Could the biological robustness of low level laser therapy (Photobiomodulation) impact its use in the management of mucositis in head and neck cancer patients

Oral Oncology ◽  
2016 ◽  
Vol 54 ◽  
pp. 7-14 ◽  
Author(s):  
Stephen T. Sonis ◽  
Sepehr Hashemi ◽  
Joel B. Epstein ◽  
Raj G. Nair ◽  
Judith E. Raber-Durlacher
Oral Oncology ◽  
2016 ◽  
Vol 52 ◽  
pp. 85-90 ◽  
Author(s):  
Héliton S. Antunes ◽  
Luciene Fontes Schluckebier ◽  
Daniel Herchenhorn ◽  
Isabele A. Small ◽  
Carlos M.M. Araújo ◽  
...  

2015 ◽  
Vol 47 (4) ◽  
pp. 296-305 ◽  
Author(s):  
Angélica F. Oton-Leite ◽  
Geisa Badauy L. Silva ◽  
Marília O. Morais ◽  
Tarcília A. Silva ◽  
Cláudio R. Leles ◽  
...  

Author(s):  
Rene Fischlechner ◽  
Barbara Kofler ◽  
Volker Hans Schartinger ◽  
Jozsef Dudas ◽  
Herbert Riechelmann

2016 ◽  
Vol 49 (2) ◽  
pp. 86-91 ◽  
Author(s):  
Fernanda Aurora Stabile Gonnelli ◽  
Luiz Felipe Palma ◽  
Adelmo José Giordani ◽  
Aline Lima Silva Deboni ◽  
Rodrigo Souza Dias ◽  
...  

Abstract Objective: To determine whether low-level laser therapy can prevent salivary hypofunction after radiotherapy and chemotherapy in head and neck cancer patients. Materials and Methods: We evaluated 23 head and neck cancer patients, of whom 13 received laser therapy and 10 received clinical care only. An InGaAlP laser was used intra-orally (at 660 nm and 40 mW) at a mean dose of 10.0 J/cm2 and extra-orally (at 780 nm and 15 mW) at a mean dose of 3.7 J/cm2, three times per week, on alternate days. Stimulated and unstimulated sialometry tests were performed before the first radiotherapy and chemotherapy sessions (N0) and at 30 days after the end of treatment (N30). Results: At N30, the mean salivary flow rates were significantly higher among the laser therapy patients than among the patients who received clinical care only, in the stimulated and unstimulated sialometry tests (p = 0.0131 and p = 0.0143, respectively). Conclusion: Low-level laser therapy, administered concomitantly with radiotherapy and chemotherapy, appears to mitigate treatment-induced salivary hypofunction in patients with head and neck cancer.


Head & Neck ◽  
2011 ◽  
Vol 34 (3) ◽  
pp. 398-404 ◽  
Author(s):  
Angélica Ferreira Oton-Leite ◽  
Annelise Carrilho Corrêa de Castro ◽  
Marília Oliveira Morais ◽  
Juliana Castro Dourado Pinezi ◽  
Cláudio Rodrigues Leles ◽  
...  

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