Ocular Adverse Effects of Infigratinib, a New Fibroblast Growth Factor Receptor Tyrosine Kinase Inhibitor

Ophthalmology ◽

10.1016/j.ophtha.2020.08.026 ◽

2020 ◽

Author(s):

M. Teresa Magone ◽

Iris R. Hartley ◽

Edmond Fitzgibbon ◽

Rachel Bishop ◽

Mike Arango ◽

...

Keyword(s):

Growth Factor ◽

Adverse Effects ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Fibroblast Growth Factor ◽

Receptor Tyrosine Kinase ◽

Fibroblast Growth Factor Receptor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Re: Magone et al.: Ocular adverse effects of infigratinib, a new fibroblast growth factor receptor tyrosine kinase inhibitor (Ophthalmology. 2021;128:624–626)

Ophthalmology ◽

10.1016/j.ophtha.2021.05.012 ◽

2021 ◽

Author(s):

Jasmine H. Francis ◽

Julia Canestraro ◽

David H. Abramson

Keyword(s):

Growth Factor ◽

Adverse Effects ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Fibroblast Growth Factor ◽

Receptor Tyrosine Kinase ◽

Fibroblast Growth Factor Receptor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Safety, pharmacokinetic, and pharmacodynamics of erdafitinib, a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, in patients with advanced or refractory solid tumors

Investigational New Drugs ◽

10.1007/s10637-017-0514-4 ◽

2017 ◽

Vol 36 (3) ◽

pp. 424-434 ◽

Author(s):

Tomohiro Nishina ◽

Shunji Takahashi ◽

Ryota Iwasawa ◽

Hidehisa Noguchi ◽

Masayuki Aoki ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Fibroblast Growth Factor ◽

Solid Tumors ◽

Fibroblast Growth Factor Receptor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Bortezomib, Dexamethasone, and Fibroblast Growth Factor Receptor 3-Specific Tyrosine Kinase Inhibitor in t(4;14) Myeloma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-08-1612 ◽

2009 ◽

Vol 15 (2) ◽

pp. 520-531 ◽

Author(s):

G. Bisping ◽

D. Wenning ◽

M. Kropff ◽

D. Gustavus ◽

C. Muller-Tidow ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Metabolism and disposition in rats, dogs, and humans of erdafitinib, an orally administered potent pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor

Xenobiotica ◽

10.1080/00498254.2020.1821123 ◽

2020 ◽

Vol 51 (2) ◽

pp. 177-193

Author(s):

Ellen Scheers ◽

Carine Borgmans ◽

Chi Keung ◽

Hilde Bohets ◽

Inneke Wynant ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Abstract 3858: Gains in FGF19 are predictive of response to the fibroblast growth factor receptor (FGFR) small molecule tyrosine kinase inhibitor BGJ 398in vitro

10.1158/1538-7445.am2012-3858 ◽

2012 ◽

Author(s):

Richard S. Finn ◽

Alex Aleshin ◽

Danyun Zhao ◽

Lee Anderson ◽

Charles Ginther ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Fibroblast Growth Factor ◽

Small Molecule ◽

Fibroblast Growth Factor Receptor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Abstract 3244: Treatment of endometrial cancer cells with a new small tyrosine kinase inhibitor targeting mutated fibroblast growth factor receptor-2

10.1158/1538-7445.am2017-3244 ◽

2017 ◽

Author(s):

Sebastien Taurin ◽

Chieh-Hsiang Yang ◽

Maria Reyes ◽

Sungpil Cho ◽

Elke A. Jarboe ◽

...

Keyword(s):

Endometrial Cancer ◽

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cancer Cells ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

Journal of Medicinal Chemistry ◽

10.1021/jm2006222 ◽

2011 ◽

Vol 54 (20) ◽

pp. 7066-7083 ◽

Author(s):

Vito Guagnano ◽

Pascal Furet ◽

Carsten Spanka ◽

Vincent Bordas ◽

Mickaël Le Douget ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Fibroblast Growth Factor ◽

Receptor Tyrosine Kinase ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Selective Inhibitor ◽

Fibroblast Growth ◽

Receptor Family

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Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome

Cellular Signalling ◽

10.1016/j.cellsig.2017.10.003 ◽

2018 ◽

Vol 42 ◽

pp. 144-154 ◽

Author(s):

Lukas Balek ◽

Pavel Nemec ◽

Peter Konik ◽

Michaela Kunova Bosakova ◽

Miroslav Varecha ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Fibroblast Growth Factor ◽

Receptor Tyrosine Kinase ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Proteomic Analyses

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Novel inhibitor for fibroblast growth factor receptor tyrosine kinase

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2007.06.058 ◽

2007 ◽

Vol 17 (17) ◽

pp. 4812-4818 ◽

Author(s):

Naparat Kammasud ◽

Chantana Boonyarat ◽

Satoshi Tsunoda ◽

Hiroaki Sakurai ◽

Ikuo Saiki ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Fibroblast Growth Factor ◽

Receptor Tyrosine Kinase ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth

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Identification of tyrosines 154 and 307 in the extracellular domain and 653 and 766 in the intracellular domain as phosphorylation sites in the heparin-binding fibroblast growth factor receptor tyrosine kinase (flg )

Protein Science ◽

10.1002/pro.5560020109 ◽

1993 ◽

Vol 2 (1) ◽

pp. 86-92 ◽

Author(s):

Jinzhao Hou ◽

Kerstin Mckeehan ◽

Mikio Kan ◽

John W. Crabb ◽

Wallace L. Mckeehan ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Fibroblast Growth Factor ◽

Receptor Tyrosine Kinase ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Phosphorylation Sites ◽

Fibroblast Growth ◽

Heparin Binding ◽

Intracellular Domain

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