Auditory inhibitory gating in medial prefrontal cortex: Single unit and local field potential analysis

Neuroscience ◽  
2006 ◽  
Vol 141 (1) ◽  
pp. 47-65 ◽  
Author(s):  
R.P. Mears ◽  
A.C. Klein ◽  
H.C. Cromwell
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Local Field ◽  
Local Field Potential ◽  
Single Unit ◽  
Field Potential ◽  
Potential Analysis

scholarly journals Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations

2018 ◽  
Vol 14 ◽  
pp. 174480691878568 ◽  
Author(s):  
Bo Fu ◽  
Shao-nan Wen ◽  
Bin Wang ◽  
Kun Wang ◽  
Ji-yan Zhang ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Local Field ◽  
Local Field Potential ◽  
Field Potential ◽  
Neural Oscillations

Reduced local field potential power in the medial prefrontal cortex by noxious stimuli

2016 ◽  
Vol 127 ◽  
pp. 92-99 ◽  
Author(s):  
Ai-Ling Li ◽  
Xiaofei Yang ◽  
Jung-Chih Chiao ◽  
Yuan Bo Peng
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Local Field ◽  
Local Field Potential ◽  
Field Potential ◽  
Noxious Stimuli

scholarly journals Aberrant Auditory Steady-State Response of Awake Mice After Single Application of the NMDA Receptor Antagonist MK-801 Into the Medial Geniculate Body

2020 ◽  
Vol 23 (7) ◽  
pp. 459-468 ◽  
Author(s):  
Xuejiao Wang ◽  
Yingzhuo Li ◽  
Jingyu Chen ◽  
Zijie Li ◽  
Jinhong Li ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Steady State ◽  
Local Field ◽  
Local Field Potential ◽  
Phase Locking ◽  
Field Potential ◽  
Medial Geniculate Body ◽  
Systemic Administration ◽  
Mk 801 ◽  
Medial Geniculate

Abstract Background Systemic administration of noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonists such as MK-801 is widely used to model psychosis of schizophrenia (SZ). Acute systemic MK-801 in rodents caused an increase of the auditory steady-state responses (ASSRs), the oscillatory neural responses to periodic auditory stimulation, while most studies in patients with SZ reported a decrease of ASSRs. This inconsistency may be attributable to the comprehensive effects of systemic administration of MK-801. Here, we examined how the ASSR is affected by selectively blocking NMDAR in the thalamus. Methods We implanted multiple electrodes in the auditory cortex (AC) and prefrontal cortex to simultaneously record the local field potential and spike activity (SA) of multiple sites from awake mice. Click-trains at a 40-Hz repetition rate were used to evoke the ASSR. We compared the mean trial power and phase-locking factor and the firing rate of SA before and after microinjection of MK-801 (1.5 µg) into the medial geniculate body (MGB). Results We found that both the AC and prefrontal cortex showed a transient local field potential response at the onset of click-train stimulus, which was less affected by the application of MK-801 in the MGB. Following the onset response, the AC also showed a response continuing throughout the stimulus period, corresponding to the ASSR, which was suppressed by the application of MK-801. Conclusion Our data suggest that the MGB is one of the generators of ASSR, and NMDAR hypofunction in the thalamocortical projection may account for the ASSR deficits in SZ.

A study on combining local field potential and single unit activity for better neural decoding

2011 ◽  
Vol 21 (2) ◽  
pp. 165-172 ◽  
Author(s):  
Shaomin Zhang ◽  
Bo Jiang ◽  
Junming Zhu ◽  
Qiaosheng Zhang ◽  
Weidong Chen ◽  
...  
Keyword(s):  
Local Field ◽  
Unit Activity ◽  
Local Field Potential ◽  
Single Unit ◽  
Field Potential ◽  
Single Unit Activity ◽  
Neural Decoding

scholarly journals Effect of propofol on local field potential in rat prefrontal cortex during working memory task

2012 ◽  
Vol 02 (03) ◽  
pp. 166-171
Author(s):  
Xinyu Xu ◽  
Guolin Wang ◽  
Wenqian Zhai ◽  
Wenwen Bai ◽  
Tiaotiao Liu ◽  
...  
Keyword(s):  
Working Memory ◽  
Prefrontal Cortex ◽  
Local Field ◽  
Local Field Potential ◽  
Memory Task ◽  
Field Potential
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