BDNF Val66Met polymorphism is associated with verbal memory dysfunction in Parkinson’s disease

2018 ◽  
Vol 46 ◽  
pp. e78-e79
Author(s):  
J.H. Hong ◽  
Y.J. Kim ◽  
J.S. Park ◽  
Y.E. Kim ◽  
B.S. Ye ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Verbal Memory ◽  
Memory Dysfunction ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism

Pattern of cortical thinning associated with the BDNF Val66Met polymorphism in Parkinson’s disease

2019 ◽  
Vol 372 ◽  
pp. 112039 ◽  
Author(s):  
Frederic Sampedro ◽  
Juan Marín-Lahoz ◽  
Saul Martínez-Horta ◽  
Javier Pagonabarraga ◽  
Jaime Kulisevsky
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Val66met Polymorphism ◽  
Cortical Thinning ◽  
Bdnf Val66met Polymorphism

The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson’s disease

2005 ◽  
Vol 252 (7) ◽  
pp. 833-838 ◽  
Author(s):  
Th. Foltynie ◽  
S. G. J. Lewis ◽  
T. E. Goldberg ◽  
A. D. Blackwell ◽  
B. S. Kolachana ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Val66met Polymorphism ◽  
Planning Ability ◽  
Bdnf Val66met Polymorphism ◽  
Gender Specific ◽  
Specific Influence

scholarly journals Association of BDNF Val66MET Polymorphism With Parkinson’s Disease and Depression and Anxiety Symptoms

2017 ◽  
Vol 29 (2) ◽  
pp. 142-147 ◽  
Author(s):  
Fernanda Carvalho Cagni ◽  
Clarissa Loureiro das Chagas Campêlo ◽  
Daniel Gomes Coimbra ◽  
Mayara Rodrigues Barbosa ◽  
Luiz Gonzaga Oliveira Júnior ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Anxiety Symptoms ◽  
Depression And Anxiety ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism

BDNF Val66Met polymorphism is associated with cognitive impairment in Italian patients with Parkinson’s disease

2009 ◽  
Vol 16 (11) ◽  
pp. 1240-1245 ◽  
Author(s):  
F. R. Guerini ◽  
E. Beghi ◽  
G. Riboldazzi ◽  
R. Zangaglia ◽  
C. Pianezzola ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism

Lack of association between the BDNF Val66Met polymorphism and Parkinson's disease in a Swedish population

2003 ◽  
Vol 53 (6) ◽  
pp. 823-823 ◽  
Author(s):  
Anna Håkansson ◽  
Jonas Melke ◽  
Lars Westberg ◽  
Haydeh Niazi Shahabi ◽  
Silva Buervenich ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Swedish Population ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism

scholarly journals Non-Motor Symptoms after One Week of High Cadence Cycling in Parkinson’s Disease

2019 ◽  
Vol 16 (12) ◽  
pp. 2104 ◽  
Author(s):  
Sara A. Harper ◽  
Bryan T. Dowdell ◽  
Jin Hyun Kim ◽  
Brandon S. Pollock ◽  
Angela L. Ridgel
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Depression Symptoms ◽  
Motor Cognition ◽  
Val66met Polymorphism ◽  
Main Effect ◽  
Bdnf Val66met Polymorphism ◽  
Global Cognition ◽  
Non Motor Symptoms ◽  
High Cadence

The objective was to investigate if high cadence cycling altered non-motor cognition and depression symptoms in individuals with Parkinson’s disease (PD) and whether exercise responses were influenced by brain-derived neurotrophic factor (BDNF) Val66Met polymorphism. Individuals with idiopathic PD who were ≥50 years old and free of surgical procedures for PD were recruited. Participants were assigned to either a cycling (n = 20) or control (n = 15) group. The cycling group completed three sessions of high cadence cycling on a custom motorized stationary ergometer. The primary outcome was cognition (attention, executive function, and emotion recognition were assessed via WebNeuro® and global cognition via Montreal Cognitive Assessment). Depression symptoms were assessed via Beck Depression Inventory-II. There was a main effect of time for emotional recognition (p = 0.048), but there were no other changes in cognition or depression symptoms. Regardless of intervention or Val66Met polymorphism, high cadence cycling does not alter cognition or depression symptoms after three sessions in one week.

scholarly journals Cognitive training interventions for dementia and mild cognitive impairment in Parkinson’s disease - A cochrane review summary with commentary

2021 ◽  
pp. 1-3
Author(s):  
Tobias Loetscher
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Training ◽  
Verbal Memory ◽  
Cognitive Impairments ◽  
Cochrane Review ◽  
Cognitive Domains ◽  
Training Interventions

BACKGROUND: The majority of people living with Parkinson’s disease will develop impairments in cognition. These impairments are associated with a reduced quality of life. OBJECTIVE: The Cochrane Review aimed to investigate whether cognitive training improves cognition in people with Parkinson’s disease and mild cognitive impairments or dementia. METHODS: A Cochrane Review by Orgeta et al. was summarized with comments. RESULTS: The review included seven studies with a total of 225 participants. There was no evidence for improvements in global cognition when cognitive training was compared to control conditions. Observed improvements in attention and verbal memory measures after cognitive training could not be confirmed in a subsequent sensitivity analysis. There was no evidence for benefits in other cognitive domains or quality of life measures. The certainty of the evidence was low for all comparisons. CONCLUSIONS: The effectiveness of cognitive training for people with Parkinson’s disease and cognitive impairments remains inconclusive. There is a pressing need for adequately powered trials with higher methodological quality.

scholarly journals Verbal memory is associated with structural hippocampal changes in newly diagnosed Parkinson's disease

2012 ◽  
Vol 84 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Mona K Beyer ◽  
Kolbjorn S Bronnick ◽  
Kristy S Hwang ◽  
Niels Bergsland ◽  
Ole Bjorn Tysnes ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Verbal Memory ◽  
Newly Diagnosed
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