Metabolism and disposition in rats, dogs, and humans of erdafitinib, an orally administered potent pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Safety, pharmacokinetic, and pharmacodynamics of erdafitinib, a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, in patients with advanced or refractory solid tumors

Investigational New Drugs ◽

10.1007/s10637-017-0514-4 ◽

2017 ◽

Vol 36 (3) ◽

pp. 424-434 ◽

Cited By ~ 32

Author(s):

Tomohiro Nishina ◽

Shunji Takahashi ◽

Ryota Iwasawa ◽

Hidehisa Noguchi ◽

Masayuki Aoki ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Solid Tumors ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Bortezomib, Dexamethasone, and Fibroblast Growth Factor Receptor 3-Specific Tyrosine Kinase Inhibitor in t(4;14) Myeloma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-08-1612 ◽

2009 ◽

Vol 15 (2) ◽

pp. 520-531 ◽

Cited By ~ 23

Author(s):

G. Bisping ◽

D. Wenning ◽

M. Kropff ◽

D. Gustavus ◽

C. Muller-Tidow ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Ocular Adverse Effects of Infigratinib, a New Fibroblast Growth Factor Receptor Tyrosine Kinase Inhibitor

Ophthalmology ◽

10.1016/j.ophtha.2020.08.026 ◽

2020 ◽

Author(s):

M. Teresa Magone ◽

Iris R. Hartley ◽

Edmond Fitzgibbon ◽

Rachel Bishop ◽

Mike Arango ◽

...

Keyword(s):

Growth Factor ◽

Adverse Effects ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Re: Magone et al.: Ocular adverse effects of infigratinib, a new fibroblast growth factor receptor tyrosine kinase inhibitor (Ophthalmology. 2021;128:624–626)

Ophthalmology ◽

10.1016/j.ophtha.2021.05.012 ◽

2021 ◽

Author(s):

Jasmine H. Francis ◽

Julia Canestraro ◽

David H. Abramson

Keyword(s):

Growth Factor ◽

Adverse Effects ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Abstract 3858: Gains in FGF19 are predictive of response to the fibroblast growth factor receptor (FGFR) small molecule tyrosine kinase inhibitor BGJ 398in vitro

10.1158/1538-7445.am2012-3858 ◽

2012 ◽

Cited By ~ 5

Author(s):

Richard S. Finn ◽

Alex Aleshin ◽

Danyun Zhao ◽

Lee Anderson ◽

Charles Ginther ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Small Molecule ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Abstract 3244: Treatment of endometrial cancer cells with a new small tyrosine kinase inhibitor targeting mutated fibroblast growth factor receptor-2

10.1158/1538-7445.am2017-3244 ◽

2017 ◽

Cited By ~ 3

Author(s):

Sebastien Taurin ◽

Chieh-Hsiang Yang ◽

Maria Reyes ◽

Sungpil Cho ◽

Elke A. Jarboe ◽

...

Keyword(s):

Endometrial Cancer ◽

Growth Factor ◽

Tyrosine Kinase ◽

Cancer Cells ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Increased interdigitation zone visibility on optical coherence tomography following systemic fibroblast growth factor receptor 1‐3 tyrosine kinase inhibitor anticancer therapy

Clinical and Experimental Ophthalmology ◽

10.1111/ceo.13940 ◽

2021 ◽

Author(s):

Jason Charng ◽

Mary S. Attia ◽

Sukanya Arunachalam ◽

Wei‐Sen Lam ◽

Jenette Creaney ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Growth Factor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Anticancer Therapy ◽

Fibroblast Growth ◽

Interdigitation Zone

Acidic fibroblast growth factor receptor purified from bovine liver is a novel protein tyrosine kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)46244-2 ◽

1990 ◽

Vol 265 (27) ◽

pp. 16455-16463 ◽

Cited By ~ 6

Author(s):

M D Kuo ◽

S S Huang ◽

J S Huang

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Protein Tyrosine Kinase ◽

Growth Factor Receptor ◽

Bovine Liver ◽

Fibroblast Growth ◽

Acidic Fibroblast Growth Factor ◽

Novel Protein

Fibroblast Growth Factor 19–Mediated Up‐regulation of SYR‐Related High‐Mobility Group Box 18 Promotes Hepatocellular Carcinoma Metastasis by Transactivating Fibroblast Growth Factor Receptor 4 and Fms‐Related Tyrosine Kinase 4

Hepatology ◽

10.1002/hep.30951 ◽

2020 ◽

Vol 71 (5) ◽

pp. 1712-1731 ◽

Cited By ~ 7

Author(s):

Jie Chen ◽

Feng Du ◽

Yunzhi Dang ◽

Xiaowei Li ◽

Meirui Qian ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Tyrosine Kinase ◽

Growth Factor Receptor ◽

High Mobility ◽

Fibroblast Growth ◽

Carcinoma Metastasis ◽

Fibroblast Growth Factor 19

A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia

Nature Genetics ◽

10.1038/ng0795-357 ◽

1995 ◽

Vol 10 (3) ◽

pp. 357-359 ◽

Cited By ~ 325

Author(s):

Gary A. Bellus ◽

Iain McIntosh ◽

E. Anne Smith ◽

Arthur S. Aylsworth ◽

Ilkka Kaitila ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Recurrent Mutation ◽

Tyrosine Kinase Domain ◽