Development and validation of a gamma-ray detection response model for neutron-diagnosed subcritical experiments

2021 ◽  
Vol 1014 ◽  
pp. 165755
Author(s):  
Andrew L. Cooper ◽  
J. Winkelbauer ◽  
P. Koehler ◽  
G. Rusev ◽  
R. Olson ◽  
...  
Keyword(s):  
Gamma Ray ◽  
Response Model ◽  
Detection Response ◽  
Development And Validation

scholarly journals Development and validation of a gas chromatography method for the determination of β-caryophyllene in clove extract and its application

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mi Hee Park ◽  
Chul Jin Kim ◽  
Jin Young Lee ◽  
In Seon Kim ◽  
Sung-Kyu Kim
Keyword(s):  
Active Constituent ◽  
Chromatography Method ◽  
Ich Guidelines ◽  
Specificity Test ◽  
Detection Response ◽  
Standard Solution ◽  
Clove Extract ◽  
Pharmaceutical Uses ◽  
Development And Validation

AbstractThe purpose of this study is to check the effectiveness of the analysis method that separates and quantifies β-caryophyllene among clove extracts and validate according to current ICH guidelines. The β-caryophyllene was active constituent of clove buds. The developed method gave a good detection response. In the specificity test, the standard solution was detected at about 17.32 min, and the test solution was detected at 17.32 min. The linearity of β-caryophyllen was confirmed, and at this time, the correlation coefficient (R2) of the calibration curve showed a high linearity of 0.999 or more in the concentration range. The levels of LOD and LOQ were 1.28 ug/mL and 3.89 ug/mL, respectively. The accuracy was confirmed to be 101.6–102.2% and RSD 0.95 ~ 1.31%. As a result of checking the repeatability and inter-tester reproducibility to confirm the precision, the RSD was found to be 1.34 ~ 2.69%. This validated GC method was successfully applied to a soft capsule containing clove extract and other materials for clinical trials. Therefore, this method can be used as an analytical tool for quality control of various samples, including clove extracts and their products of food and pharmaceutical uses.

MEDLI2 Material Response Model Development and Validation

2022 ◽  
Author(s):  
Joshua Monk ◽  
Jay D. Feldman ◽  
Milad Mahzari ◽  
Jose A. Santos ◽  
Todd R. White ◽  
...  
Keyword(s):  
Model Development ◽  
Response Model ◽  
Material Response ◽  
Development And Validation

scholarly journals Tactics of political lying: The Iguanas affair

2015 ◽  
Vol 13 (4) ◽  
pp. 837-856
Keyword(s):  
Deception Detection ◽  
The Other ◽  
Management Model ◽  
Background Information ◽  
Response Model ◽  
Media Audiences ◽  
Key Players ◽  
The Media ◽  
Detection Response

Political lying recurrently becomes a major issue in the media. Audience members seldom have first-hand information and hence rely on media stories to assess claims. Although background information may not be available, the tactics used by key players are more likely to be reported. Two models for analysing tactics are introduced, one based on methods of deception, detection and response, the other based on methods to reduce or increase outrage over something perceived to be wrong. Each model is applied to claims and counter-claims concerning the behaviour of two Australian politicians. Most of the tactics used in the case study fit the deception-detection-response model, but some do not; the outrage management model overcomes these limitations: nearly all tactics used fit into the model’s categories. Media audiences, by being aware of likely tactics, can better judge whether lying is involved. Keywords: lying; deception; politicians; detection; tactics; outrage

scholarly journals Development and Validation of Overpressure Response Model in Steel Tunnels Subjected to External Explosion

2020 ◽  
Vol 10 (18) ◽  
pp. 6166 ◽  
Author(s):  
Cheng-Wei Hung ◽  
Hsin-hung Lai ◽  
Bor-Cherng Shen ◽  
Pin-Wen Wu ◽  
Tai-An Chen
Keyword(s):  
Finite Element ◽  
Numerical Results ◽  
Experimental Results ◽  
Response Model ◽  
Finite Element Code ◽  
Scaled Distance ◽  
Development And Validation

This study employed C4 explosives to evaluate the overpressure response in steel tunnels subjected to external explosions. The explosive scaled distance of the C4 charge from 2.15 to 3.26 m/kg1/3 was evaluated by experiments and the hydrodynamic finite element code LS-DYNA. The numerical results are in agreement with the experimental results. A simple way to estimate the overpressure in steel tunnels was proposed in this paper. The proposed methodology is both useful and efficient and can be further developed for designing protection for military structures and other facilities against explosion.

scholarly journals Development and validation of a gas chromatography method for the determination of β -caryophyllene in clove extract and its application

2021 ◽  
Author(s):  
Mi Hee Park ◽  
Chul Jin Kim ◽  
Jin Young Lee ◽  
In Seon Kim ◽  
Sung-kyu Kim
Keyword(s):  
Active Constituent ◽  
Chromatography Method ◽  
Ich Guidelines ◽  
Specificity Test ◽  
Detection Response ◽  
Standard Solution ◽  
Clove Extract ◽  
Pharmaceutical Uses ◽  
Development And Validation

Abstract The purpose of this study is to check the effectiveness of the analysis method that separates and quantifies β-caryophyllene among clove extracts and validate according to current ICH guidelines. The beta caryophyllene was active constituent of clove buds. The developed method gave a good detection response. In the specificity test, the standard solution was detected at about 17.316 minutes, and the test solution was detected at 17.317 minutes. The linearity of β-caryophyllen was confirmed, and at this time, the correlation coefficient (R 2 ) of the calibration curve showed a high linearity of 0.999 or more in the concentration range. The levels of LOD and LOQ were 1.28 ug/mL and 3.89 ug/mL, respectively. The accuracy was confirmed to be 101.6 ~ 102.2% and RSD 0.95 ~ 1.31%. As a result of checking the repeatability and inter-tester reproducibility to confirm the precision, the RSD was found to be 1.34 ~ 2.69%. This validated GC method was successfully applied to a soft capsule containing clove extract and other materials for clinical trials. Therefore, this method can be used as an analytical tool for quality control of various samples including clove extracts and their products for food and pharmaceutical uses.

Tactics of political lying

2014 ◽  
Vol 13 (4) ◽  
pp. 837-856 ◽  
Author(s):  
Brian Martin
Keyword(s):  
Deception Detection ◽  
Management Model ◽  
Background Information ◽  
Response Model ◽  
Content Type ◽  
Media Audiences ◽  
Key Players ◽  
The Media ◽  
Detection Response

Political lying recurrently becomes a major issue in the media. Audience members seldom have first-hand information and hence rely on media stories to assess claims. Although background information may not be available, the tactics used by key players are more likely to be reported. Two models for analysing tactics are introduced, one based on methods of deception, detection and response, the other based on methods to reduce or increase outrage over something perceived to be wrong. Each model is applied to claims and counter-claims concerning the behaviour of two Australian politicians. Most of the tactics used in the case study fit the deception-detection-response model, but some do not; the outrage management model overcomes these limitations: nearly all tactics used fit into the model’s categories. Media audiences, by being aware of likely tactics, can better judge whether lying is involved.

scholarly journals Development and Validation of a Dynamic Response Model for a Cold Flow Circulating Fluidized Bed

2016 ◽  
Vol 56 (1) ◽  
pp. 288-300 ◽  
Author(s):  
Esmail R. Monazam ◽  
Ronald W. Breault ◽  
Adam D. Freed ◽  
Lawrence Shadle ◽  
Larry O. Lawson ◽  
...  
Keyword(s):  
Dynamic Response ◽  
Fluidized Bed ◽  
Circulating Fluidized Bed ◽  
Response Model ◽  
Cold Flow ◽  
Development And Validation
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