Traffic of leukocytes in the central nervous system is associated with chemokine up-regulation in a severe model of herpes simplex encephalitis: An intravital microscopy study

2008 ◽  
Vol 445 (1) ◽  
pp. 18-22 ◽  
Author(s):  
Márcia Carvalho Vilela ◽  
Daniel Santos Mansur ◽  
Norinne Lacerda-Queiroz ◽  
David Henrique Rodrigues ◽  
Rosa Maria Esteves Arantes ◽  
...  
Author(s):  
Tamara Kaplan ◽  
Tracey Milligan

The video in this chapter discusses infections of the central nervous system (CNS), meningitis including its symptoms (fever, headache, nuchal rigidity, altered level of consciousness), its causes (bacterial, fungal, viral, or aseptic), and how the CSF profile provides clues to the etiology. The chapter also discusses encephalitis, its symptoms (seizures, other focal neurologic symptoms). Patients with Herpes Simplex Encephalitis may show T2 hyperintensities in the anterior temporal lobes and limbic structures on MRI. CSF may show xanthochromia and positive PCR for HSV1 or HSV2.


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