Risk factors for medication-overuse headache: An 11-year follow-up study. The Nord-Trøndelag Health Studies

Pain ◽  
2012 ◽  
Vol 153 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Knut Hagen ◽  
Mattias Linde ◽  
Timothy J. Steiner ◽  
Lars Jacob Stovner ◽  
John-Anker Zwart
Keyword(s):  
Risk Factors ◽  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Follow Up Study ◽  
Health Studies

Risk factors in medication overuse headache: A one-year follow-up study

2010 ◽  
pp. 68-72 ◽  
Author(s):  
Natascia Ghiotto ◽  
Grazia Sances ◽  
Federica Galli ◽  
Cristina Tassorelli ◽  
Elena Guaschino ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Follow Up Study ◽  
One Year

Risk factors in medication-overuse headache: A 1-year follow-up study (care II protocol)

Cephalalgia ◽  
2009 ◽  
Vol 30 (3) ◽  
pp. 329-336 ◽  
Author(s):  
G Sances ◽  
N Ghiotto ◽  
F Galli ◽  
E Guaschino ◽  
C Rezzani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Treatment Strategies ◽  
Primary Headache ◽  
Headache Centre ◽  
Chi Squared ◽  
One Year ◽  
Predictor Factors

To investigate factors influencing prognosis in medication-overuse headache (MOH), we conducted a 12-month follow-up of patients with probable MOH. We recruited 215 patients consecutively admitted to our headache centre for an inpatient detoxification treatment. We analysed likely predictor factors for headache resolution (sex, age, primary headache, psychiatric comorbidity, type and timing of overuse). Mann–Whitney U-test and chi-squared test were used. One year after withdrawal, we had complete data on 172 patients (80%): 38 of these patients (22%) had relapsed into overuse and 134 (78%) had not. The negative prognostic factors for relapse were: intake of more than 30 doses/month ( P = 0.004), smoking ( P = 0.012), alcohol consumption ( P = 0.037), non-confirmation of MOH diagnosis 2 months after detoxification ( P = 0.000), and return to overused drug(s) ( P = 0.000). The 1-year relapse rate was 22%. The existence of sub-groups of MOH patients with such risk factors could influence treatment strategies.

scholarly journals The “care” protocol: outcome of medication overuse headache in a three year follow-up study

2013 ◽  
Vol 14 (S1) ◽  
Author(s):  
G Sances ◽  
N Ghiotto ◽  
F Galli ◽  
M Allena ◽  
A Frustaci ◽  
...  
Keyword(s):  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Follow Up Study ◽  
Care Protocol

Detoxification in medication-overuse headache, a retrospective controlled follow-up study: Does care by a headache nurse lead to cure?

Cephalalgia ◽  
2015 ◽  
Vol 36 (2) ◽  
pp. 122-130 ◽  
Author(s):  
JA Pijpers ◽  
MA Louter ◽  
ME de Bruin ◽  
EW van Zwet ◽  
FG Zitman ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Outcome Measures ◽  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Primary Headache ◽  
Relative Reduction ◽  
Follow Up Study ◽  
Headache Diagnosis ◽  
Withdrawal Therapy

Aim J.A.P. and M.A.L. contributed equally to this manuscript. The aim of this article is to determine whether support by a headache nurse in the treatment of medication-overuse headache (MOH) increases successful withdrawal, and to study determinants of response to withdrawal therapy. Methods A retrospective, controlled follow-up study was performed with 416 MOH patients. All patients were treated with outpatient withdrawal therapy, with two treatment arms: with or without the support of a specialised headache nurse. The outcome measures were: i) successful withdrawal, defined as discontinuation of all headache medication according to the study protocol; and ii) the responder rate, defined as the percentage of patients with ≥50% reduction in headache days after successful withdrawal and iii) relative reduction in headache days after successful withdrawal. Results Successful withdrawal percentages were significantly higher in the group supported by the headache nurse than in the group without support (73.1% vs. 60.7%; p = 0.008), which was confirmed in multivariate analysis (OR 1.73, 95% CI 1.11–2.71, p = 0.016). Support by a headache nurse was not associated with response. The underlying primary headache diagnosis, determined after withdrawal, was significantly correlated with response. Conclusion The support by a headache nurse results in an increased adherence to detoxification.

scholarly journals The “care” protocol: the role of personality in a three-year follow-up study of medication overuse headache

2013 ◽  
Vol 1 (Suppl 1) ◽  
pp. P174
Author(s):  
F Galli ◽  
G Sances ◽  
N Ghiotto ◽  
A Frustaci ◽  
E Guaschino ◽  
...  
Keyword(s):  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Follow Up Study ◽  
Care Protocol

Medication Overuse Headache: Rates and Predictors for Relapse in a 4-year Prospective Study

Cephalalgia ◽  
2005 ◽  
Vol 25 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Z Katsarava ◽  
M Muessig ◽  
A Dzagnidze ◽  
G Fritsche ◽  
HC Diener ◽  
...  
Keyword(s):  
Prospective Study ◽  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Primary Headache ◽  
Tension Type Headache ◽  
First Year ◽  
Follow Up Study ◽  
Type Headache

We present a prospective 4-year follow-up study of 96 patients with medication overuse headache following withdrawal. Complete datasets were available from 85 patients (89%) 6 months, from 79 patients (82%) 1 year and from 75 patients (78%) 4 years after withdrawal. Twenty-six patients (31%) relapsed within the first 6 months after withdrawal. The number of relapses increased to 32 (41%) 1 year and to 34 (45%) 4 years after withdrawal. The 4-year relapse rate was lower in migraine than in tension-type headache (32% vs. 91%, P ≤ 0.001) and combination of migraine and tension-type headache (32% vs. 70%, P ≤ 0.027) and also lower in patients overusing triptans than analgesics (21% vs. 71%, P ≤ 0.001). The study suggests that the majority of relapses occur within the first year after withdrawal and that the long-term success of withdrawal depends on the type of primary headache and the type of overused medication.

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