Inefficient reserves in fault block belongs to low permeability thin interbed, thus water flooding development process has exposed many contradictions which are serious heterogeneity, large difference of suction of interlayer. Entering the water injection development, the injected water which rapidly advance along the high permeability channel causes water channeling and water flooding, which intenses development contradictions between layers. The reservoir numerical simulation technology on computer can reappear the movement of water and gas in the underground reservoir development process and describes the underground remaining oil distribution of inefficient reserves in complex fault block, which summarizes the remaining oil distribution rule of the water flooding development for complex fault block of inefficient reserves and provides basis for the establishment of oil field development adjustment scheme.