Gunshot induced injuries in orthopaedic trauma research. A bibliometric analysis of the most influential literature

This review describes the development, advantages and disadvantages, and applications of the Patient-Reported Outcome Measurement Information System (PROMIS) in orthopaedic trauma. PROMIS is a useful tool for quantifying outcomes in orthopedic trauma. It allows measurement of outcomes across multiple domains while minimizing administration time. PROMIS also reliably identifies clinical, social, and psychological risk factors for poor outcomes across a variety of orthopaedic injuries and disease states. However, PROMIS lacks specificity for certain anatomic regions and validation for mental health outcomes. It also is limited by ceiling effects in certain active patient populations. Orthopaedic traumatologists should be familiar with PROMIS, as its use is increasing and it is a valuable tool that can aid in clinical decision making.

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Virtual Structural Analysis of Tibial Fracture Healing from Low-Dose Clinical CT Scans

10.31224/osf.io/7c8kz ◽

2018 ◽

Author(s):

Peter Schwarzenberg ◽

Hannah L. Dailey

Keyword(s):

Structural Analysis ◽

Fracture Healing ◽

Bone Healing ◽

Structural Integrity ◽

Torsional Rigidity ◽

Torsion Test ◽

Ct Scans ◽

Orthopaedic Trauma ◽

Element Analysis ◽

Trauma Research

Quantitative assessment of bone fracture healing remains a significant challenge in orthopaedic trauma research. Accordingly, we developed a new technique for assessing bone healing using virtual mechano-structural analysis of computed tomography (CT) scans. CT scans from 19 fractured human tibiae at 12 weeks after surgery were segmented and prepared for finite element analysis (FEA). Boundary conditions were applied to the models to simulate a torsion test that is commonly used to access the structural integrity of long bones in animal models of fracture healing. The output of each model was the virtual torsional rigidity (VTR) of the healing zone, normalized to the torsional rigidity of each patient’s virtually reconstructed tibia. This provided a structural measure to track the percentage of healing each patient had undergone. Callus morphometric measurements were also collected from the CT scans. Results showed that at 12 weeks post-op, more than 75% of patients achieved a normalized VTR (torsional rigidity relative to uninjured bone) of 85% or above. The predicted intact torsional rigidities compared well with published cadaveric data. Across all patients, callus volume and density were weakly and non-significantly correlated with normalized VTR and time to clinical union. Conversely, normalized VTR was significantly correlated with time to union (R2 = 0.383, p = 0.005). This suggests that fracture scoring methods based on the visual appearance of callus may not accurately predict mechanical integrity. The image-based structural analysis presented here may be a useful technique for assessment of bone healing in orthopaedic trauma research.

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Orthopaedic trauma research priority-setting exercise and development of a research network

Injury ◽

10.1016/j.injury.2010.03.026 ◽

2010 ◽

Vol 41 (7) ◽

pp. 763-767 ◽

Cited By ~ 8

Author(s):

K.M. Willett ◽

B. Gray ◽

C.G. Moran ◽

P.V. Giannoudis ◽

I. Pallister

Keyword(s):

Priority Setting ◽

Research Network ◽

Orthopaedic Trauma ◽

Trauma Research ◽

Research Priority ◽

Priority Setting Exercise

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Is PROMIS the new standard for patient-reported outcomes measures in orthopaedic trauma research?

Injury ◽

10.1016/j.injury.2019.10.076 ◽

2020 ◽

Vol 51 ◽

pp. S43-S50 ◽

Cited By ~ 1

Author(s):

Nathan N O'Hara ◽

John T. Richards ◽

Archie Overmann ◽

Gerard P. Slobogean ◽

Niek S. Klazinga

Keyword(s):

Patient Reported Outcomes ◽

Orthopaedic Trauma ◽

Trauma Research ◽

Outcomes Measures ◽

Patient Reported

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Predicting completion of follow-up in prospective orthopaedic trauma research

OTA International ◽

10.1097/oi9.0000000000000047 ◽

2019 ◽

Vol 2 (4) ◽

pp. e047

Author(s):

Graham K.J. Sleat ◽

Kelly A. Lefaivre ◽

Henry M. Broekhuyse ◽

Peter J. O’Brien

Keyword(s):

Orthopaedic Trauma ◽

Trauma Research

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How to use the patient-reported outcomes measurement information system (PROMIS) in international orthopaedic trauma research: a practical approach

Injury ◽

10.1016/j.injury.2021.03.021 ◽

2021 ◽

Author(s):

Diederik O. Verbeek ◽

Caroline B. Terwee ◽

Lotte Haverman

Keyword(s):

Information System ◽

Patient Reported Outcomes ◽

Practical Approach ◽

Measurement Information ◽

Orthopaedic Trauma ◽

Outcomes Measurement ◽

Trauma Research ◽

International Orthopaedic ◽

Patient Reported ◽

Measurement Information System

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Orthopaedic trauma research priority setting exercise and development of a research network

Injury Extra ◽

10.1016/j.injury.2009.06.209 ◽

2009 ◽

Vol 40 (10) ◽

pp. 199

Author(s):

K. Willett ◽

B. Gray ◽

C. Moran ◽

P. Giannoudis ◽

I. Pallister

Keyword(s):

Priority Setting ◽

Research Network ◽

Orthopaedic Trauma ◽

Trauma Research ◽

Research Priority ◽

Priority Setting Exercise

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A patient-centered composite endpoint weighting technique for orthopaedic trauma research

BMC Medical Research Methodology ◽

10.1186/s12874-019-0885-7 ◽

2019 ◽

Vol 19 (1) ◽

Author(s):

Ugochukwu N. Udogwu ◽

Andrea Howe ◽

Katherine Frey ◽

Marckenley Isaac ◽

Daniel Connelly ◽

...

Keyword(s):

Clinical Outcomes ◽

Composite Endpoint ◽

Trauma Patients ◽

Relative Importance ◽

Orthopaedic Trauma ◽

Patient Centered ◽

Trauma Research ◽

Knee Amputation ◽

Deep Surgical Site Infection ◽

Weighting Technique

Abstract Background This study aimed to address the current limitations of the use of composite endpoints in orthopaedic trauma research by quantifying the relative importance of clinical outcomes common to orthopaedic trauma patients and use those values to develop a patient-centered composite endpoint weighting technique. Methods A Best-Worst Scaling choice experiment was administered to 396 adult surgically-treated fracture patients. Respondents were presented with ten choice sets, each consisting of three out of ten plausible clinical outcomes. Hierarchical Bayesian modeling was used to determine the utilities associated with the outcomes. Results Death was the outcome of greatest importance (mean utility = − 8.91), followed by above knee amputation (− 7.66), below knee amputation (− 6.97), severe pain (− 5.90), deep surgical site infection (SSI) (− 5.69), bone healing complications (− 5.20), and moderate pain (− 4.59). Mild pain (− 3.30) and superficial SSI (− 3.29), on the other hand, were the outcomes of least importance to respondents. Conclusion This study revealed that patients’ relative importance towards clinical outcomes followed a logical gradient, with distinct and quantifiable preferences for each possible component outcome. These findings were incorporated into a novel composite endpoint weighting technique.

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