeto Yamamoto ◽  
Shigeru Morinobu ◽  
Yasuyuki Iwamoto ◽  
Yuto Ueda ◽  
Shiro Takei ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Animal Model ◽  
Posttraumatic Stress ◽  
Stress Disorder

scholarly journals Amygdala Transcriptome and Cellular Mechanisms Underlying Stress-Enhanced Fear Learning in a Rat Model of Posttraumatic Stress Disorder

2010 ◽  
Vol 35 (6) ◽  
pp. 1402-1411 ◽  
Author(s):  
Igor Ponomarev ◽  
Vinuta Rau ◽  
Edmond I Eger ◽  
R Adron Harris ◽  
Michael S Fanselow
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Rat Model ◽  
Stress Disorder ◽  
Fear Learning ◽  
Cellular Mechanisms

Neurobiology of Trauma and Stressor-Related Disorders

2018 ◽  
Author(s):  
Marissa Elizabeth Maheu ◽  
Joseph Hunter Howie ◽  
Kerry James Ressler
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Stress Response ◽  
Posttraumatic Stress ◽  
Large Scale ◽  
Stress Disorder ◽  
Acute Stress ◽  
Molecular Techniques ◽  
Fear Learning ◽  
Recent Developments ◽  
Genomic Studies

Posttraumatic stress disorder (PTSD) and acute stress disorder are precipitated by exposure to one or more traumatic events, and result in debilitating fear-related symptoms. Advances made over the past several years have greatly improved our understanding of these disorders, as well as the neurobiological and genetic factors that contribute to their emergence and progression. In this review, we provide an overview of this research, with a particular focus on recent developments in understanding the neurocircuitry underlying relevant aspects of fear learning, including acquisition, generalization, and the extinction of fear. Molecular regulators of stress response and candidate genes implicated in PTSD are also discussed. Although there remains a great deal to learn about these disorders, novel approaches, large-scale genomic studies, and new molecular techniques promise to help untangle the neurobiology of trauma- and stressor-related illness over the coming years. This review contains 3 figures, 3 tables and 56 references Key words: Posttraumatic stress disorder, fear, genetics, GWAS, HPA stress response, neurocircuitry models of trauma, generalization, extinction learning.

The Role of the Galaninergic System in Modulating Stress-Related Responses in an Animal Model of Posttraumatic Stress Disorder

2009 ◽  
Vol 65 (5) ◽  
pp. 383-391 ◽  
Author(s):  
Nitsan Kozlovsky ◽  
Michael A. Matar ◽  
Zeev Kaplan ◽  
Joseph Zohar ◽  
Hagit Cohen
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Animal Model ◽  
Posttraumatic Stress ◽  
Stress Disorder
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