Toll-like receptor 4 deficiency facilitates α-synuclein propagation and neurodegeneration in a mouse model of prodromal Parkinson's disease

Parkinsonism & Related Disorders ◽

10.1016/j.parkreldis.2021.09.007 ◽

2021 ◽

Vol 91 ◽

pp. 59-65

Author(s):

Serena Venezia ◽

Walter A. Kaufmann ◽

Gregor K. Wenning ◽

Nadia Stefanova

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Mouse Model ◽

Toll Like Receptor ◽

Toll Like Receptor 4

Download Full-text

The Potential Role of Toll-Like Receptor 4 in Mediating Dopaminergic Cell Loss and Alpha-Synuclein Expression in the Acute MPTP Mouse Model of Parkinson’s Disease

Journal of Molecular Neuroscience ◽

10.1007/s12031-018-1057-7 ◽

2018 ◽

Vol 64 (4) ◽

pp. 611-618 ◽

Cited By ~ 9

Author(s):

Giuseppina Mariucci ◽

Rita Pagiotti ◽

Francesco Galli ◽

Luigina Romani ◽

Carmela Conte

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Mouse Model ◽

Potential Role ◽

Cell Loss ◽

Alpha Synuclein ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Dopaminergic Cell

Download Full-text

The lack of toll-like receptor 4 promotes up-regulation and delocalization of neutral sphingomyelinase in the MPTP mouse model of Parkinson's disease

Journal of Biotechnology ◽

10.1016/j.jbiotec.2019.05.102 ◽

2019 ◽

Vol 305 ◽

pp. S27

Author(s):

M. Codini ◽

S. Cataldi ◽

I. Ferri ◽

M. Laurenti ◽

M. Ceccarini ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Mouse Model ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Neutral Sphingomyelinase

Download Full-text

Interaction between toll-like receptor 4 (TLR4) gene and alcohol drinking on Parkinson’s disease risk in Chinese Han population

Journal of Clinical Neuroscience ◽

10.1016/j.jocn.2018.12.002 ◽

2019 ◽

Vol 62 ◽

pp. 128-132

Author(s):

Zhenyan Li ◽

Aijun Song ◽

Haining Yu

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Alcohol Drinking ◽

Disease Risk ◽

Chinese Han Population ◽

Toll Like Receptor ◽

Chinese Han ◽

Toll Like Receptor 4 ◽

Han Population ◽

Tlr4 Gene

Download Full-text

Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson’s disease

Scientific Reports ◽

10.1038/srep14764 ◽

2015 ◽

Vol 5 (1) ◽

Cited By ~ 29

Author(s):

Won-Ho Shin ◽

Min-Tae Jeon ◽

Eunju Leem ◽

So-Yoon Won ◽

Kyoung Hoon Jeong ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Pathogenic Mechanism ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Kringle 2

Download Full-text

247 The Role of Toll-Like Receptor-4 in Gut-Brain Cross Talk in a Murine Model of Parkinson's Disease

Gastroenterology ◽

10.1016/s0016-5085(14)60206-7 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-59

Author(s):

Paula Perez-Pardo ◽

Hidde Douna ◽

Tom Wijnands ◽

Sofia Lopes da Silva ◽

Christopher B. Forsyth ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cross Talk ◽

Murine Model ◽

Toll Like Receptor ◽

Toll Like Receptor 4

Download Full-text

The role of Toll-like receptor-4 (TLR4) in gut-brain cross talk in a murine model for Parkinson’s disease

European Neuropsychopharmacology ◽

10.1016/s0924-977x(16)31753-9 ◽

2016 ◽

Vol 26 ◽

pp. S650

Author(s):

P. Perez-Pardo ◽

H.B. Dodiya ◽

J. Garssen ◽

A. Keshavarzian ◽

A. Kraneveld

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cross Talk ◽

Murine Model ◽

Toll Like Receptor ◽

Toll Like Receptor 4

Download Full-text

Toll-Like Receptor Expression in the Blood and Brain of Patients and a Mouse Model of Parkinson's Disease

The International Journal of Neuropsychopharmacology ◽

10.1093/ijnp/pyu103 ◽

2014 ◽

Vol 18 (6) ◽

pp. pyu103-pyu103 ◽

Cited By ~ 43

Author(s):

J. Drouin-Ouellet ◽

I. St-Amour ◽

M. Saint-Pierre ◽

J. Lamontagne-Proulx ◽

J. Kriz ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Mouse Model ◽

Receptor Expression ◽

Toll Like Receptor

Download Full-text

Diffusion kurtosis imaging detects a very early α-synuclein accumulation induced changes in transgenic mouse model of parkinson’s disease overexpressing α-synuclein

10.26226/morressier.5785edc7d462b80296c994db ◽

2016 ◽

Author(s):

Anas Arab

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Diffusion Kurtosis Imaging ◽

Induced Changes ◽

Diffusion Kurtosis

Download Full-text

Faculty Opinions recommendation of Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733700001.793551488 ◽

2018 ◽

Author(s):

Vladimir Uversky

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Mouse Model ◽

Cell Loss ◽

Synapsin Iii

Download Full-text

ERK/MAP Kinase Activation is Evident in Activated Microglia of the Striatum and Substantia Nigra in an Acute and Chronically-Induced Mouse Model of Parkinson’s Disease

Current Neurovascular Research ◽

10.2174/1567202616666181123152601 ◽

2019 ◽

Vol 15 (4) ◽

pp. 336-344 ◽

Cited By ~ 5

Author(s):

Sumit Sarkar ◽

Edward Lu ◽

James Raymick ◽

Joseph Hanig ◽

Qiang Gu

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Substantia Nigra ◽

Mouse Model ◽

Map Kinase ◽

Kinase Activation ◽

Activated Microglia

Download Full-text