scholarly journals A randomized, placebo-controlled trial of the benzoquinone idebenone in a mouse model of OPA1-related dominant optic atrophy reveals a limited therapeutic effect on retinal ganglion cell dendropathy and visual function

Neuroscience ◽  
2016 ◽  
Vol 319 ◽  
pp. 92-106 ◽  
Author(s):  
T.G. Smith ◽  
S. Seto ◽  
P. Ganne ◽  
M. Votruba
Keyword(s):  
Mouse Model ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Therapeutic Effect ◽  
Optic Atrophy ◽  
Visual Function ◽  
Controlled Trial ◽  
Retinal Ganglion ◽  
Dominant Optic Atrophy

scholarly journals OPA1 gene therapy prevents retinal ganglion cell loss in a Dominant Optic Atrophy mouse model

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Emmanuelle Sarzi ◽  
Marie Seveno ◽  
Camille Piro-Mégy ◽  
Lucie Elzière ◽  
Mélanie Quilès ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Mouse Model ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Atrophy ◽  
Cell Loss ◽  
Retinal Ganglion ◽  
Dominant Optic Atrophy ◽  
Opa1 Gene

Early Macular Retinal Ganglion Cell Loss in Dominant Optic Atrophy: Genotype-Phenotype Correlation

2014 ◽  
Vol 158 (3) ◽  
pp. 628-636.e3 ◽  
Author(s):  
Piero Barboni ◽  
Giacomo Savini ◽  
Maria Lucia Cascavilla ◽  
Leonardo Caporali ◽  
Jacopo Milesi ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Atrophy ◽  
Cell Loss ◽  
Retinal Ganglion ◽  
Phenotype Correlation ◽  
Dominant Optic Atrophy ◽  
Genotype Phenotype Correlation

scholarly journals Pattern of retinal ganglion cell loss in dominant optic atrophy due to OPA1 mutations

Eye ◽  
2011 ◽  
Vol 25 (5) ◽  
pp. 596-602 ◽  
Author(s):  
P Yu-Wai-Man ◽  
M Bailie ◽  
A Atawan ◽  
P F Chinnery ◽  
P G Griffiths
Keyword(s):  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Atrophy ◽  
Cell Loss ◽  
Retinal Ganglion ◽  
Dominant Optic Atrophy

XIAP gene therapy effects on retinal ganglion cell structure and function in a mouse model of glaucoma

Gene Therapy ◽  
2021 ◽  
Author(s):  
Shagana Visuvanathan ◽  
Adam N. Baker ◽  
Pamela S. Lagali ◽  
Stuart G. Coupland ◽  
Garfield Miller ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Mouse Model ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Structure ◽  
Structure And Function ◽  
Retinal Ganglion ◽  
And Function
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