Introduction to “Understanding opioids within a developmental context”

2021 ◽  
pp. 107054
Author(s):  
Rina D. Eiden ◽  
Elizabeth M. Byrnes ◽  
Jennifer A. Willford
2020 ◽  
Vol 3 (1) ◽  
pp. 50-59
Author(s):  
Xu Jianqin

This article analyses the evolution of the mother–daughter relationship in China, and describes the mothering characteristics of four generations of women, which in sequence includes “foot-binding mothers”, “mothers after liberation”, “mothers after reform and opening up”, and “mothers who were only daughters”. Referring to Klein’s ideas about the mother–child relationship, especially those in her paper “Some reflections on ‘The Oresteia’ ”, the author tries to understand mothers and their impact on their daughters in these various periods of Chinese history, so as to explore the mutual influence of the mother–daughter relationship in particular, and the Chinese cultural and developmental context in general.


2021 ◽  
pp. 1-10
Author(s):  
Melody R. Altschuler ◽  
Robert F. Krueger

Abstract Traditional categorical approaches to classifying personality disorders are limited in important ways, leading to a shift in the field to dimensional approaches to conceptualizing personality pathology. Different areas of psychology – personality, developmental, and psychopathology – can be leveraged to understand personality pathology by examining its structure, development, and underlying mechanisms. However, an integrative model that encompasses these distinct lines of inquiry has not yet been proposed. In order to address this gap, we review the latest evidence for dimensional classification of personality disorders based on structural models of maladaptive personality traits, provide an overview of developmental theories of pathological personality, and summarize the Research Domain Criteria (RDoC) initiative, which seeks to understand underlying mechanisms of psychopathology. We conclude by proposing an integrative model of personality pathology development that aims to elucidate the developmental pathways of personality pathology and its underlying mechanisms.


Genetics ◽  
1997 ◽  
Vol 147 (3) ◽  
pp. 1139-1153 ◽  
Author(s):  
James V Price ◽  
Edward D Savenye ◽  
David Lum ◽  
Ashton Breitkreutz

The Drosophila epidermal growth factor receptor (EGFR) is a key component of a complex signaling pathway that participates in multiple developmental processes. We have performed and F1 screen for mutations that cause dominant enhancement of wing vein phenotypes associated with mutations in Egfr. With this screen, we have recovered mutations in Hairless (H), vein, groucho (gro), and three apparently novel loci. All of the E(Egfr)s we have identified show dominant interactions in transheterozygous combinations with each other and with alleles of N or Su(H), suggesting that they are involved in cross-talk between the N and EGFR signaling pathways. Further examination of the phenotypic interactions between Egfr, H, and gro revealed that reductions in Egfr activity enhanced both the bristle loss associated with H mutations, and the bristle hyperplasia and ocellar hypertrophy associated with gro mutations. Double mutant combinations of Egfr and gro hypomorphic alleles led to the formation of ectopic compound eyes in a dosage sensitive manner. Our findings suggest that these E(Egfr)s represent links between the Egfr and Notch signaling pathways, and that Egfr activity can either promote or suppress Notch signaling, depending on its developmental context.


2015 ◽  
Vol 2 (4) ◽  
pp. 256-266 ◽  
Author(s):  
J. Irene Harris ◽  
Crystal L. Park ◽  
Joseph M. Currier ◽  
Timothy J. Usset ◽  
Cory D. Voecks

2009 ◽  
Vol 45 (5) ◽  
pp. 1376-1388 ◽  
Author(s):  
G. A. Bradshaw ◽  
Theodora Capaldo ◽  
Lorin Lindner ◽  
Gloria Grow

2015 ◽  
Vol 18 (2) ◽  
pp. 234-247 ◽  
Author(s):  
George Henry Millard ◽  
Tim Hundleby

Purpose – The purpose of this paper is to look at the origins and development of organized crime in Brazil. Design/methodology/approach – The authors draw on their experience working in law enforcement for many years in Brazil. Findings – The paper outlines the major crimes committed by organized crime in Brazil and the structure of the main organization carrying them out. Research limitations/implications – The research concentrates on São Paolo and further research needs to be done. Originality/value – This is the first attempt to put the development of organized crime in Brazil into a historical and developmental context.


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