Biometric Analysis of Pigment Dispersion Syndrome Using Anterior Segment Optical Coherence Tomography

Ophthalmology ◽  
2011 ◽  
Vol 118 (8) ◽  
pp. 1563-1570 ◽  
Author(s):  
Florent Aptel ◽  
Sylvain Beccat ◽  
Vincent Fortoul ◽  
Philippe Denis
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Pigment Dispersion ◽  
Optical Coherence ◽  
Biometric Analysis ◽  
Pigment Dispersion Syndrome

scholarly journals Anterior segment optical coherence tomography documentation of Reverse Pupillary Block -A case of Pigment Dispersion Syndrome in a 10 year Old Child

2016 ◽  
Vol 15 (1) ◽  
pp. 34-39
Author(s):  
Devendra Maheshwari ◽  
Renagappa Ramakrishnan ◽  
Neelam Pawar
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Pigment Dispersion ◽  
Optical Coherence ◽  
Laser Peripheral Iridotomy ◽  
Pupillary Block ◽  
Laser Iridotomy ◽  
Pigment Dispersion Syndrome ◽  
History Of ◽  
Peripheral Iridotomy

We report a 10-year-old boy with unusually dense, bilateral central posterior capsule pigmentation associated with the characteristic clinical features of pigment dispersion syndrome, including Krukenberg’s spindle and dense trabecular pigmentation in both eyes. There was no history of trauma , laser or intraocular surgeries . The presence of posterior or backward bowing of iris suggested a reverse pupillary block mechanism of pigment dispersion syndrome. Nd Yag laser peripheral iridotomy was performed in both eyes to relieve reverse pupillary block. Anterior segment optical coherence tomography (AS-OCT) showed reversal of iris concavity after laser iridotomy.

scholarly journals PSEUDOEXFOLIATIVE SYNDROME AS A TRIGGER FOR PSEUDOEXFOLIATIVE GLAUCOMA

2021 ◽  
Vol 21 (2) ◽  
pp. 48-51
Author(s):  
Eddine Jouini Dhia ◽  
I. M. Bezkorovaуna
Keyword(s):  
Optical Coherence Tomography ◽  
Open Angle Glaucoma ◽  
Anterior Segment ◽  
Retinal Nerve Fibre Layer ◽  
Pigment Dispersion ◽  
Optical Coherence ◽  
Drug Induced ◽  
Pseudoexfoliative Glaucoma ◽  
Diagnostic Measures ◽  
Pigment Dispersion Syndrome

Glaucoma is one of the leading causes of blindness and disability worldwide. Pseudoexfoliative glaucoma is known to be the most aggressive and difficult-to-treat form of secondary glaucoma. According to the literature, pseudoexfoliative glaucoma occurs in 25-30% of cases among all open-angle glaucoma. The recent studies have established that a quarter of patients with pseudoexfoliative glaucoma are blind in one eye, and 7% are blind in both eyes. Risk factors for glaucoma include systemic and ophthalmic factors, one of which is the development of pseudoexfoliative syndrome. In patients with pseudoexfoliative syndrome, glaucoma occurs 20 times more often than in the general population of the same age. The purpose of this research is to study the informativeness of individual phenomena of pseudoexfoliative syndrome (PES) in order to improve early diagnosis and prevention of pseudoexfoliative glaucoma. The study included 114 patients diagnosed as having PES. Exclusion criteria were as follows: age up to 45 years, surgery on the eyeball, a history of disease (iridocyclitis, uveitis, corneal pathology, and traumatic eye disease), pigment dispersion syndrome. Along with the standard set of diagnostic measures, patients underwent biomicroscopy in the conditions of maximum drug-induced mydriasis, gonioscopic examination; the proportion of patients was examined by optical coherence tomography (SD-OCT Topson 3D oct-2000FA Plus (version 7/21/003/0)). The study revealed signs of pseudoexfoliative syndrome (deposition of pseudoexfoliative material on various structures of the anterior segment of the eye) in 100% of cases. Higher values of intraocular pressure (from 29 to 34 mm Hg) were found in the patients with elements of blocking the angle of the anterior chamber (narrowing or closing the angle, increased pigmentation and the presence of draining exfoliative conglomerates). The optical coherence tomography study revealed a thinning of the retinal nerve fibres (33.60 ± 0.43 μm), a significant thinning of retinal nerve fibre layer in patients with pseudoexfoliative syndrome and even more significant thinning in 29 patients diagnosed with pseudoexfoliative glaucoma. Thus, we can conclude knowing the microsymptoms of the disease, mandatory investigating the conditions of the maximum drug-induced mydriasis can contribute to detect pseudoexfoliative syndrome even in the initial stages and thus to prevent the development of pseudoexfoliative glaucoma.

Anterior segment imaging using optical coherence tomography in atypical pigment dispersion syndrome

2009 ◽  
Vol 44 (5) ◽  
pp. 612-614
Author(s):  
Consuelo Pérez-Rico ◽  
María Ángeles Montes-Mollón ◽  
Javier Paz-Moreno ◽  
María Castro-Rebollo ◽  
Javier Benítez-Herreros
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Pigment Dispersion ◽  
Optical Coherence ◽  
Pigment Dispersion Syndrome ◽  
Anterior Segment Imaging

Utility of the Anterior Segment Optical Coherence Tomography for Measurements of Central Corneal Thickness

2007 ◽  
Vol 48 (12) ◽  
pp. 1643 ◽  
Author(s):  
Hyoung Sub Shim ◽  
Chul Young Choi ◽  
Hee Gyung Lee ◽  
Myoung Joon Kim ◽  
Hung Won Tchah
Keyword(s):  
Optical Coherence Tomography ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Optical Coherence

Pediatric Free-floating Anterior Chamber Cyst of the Iris Pigment Epithelium

2018 ◽  
Vol 1 ◽  
pp. 3
Author(s):  
Joshua S Agranat ◽  
Yoshihiro Yonekawa
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Incidental Finding ◽  
Pigment Epithelium ◽  
Anterior Segment ◽  
Ultrasound Biomicroscopy ◽  
Optical Coherence ◽  
Visual Axis ◽  
Associated Malignancy ◽  
Anatomic Locations

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.

scholarly journals Structural changes of corneal epithelium in belantamab-associated superficial keratopathy using anterior segment optical coherence tomography

2021 ◽  
pp. 101133
Author(s):  
Wataru Matsumiya ◽  
Irmak Karaca ◽  
Hashem Ghoraba ◽  
Amir Akhavanrezayat ◽  
Azadeh Mobasserian ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Corneal Epithelium ◽  
Structural Changes ◽  
Anterior Segment ◽  
Optical Coherence

Evaluation of Intraocular Lens Tilt With Anterior Segment Optical Coherence Tomography

2011 ◽  
Vol 151 (3) ◽  
pp. 406-412.e2 ◽  
Author(s):  
Dhivya Ashok Kumar ◽  
Amar Agarwal ◽  
Gaurav Prakash ◽  
Soosan Jacob ◽  
Yoga Saravanan ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Lens ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Intraocular Lens Tilt

scholarly journals The Use of Anterior-Segment Optical-Coherence Tomography for the Assessment of the Iridocorneal Angle and Its Alterations: Update and Current Evidence

2021 ◽  
Vol 10 (2) ◽  
pp. 231
Author(s):  
Giacinto Triolo ◽  
Piero Barboni ◽  
Giacomo Savini ◽  
Francesco De Gaetano ◽  
Gaspare Monaco ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Clinical Relevance ◽  
Anterior Segment ◽  
Angle Closure ◽  
Current Evidence ◽  
Optical Coherence ◽  
Iridocorneal Angle ◽  
Wide Range

The introduction of anterior-segment optical-coherence tomography (AS-OCT) has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly. The aim of the present review is to summarize the current evidence supporting the use of AS-OCT for the diagnosis and follow-up of several iridocorneal-angle and anterior-chamber alterations, focusing on the advantages and downsides of this technology.

scholarly journals Non-malignant conjunctival epithelial masses with ocular surface squamous neoplasia-like optical coherence tomography features

2021 ◽  
Author(s):  
Ágnes Füst ◽  
Jeannette Tóth ◽  
László Imre ◽  
Zoltán Zsolt Nagy
Keyword(s):  
Optical Coherence Tomography ◽  
Ocular Surface ◽  
Anterior Segment ◽  
Histological Diagnosis ◽  
Optical Coherence ◽  
Ocular Surface Squamous Neoplasia ◽  
Ocular Coherence Tomography ◽  
Maximal Thickness ◽  
Epithelial Lesions ◽  
Mass Lesions

Abstract Purpose To observe and describe the anterior segment optical coherence tomography features of limbally localised non-malignant epithelial mass lesions Methods Thirteen patients (age: 66.9 ± 16.3 years) with conjunctival mass suggesting ocular surface squamous neoplasia with biomicroscopic examination were imaged using anterior segment ocular coherence tomography (anterior segment optical coherence tomography)/Cirrus HD-OCT, Model 4000, Carl Zeiss Meditec, Inc., Dublin, CA, and Spectralis HRA + OCT system, Heidelberg Engineering, Vista, CA/. Cases with ocular surface squamous neoplasia-like anterior segment optical coherence tomography (hyperreflective, thickened epithelium and an abrupt transition from normal to abnormal) were included in the study. Maximal thickness of the epithelium was measured. Histological diagnosis was gained from an excisional or incisional biopsy or impression cytology specimens. Results In six patients (age: 68.5 ± 15.4 years) with ocular surface squamous neoplasia-like anterior segment optical coherence tomography features, the histological diagnosis was other than ocular surface squamous neoplasia (papilloma, parakeratosis and a keratotic plaque with mild dysplasia), and ocular surface squamous neoplasia in seven cases (age: 65.6 ± 18.0 years). The maximal epithelial thickness was between 250 and 859 µm in non-ocular surface squamous neoplasia cases and between 252 and 596 µm in ocular surface squamous neoplasia cases. Conclusion Non-malignant epithelial lesions can mimic ocular surface squamous neoplasia on anterior segment optical coherence tomography.

scholarly journals Diagnosing Paraproteinemic Keratopathy: A Case Report

2021 ◽  
pp. 337-343
Author(s):  
Eugenie Mok ◽  
Ka Wai Kam ◽  
Anthony J. Aldave ◽  
Alvin L. Young
Keyword(s):  
Optical Coherence Tomography ◽  
Genetic Testing ◽  
Serum Protein ◽  
Molecular Genetic ◽  
Anterior Segment ◽  
Protein Electrophoresis ◽  
Serum Protein Electrophoresis ◽  
Optical Coherence ◽  
Molecular Genetic Testing ◽  
Corneal Opacities

A 65-year-old man presented with bilateral, painless, progressive blurring of vision over 9 years. Slit-lamp examination revealed bilateral subepithelial corneal opacities in clusters located at the mid-periphery. Anterior segment optical coherence tomography, in vivo confocal microscopy (IVCM), serum protein electrophoresis, and molecular genetic testing were performed to evaluate the cause of corneal opacities. Anterior segment optical coherence tomography revealed a band-like, hyperreflective lesion in the Bowman layer and anterior stroma of both corneas. IVCM revealed hyperreflective deposits in the epithelium, anterior stroma, and endothelium. Serum protein electrophoresis identified the presence of paraproteins (immunoglobulin kappa), and molecular genetic testing revealed absence of mutations in the transforming growth factor beta-induced gene (<i>TGFBI</i>) and collagen type XVII alpha 1 gene (<i>COL17A1</i>). The ocular diagnosis of paraproteinemic keratopathy eventually led to a systemic diagnosis of monoclonal gammopathy of undetermined significance by our hematologist/oncologist. Paraproteinemic keratopathy is a rare differential diagnosis in patients with bilateral corneal opacities and therefore may be misdiagnosed as corneal dystrophy or neglected as scars. In patients with bilateral corneal opacities of unknown cause, serological examination, adjunct anterior segment imaging, and molecular genetic testing play a role in establishing the diagnosis.

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