An ellipsometric surface plasmon resonance system for quantitatively determining the normal of a sensor surface and multi-channel measurement

2013 ◽  
Vol 294 ◽  
pp. 8-12 ◽  
Author(s):  
Chien-Yuan Han ◽  
Chien-Wei Luo
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Sensor Surface ◽  
Resonance System ◽  
Channel Measurement

scholarly journals Magneto-Optic Surface Plasmon Resonance Ti/Au/Co/Au/Pc Configuration and Sensitivity

2018 ◽  
Author(s):  
Conrad Rizal
Keyword(s):  
Magnetic Field ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Protective Layer ◽  
Surface Cleaning ◽  
Water Medium ◽  
Sensor Surface ◽  
X Ray ◽  
Magneto Optic

Magneto-optic surface plasmon resonance (MOSPR) based sensors are highly attractive as next generation biosensors. However, these sensors suffer from oxidation leading to degradation of performance, reproducibility of the sensor surface because of the difficulty of removing adsorbed materials, and degradation of sensor surface during surface cleaning, and these limit their applications. In this paper, I propose MOSPR-based biosensors with 0 to 15 nm thick inert polycarbonate laminate plastic as a protective layer and theoretically demonstrate the practicability of our approach in water-medium for three different probing samples: ethanol, propanol, and pentanol. I also investigate microstructure and magnetic properties. The chemical composition and layered information of the sensor are investigated using X-ray reflectivity and X-ray diffraction analyses and these show distinct fcc-Au (111) phases, as dominated by the higher density of conduction electrons in Au as compared to Co. The magnetic characterization measured with the in-plane magnetic field to the sensor surface for both the as-deposited and annealed multilayers showed isotropic easy axis magnetization parallel to the multilayer interface at a saturating magnetic field of <100 Oe. The sensor showed a maximum sensitivity of 5.5 × 104%/RIU for water-ethanol media and the highest detection level of 2.5 × 10−8 for water-pentanol media as the protective layer is increased from 0 to 15 nm.c

Research on Influencing Factors of Surface Plasmon Resonance Glucose Detection Based on D-Galactose/D-Glucose Protein Immobilizied by Amine Coupling Method

2010 ◽  
Author(s):  
Peng Wu ◽  
Dachao Li ◽  
Jingxin Zhang ◽  
Bing Song ◽  
Kexin Xu
Keyword(s):  
Mass Transfer ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Glucose Concentration ◽  
Interstitial Fluid ◽  
Transfer Effect ◽  
Sensor Surface ◽  
Mass Transfer Effect ◽  
Spr Sensor

Prediction of blood glucose based on measuring the glucose concentration in interstitial fluid is an effectively way to control diabetes. A surface plasmon resonance (SPR) system based on a miniature integrated SPR sensor is set up in this paper to measure the glucose concentration in interstitial fluid, and the D-galactose/D-glucose Binding Protein (GGBP) which can specifically absorb glucose is immobilized onto the SPR sensor surface by amine coupling method for higher sensitivity. The experiment result is affected by various factors, such as the grime on sensor surface, baseline, flow velocity, mass transfer effect, temperature, protein activity, bubbles. In this paper these factors are studied systemically by experiments and some solutions are proposed accordingly: (1) Make sure the sensor surface is clean before it is used. (2) Dynamic baseline can provide the best baseline location during the measurement. (3) Flow velocity of 10uL/min-30uL/min is supposed to be chosen. (4) The density of protein immobilized on the sensor surface should maintain lower to avoid the mass transfer effect. (5) Higher response is got when the temperature is between 26°C and 30°C and it is important to keep temperature constant during the experiment. (6) The protein should be preserved with a proper way and make sure it is active during the measurement. (7) The sample should be degassed and filtered before the experiment and make sure there is no air in the pipeline. Through optimizing the experiment conditions, the sensitivity and stability of the measurement are improved.

Dendrimer-Functionalized Self-Assembled Monolayers as a Surface Plasmon Resonance Sensor Surface

Langmuir ◽  
2004 ◽  
Vol 20 (16) ◽  
pp. 6808-6817 ◽  
Author(s):  
Sonny S. Mark ◽  
Neelakantapillai Sandhyarani ◽  
Changcheng Zhu ◽  
Christine Campagnolo ◽  
Carl A. Batt
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Self Assembled Monolayers ◽  
Surface Plasmon Resonance Sensor ◽  
Sensor Surface ◽  
Resonance Sensor ◽  
Assembled Monolayers ◽  
Self Assembled

A Novel Method for the Assessment of Targeted PEI-Based Nanoparticle Binding Based on a Static Surface Plasmon Resonance System

2013 ◽  
Vol 86 (14) ◽  
pp. 6827-6835 ◽  
Author(s):  
Sabrina Höbel ◽  
Doru Vornicescu ◽  
Marius Bauer ◽  
Dagmar Fischer ◽  
Michael Keusgen ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Resonance System ◽  
Novel Method

Surface Plasmon Resonance Signal Amplification Using Secondary Antibody Interaction for Illegal Compound Detection

2020 ◽  
Vol 845 ◽  
pp. 103-108
Author(s):  
Suherman ◽  
Dulal Chandra Kabiraz ◽  
Kinichi Morita ◽  
Toshikazu Kawaguchi
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Competitive Inhibition ◽  
Coupling Reaction ◽  
Primary Antibody ◽  
Antibody Detection ◽  
Secondary Antibody ◽  
Sensor Surface ◽  
Spr Sensor

The development of highly selective and sensitive surface plasmon resonance (SPR) immunoassay for the rapid detection of illegal compound using secondary antibody interaction labelled nanoparticle was conducted. For the construction of SPR sensor surface, the illegal compound (clenbuterol) was immobilized as antigen onto gold succinimide-terminated monolayer to perform amide-coupling reaction. In order to avoid non-specific reaction, the blocking agent (ethanol amine) was injected to the SPR system. Furthermore, indirect competitive inhibition method was employed in the detection of clenbuterol. In this work, the antibody solution (PBS solution containing clenbuterol antibody) premixed with a sample solution (PBS solution containing antigen) before the injection into the sensing system. As the premixed solution flowed over the sensor surface, the SPR senses the dielectric constant change at the interface due to the binding of the unreacted primary antibody to antigen-immobilized on the sensor surface. After this primary antibody detection, secondary antibody was injected to the SPR sensor surface. Here, we compared the signal difference of secondary antibody injection labelled Au nanoparticles (d = 40 nm). For the regeneration of the sensor surface, 0.1 M NaOH was used, so primary and secondary antibodies could be detached from the sensor surface. According to the indirect competitive inhibition method, it was found that the sensitivity for clenbuterol detection was enhanced from 2.5 ppt to 0.07 ppt.

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