Frontotemporal oxyhemoglobin dynamics predict performance accuracy of dance simulation gameplay: Temporal characteristics of top-down and bottom-up cortical activities

NeuroImage ◽  
2014 ◽  
Vol 85 ◽  
pp. 461-470 ◽  
Author(s):  
Yumie Ono ◽  
Yasunori Nomoto ◽  
Shohei Tanaka ◽  
Keisuke Sato ◽  
Sotaro Shimada ◽  
...  
2020 ◽  
Author(s):  
Fuyin Yang ◽  
Hao Zhu ◽  
Lingfang Yu ◽  
Weihong Lu ◽  
Chen Zhang ◽  
...  

AbstractsAuditory verbal hallucinations (AVHs) are one of the most pronounced symptoms that manifest the underlying mechanisms of deficits in schizophrenia. Cognitive models postulate that malfunctioned source monitoring incorrectly weights the top-down prediction and bottom-up sensory processing and causes hallucinations. Here, we investigate the featural-temporal characteristics of source monitoring in AVHs. Schizophrenia patients with and without AVHs, and healthy controls identified target tones in noise at the end of tone sequences. Predictions of different timescales were manipulated by either an alternating pattern in the preceding tone sequences, or a repetition between the target tone and the tone immediately before. The sensitivity index, d’, was obtained to assess the modulation of predictions on tone identification. We found that patients with AVHs showed higher d’ when the target tones conformed to the long-term regularity of alternating pattern in the preceding tone sequence than that when the targets were inconsistent with the pattern. Whereas, the short-term regularity of repetitions modulated the tone identification in patients without AVHs. Predictions did not influence tone identification in healthy controls. These findings suggest that malfunctioned source monitoring in AVHs heavily weights predictions to form incorrect perception. The weighting function in source monitoring can extend to the process of basic tonal features, and predictions at multiple timescales differentially modulate perception in different clinical populations. These collaboratively reveal the featural and temporal characteristics of weighting function in source monitoring of AVHs and suggest that the malfunctioned interaction between top-down and bottom-up processes might underlie the development of auditory hallucinations.HighlightsMalfunctioned source monitoring incorrectly weights the top-down prediction and bottom-up sensory processing underlie pathogenesis of auditory verbal hallucinations in schizophrenia.The weighting function in top-down predictions and bottom-up sensory processing can extend to tonal features.Predictions at multiple timescales differentially modulate perception in different clinical schizophrenia populations.


PsycCRITIQUES ◽  
2005 ◽  
Vol 50 (19) ◽  
Author(s):  
Michael Cole
Keyword(s):  
Top Down ◽  

Author(s):  
Sadari Sadari ◽  
Nurhidayat Nurhidayat ◽  
Rafiqah Rafiqah
Keyword(s):  
Top Down ◽  

Humanisme religius telah mengantarkan pada era kesadaran bahwa peradaban manusia harus memiliki dua arus yang saling menunjang. Selama ini arus balik dalam bidang ekonomi hanya menonjolkan arus balik vertikal atas kebawah (model top down) yang didominasi oleh sistem ekonomi kapitalis dan sosialis, sedangkan di sisi lain mengesampingkan arus balik vertikal dari bawah ke atas (model bottom up) yang didominasi oleh sistem ekonomi syariah, sehingga dampaknya adalah adanya kesenjangan ekonomi yang sangat tajam. Paper ini mewujudkan peran penting, yakni menghubungkan dua arus tersebut secara timbal-balik, yakni mempertemukan arus pertama dengan arus balik kedua, sehingga akan menghasilkan dampak yang positif, progresif, kreatif dan produktif, kemudian pada akhirnya akan dapat meng-optomal-kan ekonomi syariah untuk menciptakan goodgovernance, post goodgovernance secara berkelanjutan, tentunya dengan bantuan peran media kontemporer yang kian update. Ekonomi syariah juga merupakan pilar dan nilai dasar, dari sikap keyakinan dan sikap rasionalitas untuk sanggup menciptakan terwujudnya pemberdayaan dan kesejahteraan sekaligus pengentasan kemiskinan dalam masyarakat di Indonesia.


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