Determination of distal dose edge location by measuring right-angled prompt-gamma rays from a 38MeV proton beam

Author(s):  
C.H. Min ◽  
J.W. Kim ◽  
M.Y. Youn ◽  
C.H. Kim
1976 ◽  
Vol 32 (1) ◽  
pp. 105-116 ◽  
Author(s):  
I. S. Giles ◽  
M. Peisach
Keyword(s):  

2013 ◽  
Vol 58 (17) ◽  
pp. 5821-5831 ◽  
Author(s):  
Jerimy C Polf ◽  
Rajesh Panthi ◽  
Dennis S Mackin ◽  
Matt McCleskey ◽  
Antti Saastamoinen ◽  
...  

2018 ◽  
Vol 14 (4) ◽  
Author(s):  
James Della-Giustina ◽  
Johnlemuel Casilag ◽  
Elizabeth Gregorio ◽  
Aniebiet Jacobs

Proton beam radiation treatment was first proposed by Robert Wilson in 1946. The advantage of proton beam radiation is that the lethal dose of radiation is delivered by a sharp increase toward the end of the beam range. This sharp increase, known as the Bragg peak, allows for the possibility of reducing the exposure of healthy tissue to radiation when comparing to x-ray radiation treatment. As the proton beam interacts with the molecules in the body, gamma rays are emitted. The origin of the gamma rays gives the location of the proton beam in the body, therefore, gamma ray imaging allows physicians to better take advantage of the benefits of proton beam radiation. These gamma rays are detected using a Compton Camera (CC) while the SOE algorithm is used to reconstruct images of these gamma rays as they are emitted from the patient. This imaging occurs while the radiation dose is delivered, which would allow the physician to make adjustments in real time in the treatment room, provided the image reconstruction is computed fast enough. This project focuses on speeding up the image reconstruction software with the use of parallel computing techniques involving MPI. Additionally, we demonstrate the use of the VTune performance analyzer to identify bottlenecks in a parallel code. KEYWORDS: Proton Beam Therapy; Image Reconstruction; SOE Algorithm; Parallel Computing; High Performance Computing; Medical Imaging; Prompt Gamma Imaging; Radiotherapy


2004 ◽  
Vol 813 ◽  
Author(s):  
Rick L. Paul

ABSTRACTAn instrument for prompt gamma-ray activation analysis (PGAA) at the NIST Center for Neutron Research has proven useful for the measurement of hydrogen and other elements in a variety of materials. The sample is irradiated by a beam of low energy neutrons. Gamma-rays emitted by atomic nuclei upon neutron capture are measured and elemental concentrations determined by comparison with appropriate standards. The detection limit for hydrogen is < 5 mg/kg in most materials, and 2 mg/kg for hydrogen measured in silicon. The instrument has been used to measure hydrogen mass fractions of < 100 mg/kg in high purity germanium, and < 10 mg/kg in quartz. More recently PGAA has been used to measure hydrogen in 1 μm thick porous thin films on a silicon substrate, and in crystals of silicon carbide and cerium aluminate.


2011 ◽  
Vol 56 (10) ◽  
pp. 3047-3059 ◽  
Author(s):  
Daniel Robertson ◽  
Jerimy C Polf ◽  
Steve W Peterson ◽  
Michael T Gillin ◽  
Sam Beddar

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Costanza M. V. Panaino ◽  
Ranald I. Mackay ◽  
Karen J. Kirkby ◽  
Michael J. Taylor

AbstractA new technique for range verification in proton beam therapy has been developed. It is based on the detection of the prompt γ rays that are emitted naturally during the delivery of the treatment. A spectrometer comprising 16 LaBr3(Ce) detectors in a symmetrical configuration is employed to record the prompt γ rays emitted along the proton path. An algorithm has been developed that takes as inputs the LaBr3(Ce) detector signals and reconstructs the maximum γ-ray intensity peak position, in full 3 dimensions. For a spectrometer radius of 8 cm, which could accommodate a paediatric head and neck case, the prompt γ-ray origin can be determined from the width of the detected peak with a σ of 4.17 mm for a 180 MeV proton beam impinging a water phantom. For spectrometer radii of 15 and 25 cm to accommodate larger volumes this value increases to 5.65 and 6.36 mm. For a 8 cm radius, with a 5 and 10 mm undershoot, the σ is 4.31 and 5.47 mm. These uncertainties are comparable to the range uncertainties incorporated in treatment planning. This work represents the first step towards a new accurate, real-time, 3D range verification device for spot-scanning proton beam therapy.


2016 ◽  
Vol 25 (4) ◽  
pp. 367
Author(s):  
Tran Tuan Anh ◽  
Pham Ngoc Son ◽  
Vuong Huu Tan

The relative intensities of prompt g-rays from the 35Cl(n, g)36Cl reation with thermal neutron have been used as secondary g-ray intensity standards for the prompt gamma neutron activation analysis (PGNAA) and for nuclear data measurements due to a high capture cross section. The filter neutron technique was applied for producing a thermal neutron beam at the neutron channel No. 4 of the Dalat nuclear research reactor. The neutron flux and Cd-ratio are 8.72 ´ 106 n.cm-2.s-1and 134, respectively, determined by the gold foil activation method. A new PGNAA system with a HPGe detector of 58% relative efficiency and a digital spectrometer was used to detect prompt gamma rays from the 35Cl(n, g)36Cl reaction. In this work, relative intensities of 23 prompt g-rays have been determined on the filtered thermal neutron beam. The present results within accuracy 3.0% or better are in good agreement with literature values and data from previous measurements.


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