Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations

2003 ◽  
Vol 352 (3) ◽  
pp. 216-220 ◽  
Author(s):  
Yan Jiang ◽  
Weilin Yang ◽  
Yuqing Zhou ◽  
Lan Ma
Keyword(s):  
Gene Expression ◽  
Rat Brain ◽  
Mdm2 Gene ◽  
Double Minute ◽  
Murine Double Minute

scholarly journals Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene

BMC Cancer ◽  
2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Kirstin Mittelstrass ◽  
Wiebke Sauter ◽  
Albert Rosenberger ◽  
Thomas Illig ◽  
Maria Timofeeva ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cigarette Smoking ◽  
Early Onset ◽  
Mdm2 Gene ◽  
Double Minute ◽  
Murine Double Minute

scholarly journals Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene

ISRN Urology ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Taku Naiki ◽  
Shuzo Hamamoto ◽  
Noriyasu Kawai ◽  
Aya Naiki-Ito ◽  
Yoshiyuki Kojima ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Therapeutic Strategy ◽  
Dedifferentiated Liposarcoma ◽  
Fish Analysis ◽  
Mdm2 Gene ◽  
Double Minute ◽  
Murine Double Minute

Surgical resection was performed on a 47-year-old woman for a retroperitoneal mass that weighed 8.5 kg. Histological examination revealed a myxoid sarcomatous tumor. Because diagnosis could not be determined by immunohistochemistry, attention was focused on MDM2 (murine double minute) gene amplification by fluorescence in situ hybridization (FISH) analysis. The tumor was finally determined to be a dedifferentiated liposarcoma. We experienced a case of a giant retroperitoneal dedifferentiated liposarcoma. FISH analysis was useful for the diagnosis and determination of the therapeutic strategy.

scholarly journals Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility

2015 ◽  
Vol 23 (3) ◽  
pp. 521-530 ◽  
Author(s):  
S Fouchécourt ◽  
G Livera ◽  
S Messiaen ◽  
B Fumel ◽  
A-S Parent ◽  
...  
Keyword(s):  
Male Sterility ◽  
Sertoli Cells ◽  
Mdm2 Gene ◽  
Double Minute ◽  
Murine Double Minute
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