Adult-onset Satoyoshi syndrome in a young male

Adult onset Still’s disease (AOSD) is a rare inammatory disease characterized by fever, arthralgia, rash, sore throat, lymphadenopathy, hepatomegaly and/or splenomegaly. It is a rare cause of pyrexia of unknown origin (PUO) and should be considered once the more common infectious, rheumatological and malignant causes have been excluded. This is usually a diagnosis of exclusion. Yamaguchi criteria can be used for diagnosis. Patients of AOSD show an excellent response to Non-steroidal anti-inammatory drugs (NSAIDs), however some may not have a sustained effect, in which case glucocorticoids have to be considered. Here’s a case of a young male patient who was evaluated for the cause of pyrexia of unknown origin.

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A young male with walking difficulties and subacute brainstem dysfunction: Adult-onset Leigh syndrome

Journal of the Neurological Sciences ◽

10.1016/j.jns.2021.119363 ◽

2021 ◽

Vol 429 ◽

pp. 119363

Author(s):

Elia Cipriano ◽

Domizia Vecchio ◽

Letizia Mazzini ◽

Gionata Strigaro ◽

Roberto Cantello ◽

...

Keyword(s):

Young Male ◽

Leigh Syndrome ◽

Adult Onset ◽

Brainstem Dysfunction

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CASE REPORT: REMISSION OF THE ADULT ONSET STILL DISEASE, IN A YOUNG MALE PATIENT TREATED WITH ETANERCEPT

JCR Journal of Clinical Rheumatology ◽

10.1097/01.rhu.0000226785.34598.cb ◽

2006 ◽

Vol 12 (Supplement) ◽

pp. S14 ◽

Cited By ~ 1

Author(s):

E Puertas ◽

J Rondon ◽

C C. Rondon

Keyword(s):

Case Report ◽

Male Patient ◽

Young Male ◽

Adult Onset ◽

Still Disease

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Ultrastructural Study of Human Testicular Biopsies in Infertility

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100090762 ◽

1976 ◽

Vol 34 ◽

pp. 156-157

Author(s):

Shirley Siew ◽

Philip Troen ◽

Howard R. Nankin

Keyword(s):

Electron Microscopy ◽

Transmission Electron Microscopy ◽

Basement Membrane ◽

Leydig Cells ◽

Clinical Evidence ◽

Young Male ◽

Germinal Epithelium ◽

Transmission Electron ◽

Age Range ◽

Male Subjects

Testicular biopsies were obtained from six young male subjects (age range 24-33) who complained of infertility and who had clinical evidence of oligospermia. This was confirmed on histological examination which showed a broad spectrum from profound hypospermatogenesis to relatively normal appearing germinal epithelium. Thickening of the tubular walls was noted in half of the cases and slight peritubular fibrosis in one. The Leydig cells were reported as normal or unremarkable.Transmission electron microscopy showed that the thickening of the supporting tissue of the germinal epithelium was caused more by an increase in the thickness of the layers of the lamina propria than of the tubular wall itself. The changes in the basement membrane of the tubular wall consisted mostly of a greater degree of infolding into the tubule and some reduplication which gave rise to a multilayered appearance.

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Remission of Recurrent Cochlear Hydrops Associated With Bromocriptine Treatment for Macroprolactinoma

American Journal of Audiology ◽

10.1044/2019_aja-18-0191 ◽

2019 ◽

Vol 28 (3) ◽

pp. 548-552

Author(s):

Andro Košec ◽

Ivan Kruljac ◽

Jakov Ajduk

Keyword(s):

Dopamine Receptors ◽

Male Patient ◽

Endolymphatic Hydrops ◽

Young Male ◽

Oral Steroid ◽

Case Description ◽

Diuretic Treatment ◽

Potential Therapeutic Role ◽

Transient Improvement ◽

Systemic Glucocorticoids

Objective Current recommendations for cochlear hydrops treatment include systemic glucocorticoids and diuretics. Cochlear cells express dopamine receptors, although their role is unknown in the pathophysiology of cochlear hydrops. Case Description We report the case of remission of recurrent right-sided cochlear hydrops in a young male patient treated with bromocriptine due to pituitary macroprolactinoma. Transient improvement was observed after oral steroid and diuretic treatment, but cochlear hydrops recurred until the dose of bromocriptine was increased to 10 mg daily. Conclusion Bromocriptine may stimulate dopamine receptors in cochlear cells with potential therapeutic role in patients with cochlear hydrops. There are no widely accepted and effective treatments for endolymphatic hydrops, and identifying potential new and efficacious therapeutics is of high relevance.

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