scholarly journals Pharmacologic MRI (phMRI) as a tool to differentiate Parkinson's disease–related from age-related changes in basal ganglia function

2015 ◽  
Vol 36 (2) ◽  
pp. 1174-1182 ◽  
Author(s):  
Anders H. Andersen ◽  
Peter A. Hardy ◽  
Eric Forman ◽  
Greg A. Gerhardt ◽  
Don M. Gash ◽  
...  
Author(s):  
A.H. Rajput ◽  
B. Rozdilsky ◽  
L. Ang ◽  
Alex Rajput

ABSTRACT:Parkinsonian features, notably resting tremor may be seen in some essential tremor patients but the significance of those is unknown. The reported risk of parkinsonism in essential tremor patients varies from being unchanged to 35 times higher than expected. We studied 9 patients with essential tremor who had autopsies. In 6 of the 9 (66%) resting tremor was noted and in 3 (33%) cases fully developed parkinsonism was noted. The parkinsonism was consequent to neuroleptic usage in 2 and to basal ganglia status lacunaris and cribrosus in one case but no consistent abnormalities were noted in 3 essential tremor only and 3 essential tremor plus resting tremor cases. We conclude that resting tremor is an age-related natural evolution in some essential tremor patients. We recommend that the additional diagnosis of parkinsonism in the essential tremor be made only when resting tremor, bradykinesia and rigidity are all evident. The risk of ideopathic Parkinson's disease in essential tremor cases is similar to the general population.


2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Tultul Nayyar ◽  
Michael Bubser ◽  
Marcus C Ferguson ◽  
Ariel Y Deutch ◽  
Twum A Ansah

2014 ◽  
Vol 26 (5) ◽  
pp. 505-510 ◽  
Author(s):  
Monika Zawadka-Kunikowska ◽  
Paweł Zalewski ◽  
Jacek J. Klawe ◽  
Joanna Pawlak ◽  
Małgorzata Tafil-Klawe ◽  
...  

Author(s):  
Kazumasa Shindo ◽  
Yuto Morishima ◽  
Yumi Suwa ◽  
Toko Fukao ◽  
Takafumi Kurita ◽  
...  

2011 ◽  
Vol 37 (2) ◽  
pp. 161-167 ◽  
Author(s):  
A. S. Litvinova ◽  
P. O. Ratmanova ◽  
E. I. Evina ◽  
R. R. Bogdanov ◽  
A. N. Kunitsyna ◽  
...  

1989 ◽  
Vol 28 (03) ◽  
pp. 92-94 ◽  
Author(s):  
C. Neumann ◽  
H. Baas ◽  
R. Hefner ◽  
G. Hör

The symptoms of Parkinson’s disease often begin on one side of the body and continue to do so as the disease progresses. First SPECT results in 4 patients with hemiparkinsonism using 99mTc-HMPAO as perfusion marker are reported. Three patients exhibited reduced tracer uptake in the contralateral basal ganglia One patient who was under therapy for 1 year, showed a different perfusion pattern with reduced uptake in both basal ganglia. These results might indicate reduced perfusion secondary to reduced striatal neuronal activity.


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