Solitary Fibrous Tumor of the Oral Cavity: Report of a Case

A case of solitary fibrous tumor is reported. Solitary fibrous tumor is a rare neoplasia characterized by the proliferation of fusiform cells of mesenchymal origin accounting for at least 2% of all soft tissue tumors. In this present case, the initial diagnosis was salivary gland tumor because of the location in the hard palate. Histologically, the tumor was composed by conjunctive tissue with proliferation of oval and fusiform cells. The immunohistochemical analysis was positive for CD34 and CD99. The lesion was treated by surgical resection. The clinical, imaging, histological and immunohistochemical data are discussed in this study. KeywordsSolitary fibrous tumor; Oral cavity; Hard palate; Differential diagnosis.

Download Full-text

Extrapleural Solitary fibrous tumor of the oral cavity: proliferation markers, tumor suppressor gene expression, and ultrastructural features

Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology ◽

10.1016/j.tripleo.2004.06.049 ◽

2004 ◽

Vol 98 (2) ◽

pp. 206

Author(s):

C. Flaitz ◽

B. Neville ◽

J. Hicks

Keyword(s):

Gene Expression ◽

Tumor Suppressor ◽

Oral Cavity ◽

Tumor Suppressor Gene ◽

Solitary Fibrous Tumor ◽

Suppressor Gene ◽

Proliferation Markers ◽

Fibrous Tumor ◽

Extrapleural Solitary Fibrous Tumor

Download Full-text

Solitary fibrous tumor of the oral cavity: the need for an extensive sampling for a correct diagnosis

Journal of Oral Pathology and Medicine ◽

10.1111/j.1600-0714.2007.00568.x ◽

2007 ◽

Vol 36 (9) ◽

pp. 538-542 ◽

Cited By ~ 17

Author(s):

Lorenzo Lo Muzio ◽

Massimo Mascolo ◽

Saverio Capodiferro ◽

Gianfranco Favia ◽

Eugenio Maiorano

Keyword(s):

Oral Cavity ◽

Solitary Fibrous Tumor ◽

Correct Diagnosis ◽

Fibrous Tumor

Download Full-text

Intraoral Removal of Huge Solitary Fibrous Tumor of the Oral Cavity after Embolization

Journal of Clinical Otolaryngology ◽

10.35420/jcohns.2008.19.1.114 ◽

2008 ◽

Vol 19 (1) ◽

pp. 114-118

Author(s):

Young Joo Jo ◽

Yun Su Yang ◽

Jong Seung Kim ◽

Ki Hwan Hong

Keyword(s):

Oral Cavity ◽

Solitary Fibrous Tumor ◽

Fibrous Tumor

Download Full-text

Large solitary fibrous tumor of the oral cavity—Report of a case

Pathology - Research and Practice ◽

10.1016/j.prp.2014.09.018 ◽

2014 ◽

Vol 210 (12) ◽

pp. 1064-1067 ◽

Cited By ~ 5

Author(s):

Denise Hélen Imaculada Pereira de Oliveira ◽

Assis Filipe Medeiros Albuquerque ◽

Matheus Dantas de Araújo Barreto ◽

Cassiano Francisco Weege Nonaka ◽

José Sandro Pereira da Silva ◽

...

Keyword(s):

Oral Cavity ◽

Solitary Fibrous Tumor ◽

Fibrous Tumor

Download Full-text

An Unusual Clinical Presentation of Solitary Fibrous Tumor in the Oral Cavity

Case Reports in Pathology ◽

10.1155/2017/4395049 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5

Author(s):

Everton Freitas de Morais ◽

Deborah Gondim Lambert Moreira ◽

Viviane Alves De Oliveira ◽

Rodrigo Rodrigues Rodrigues ◽

Adriano Rocha Germano ◽

...

Keyword(s):

Oral Cavity ◽

Solitary Fibrous Tumor ◽

Surgical Excision ◽

Excisional Biopsy ◽

Histopathological Analysis ◽

Normal Morphology ◽

S 100 ◽

History Of ◽

Fibrous Tumor

Solitary fibrous tumor is a rare neoplasm of mesenchymal origin that usually affects the pleura. This rarity becomes more relevant in the oral cavity since the clinical features are nonspecific. A 66-year-old female patient presented with a 3-month history of a swelling in the floor of the mouth, measuring 2 cm in greatest diameter, and pain symptomatology. Occlusal and panoramic radiographs showed no bone involvement. Ultrasonography of the submandibular and parotid salivary glands revealed normal morphology, dimensions, and echogenicity. During this exam, a nodular image of low echogenicity measuring about 2.7 × 1.8 cm was detected. An excisional biopsy was performed and histopathological analysis revealed a well-defined tumor-like lesion with alternation between hypercellular areas without a defined pattern and hypocellular areas. On immunohistochemistry, the tumor was positive for CD34 and CD99 and negative forα-SMA, S-100, and bcl-2. Combining the histopathological and immunohistochemical features, the diagnosis was solitary fibrous tumor. The patient is under periodical clinical follow-up and shows no signs of recurrence 7 months after surgical excision of the tumor. The combination of clinical-pathological and immunohistochemical features is necessary for the diagnosis.

Download Full-text